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Stable Isotopes Product Detail
Home Stable Isotopes CS-T-96984

Darinaparsin-d5

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Product Code: CS-T-96984 Stable Isotopes Research Use Only
Darinaparsin-d5
Category
Stable Isotopes
API Family
-
Product Code
CS-T-96984
Research Status
For Laboratory Use

Darinaparsin-d5

0 Stable Isotopes
Stock Status: : Enquire Live

CAT No.
CS-T-96984
CAS No.
-
Molecular Formula
C12H17D5AsN3O6S
Molecular Weight
416.34
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal or Veterinary use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
-
Product Code
CS-T-96984
M.F.
C12H17D5AsN3O6S
M.W.
416.34
Category
Stable Isotopes
Storage Condition
Refer MSDS for complete information.
IUPAC Name
Darinaparsin-d5
References
"Tian, J., et al.: Clin. Cancer Res., 18, 3366 (2012); Ning, S., et al.: Int. J. Radiat. Oncol. Biol. Phys., 65, 493 (2006);"
Synonyms
N-[S-(Dimethylarsino)-N-L-?-glutamyl-L-cysteinyl]-glycine-d5; Dimethylarsinic Glutathione-d5; ZIO 101-d5; Zinapar-d5; L-?-Glutamyl-S-(dimethylarsino)-L-cysteinyl-glycine-d5
Application Notes
Darinaparsin-d5 is the isotope labelled analog of Darinaparsin. Darinaparsin is an arsenic cytotoxin that has been used in pharmacological activities to evaluate the effect on survival an radiosensitivity of tumor cells in vitro under normoxia and hypoxia and in vivo using xenograft models. Darinaparsin has significant and preferential cytotoxic and radiosensitizing effects on solid tumors as compared with normal cells.  Darinaparsin may therefore increase the therapeutic index of radiation therapy and has near term translational potential.
Hazard Compound
Refer MSDS for complete information.
Overview
Darinaparsin-d5 is the isotope labelled analog of Darinaparsin. Darinaparsin is an arsenic cytotoxin that has been used in pharmacological activities to evaluate the effect on survival an radiosensitivity of tumor cells in vitro under normoxia and hypoxia and in vivo using xenograft models. Darinaparsin has significant and preferential cytotoxic and radiosensitizing effects on solid tumors as compared with normal cells.  Darinaparsin may therefore increase the therapeutic index of radiation therapy and has near term translational potential.

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