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Deoxynivalenol

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Product Code: CS-T-52001 API Research Use Only
Deoxynivalenol
Category
API
API Family
Deoxynivalenol
Product Code
CS-T-52001
Research Status
For Laboratory Use

Deoxynivalenol

Deoxynivalenol API
Stock Status: In Stock
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CAT No.
CS-T-52001
CAS No.
51481-10-8
Molecular Formula
C15H20O6
Molecular Weight
296.32
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal or Veterinary use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
51481-10-8
Product Code
CS-T-52001
M.F.
C15H20O6
M.W.
296.32
Smiles
C[C@]1(C[C@H]2O)[C@]3(CO3)[C@]2([H])O[C@@](C=C4C)([H])[C@@]1([C@@H](C4=O)O)CO
Category
API
API Family
Deoxynivalenol
Storage Condition
Store at freezer (-20°C) for long term storage
IUPAC Name
"(2S,2'R,3'R,5'R,5a'R,6'S,9a'R)-3',6'-Dihydroxy-5a'-(hydroxymethyl)-5',8'-dimethyl-2',3',4',5',5a',9a'-hexahydrospiro[oxirane-2,10'-[2,5]methanobenzo[b]oxepin]-7'(6'H)-one"
References
Bae, et al.: Toxicol. Sci., 105, 59 (2008), Shi, et al.: Toxicol. Sci., 109, 247 (2009), Krishnaswamy, et al.: Free Radic. Biol. Med., 49 50 (2010),
Synonyms
Spiro[2,5-methano-1-benzoxepin-10,2′-oxirane], trichothec-9-en-8-one deriv. (ZCI)
Application Notes
Deoxynivalenol is a tricothecene mycotoxin and potent protein synthesis inhibitor. Deoxynivalenol exhibits cytotoxic activity in vivo via the ribotoxic stress response. Deoxynivalenol induces p38-mediated gene expression and apoptosis in leukocytes; activity results in systemic expression of interleukin-6 (IL-6) and other proinflammatory cytokines. Also induces migration of NF-B into the nucleus.
Purity by HPLC
Not less than 90%
Hazard Compound
Refer MSDS for accurate information.
Overview
Deoxynivalenol is a tricothecene mycotoxin and potent protein synthesis inhibitor. Deoxynivalenol exhibits cytotoxic activity in vivo via the ribotoxic stress response. Deoxynivalenol induces p38-mediated gene expression and apoptosis in leukocytes; activity results in systemic expression of interleukin-6 (IL-6) and other proinflammatory cytokines. Also induces migration of NF-B into the nucleus.

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