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Stable Isotopes Product Detail
Home Stable Isotopes CS-T-98769

b-Nicotinamide-d4 Mononucleotide (d4-major)

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Product Code: CS-T-98769 Stable Isotopes Research Use Only
b-Nicotinamide-d4 Mononucleotide (d4-major)
Category
Stable Isotopes
API Family
-
Product Code
CS-T-98769
Research Status
For Laboratory Use

b-Nicotinamide-d4 Mononucleotide (d4-major)

0 Stable Isotopes
Stock Status: : Enquire Live

CAT No.
CS-T-98769
CAS No.
-
Molecular Formula
C11H11D4N2O8P
Molecular Weight
338.24
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal or Veterinary use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
-
Product Code
CS-T-98769
M.F.
C11H11D4N2O8P
M.W.
338.24
Category
Stable Isotopes
Storage Condition
Refer MSDS for complete information.
IUPAC Name
b-Nicotinamide-d4 Mononucleotide (d4-major)
References
"Yoshino, J. et al.: Cell Metab., 14, 528 (2011); Caton, P.W. et al.: Diabetologia, 54, 3083 (2011); Formentini, L. et al.: BIochem. Pharmacol., 77, 1612 (2009);"
Synonyms
3-(Aminocarbonyl)-1-(5-O-phosphono-ß-D-ribofuranosyl)pyridinium-d4 Inner Salt;
Application Notes
"b-Nicotinamide-d4 Mononucleotide is the labelled analogue of a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation."
Hazard Compound
Refer MSDS for complete information.
Overview
"b-Nicotinamide-d4 Mononucleotide is the labelled analogue of a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation."

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