Therapeutic Uses
Anti-Parkinsons
Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
Synonyms
Clonidine EP Impurity B
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Clonidine impurity B is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Clonidine impurity B usage and description
Clonidine impurity B is a chemical compound that is used in the pharmaceutical industry as a reference standard for analytical purposes. It is an impurity that is often present in Clonidine Hydrochloride, a drug used to treat high blood pressure, attention deficit hyperactivity disorder (ADHD), and anxiety disorders. Clonidine impurity B is also known as 2,6-Dichlorobenzamide, and it has a molecular weight of 192.99 g/mol.
The chemical formula for Clonidine impurity B is C7H5Cl2NO, and it has a melting point of 119-121ยฐC. It is a white crystalline solid that is soluble in organic solvents like methanol, ethanol, and dichloromethane. Clonidine impurity B is classified as a chlorobenzamide derivative, and it is a potential genotoxic impurity that can cause DNA damage.
The presence of Clonidine impurity B in Clonidine Hydrochloride can affect the quality, safety, and efficacy of the drug. Therefore, it is important to monitor and control the levels of this impurity in pharmaceutical products. Analytical methods like high-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS) are used to detect and quantify Clonidine impurity B in pharmaceutical samples.
In conclusion, Clonidine impurity B is an important reference standard in the pharmaceutical industry, and its chemical information is crucial for quality control purposes.