Smiles
O=C([C@H](C)[C@@H](O[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)[C@H](C)[C@@H](O[C@H]2[C@H](O)[C@@H](N(C)C)C[C@@H](C)O2)[C@](C)(OC)C[C@H]3C)O[C@H](CC)[C@@](C)(OC)[C@H](O)[C@@H](C)C3=O
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-
methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12-hydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-
methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7,13-dimethoxy-3,5,7,9,11,13-
hexamethyloxacyclotetradecane-2,10-dione
Synonyms
6,12-Di-O-methylerythromycin A; Clarithromycin Impurity F; 12-O-Methyl Clarithromycin
Application Notes
12-O-Methyl Clarithromycin is a methylated impurity of the semi-synthetic macrolide antibiotic Clarithromycin (C559750). 12-O-Methyl Clarithromycin was shown to inhibit uptake of Clarithromycin into the lung cells.
Chen, X, et al,: Zhong, Yao,, 17, 32 (2008); Yoshida, H, et al,: Jap, J, Antibiot,, 53, 615 (2000); Omura, S, et al,: Yakug, Zas,, 112, 593 (1992); "
Purity by HPLC
Not less than 90%
Hazard Compound
Refer MSDS for accurate information.
Overview
12-O-Methyl Clarithromycin is a methylated impurity of the semi-synthetic macrolide antibiotic Clarithromycin (C559750). 12-O-Methyl Clarithromycin was shown to inhibit uptake of Clarithromycin into the lung cells.
Chen, X, et al,: Zhong, Yao,, 17, 32 (2008); Yoshida, H, et al,: Jap, J, Antibiot,, 53, 615 (2000); Omura, S, et al,: Yakug, Zas,, 112, 593 (1992); "
