Impurity Product Detail

Carfilzomib (2S,4R)-Diol

Name: Carfilzomib (2S,4R)-Diol
Brand: Clearsynth
SKU: CS-T-93647
Availability: LimitedAvailability

Chemical Properties and Information

Product Code: CS-T-93647 Impurity

API Family

Carfilzomib

Product Code

CS-T-93647

Carfilzomib (2S,4R)-Diol

Carfilzomib Impurity

Stock Status: : Enquire Live

CAT No.

CS-T-93647

CAS No.

Molecular Formula

C₄₀H₅₉N₅O₈

Molecular Weight

737.9

There is no hazardous surcharge associated with this product.

There is no packaging charge associated with this product.

For Research Purposes only. Not for Personal use.

All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.

CAS No.

Product Code

CS-T-93647

M.F.

C₄₀H₅₉N₅O₈

M.W.

737.9

Smiles

CC(C)C[C@H](NC([C@@H](NC(CN1CCOCC1)=O)CCC2=CC=CC=C2)=O)C(N[C@@H](CC3=CC=CC=C3)C(N[C@H](CC(C)C)C([C@@](C)(O)CO)=O)=O)=O

Category

Impurity

API Family

Carfilzomib

Storage Condition

Refer MSDS for complete information.

IUPAC Name

"(S)-N-((S)-1-(((2S,4R)-1,2-Dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide"

References

Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);

Synonyms

(S)-N-((S)-1-(((2S,4R)-1,2-dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

Application Notes

Carfilzomib (2S,4R)-Diol is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.

Hazard Compound

Refer MSDS for complete information.

Overview

Carfilzomib (2S,4R)-Diol is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.