Stable Isotopes Product Detail

BMS 181174-d4

Name: BMS 181174-d4
Brand: Clearsynth
SKU: CS-T-97748
Availability: LimitedAvailability

Chemical Properties and Information

Product Code: CS-T-97748 Stable Isotopes

API Family

Product Code

CS-T-97748

BMS 181174-d4

Stable Isotopes

Stock Status: : Enquire Live

CAT No.

CS-T-97748

CAS No.

Molecular Formula

C₂₃H₂₁D₄N₅O₇S₂

Molecular Weight

551.63

There is no hazardous surcharge associated with this product.

There is no packaging charge associated with this product.

For Research Purposes only. Not for Personal use.

All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.

CAS No.

Product Code

CS-T-97748

M.F.

C₂₃H₂₁D₄N₅O₇S₂

M.W.

551.63

Category

Stable Isotopes

Storage Condition

Refer MSDS for complete information.

IUPAC Name

BMS 181174-d4

References

"Macaulay, V., et al.: Br. J. Cancer, 77, 2020 (1998); Xu, B., et al.: Cancer Res., 52, 6666 (1992); Kinoshita, S., et al.: J. Med. Chem., 14, 13 (1971), Beijnen, J.H., et al.: Anal. Profiles Drug Subs., 16, 361 (1986)"

Synonyms

"(1aS,8R,8aR,8bS)-8-[[(Aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-6-[[2-[(4-nitrophenyl)dithio]ethyl]amino]-azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione-d4; [1aS-(1aa,8ß,8aa,8ba)]-8-[[(Aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8"

Application Notes

"BMS 181174-d4 is labelled BMS 181174 (B595910), an analog of Mitomycin C (M371900) with activity against a range of tumour cell lines and xenografts, including MMC-resistant tumours. However, phase I clinical trials from Bristol-Myers Squibb demonstrated that the toxicity profile of BMS 181174 was no more favourable than that of mitomycin."

Hazard Compound

Refer MSDS for complete information.

Overview