Product Detail
Dasatinib N-oxide
Dasatinib Metabolite
Stock Status: In Stock
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For Research & Analytical Purposes. Not for Personal use.
Category
Metabolite
API Family
Dasatinib
Storage
Store at refrigerator (2-8°C) for long term storage
Hazard Information
Refer MSDS for accurate information.
Dasatinib N-oxide Product Information
Dasatinib N-oxide is listed under Metabolite. It is associated with Dasatinib and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-O-06099.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.
Technical Data
Product Name
Dasatinib N-oxide
CAS No.
910297-52-8
CAT No.
CS-O-06099
Molecular Formula
C₂₂H₂₆ClN₇O₃S
Molecular Weight
504.00
Category
API Family
Storage Condition
Store at refrigerator (2-8°C) for long term storage
SMILES
O=C(C1=CN=C(NC2=NC(C)=NC(N3CC[N+]([O-])(CCO)CC3)=C2)S1)NC4=C(C)C=CC=C4Cl
IUPAC Name
4-(6-((5-((2-chloro-6-methylphenyl)carbamoyl)thiazol-2-yl)amino)-2-methylpyrimidin-4-yl)-1-(2-hydroxyethyl)piperazine 1-oxide
Purity by HPLC
>98%
Hazard Compound
Refer MSDS for accurate information.
Description
Overview
An oxidative metabolite of Dasatinib (M5 metabolite).
Synonyms
4-(6-((5-((2-chloro-6-methylphenyl)carbamoyl)thiazol-2-yl)amino)-2-methylpyrimidin-4-yl)-1-(2-hydroxyethyl)piperazine 1-oxide
Application Notes
An oxidative metabolite of Dasatinib (M5 metabolite).
References
"Cashman; J,R,; et al,: Chem, Res, Toxicol,; 8; 165 (1995); Aasmoe; L,; et al,: Toxicol, Appl, Pharmacol,; 150; 86 (1998); Galetin; A,; et al,: J, Pharmacol, Exp, Ther,; 314; 180 (2005); Christopher; L,J,; et al,: Drug Metab, Dispos,; 36; 1357 (2008);"
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