Product Detail
Desdifluoro Dolutegravir-d7
Stable Isotopes
Stock Status: Enquire
Live
For Research & Analytical Purposes. Not for Personal use.
Category
Stable Isotopes
API Family
--
Storage
Refer MSDS for complete information.
Hazard Information
Refer MSDS for complete information.
Desdifluoro Dolutegravir-d7 Product Information
Desdifluoro Dolutegravir-d7 is listed under Stable Isotopes. It is associated with and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-T-96369.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.
Technical Data
Product Name
Desdifluoro Dolutegravir-d7
CAS No.
-
CAT No.
CS-T-96369
Molecular Formula
C20H14D7N3O5
Molecular Weight
390.44
Category
Storage Condition
Refer MSDS for complete information.
IUPAC Name
Desdifluoro Dolutegravir-d7
Hazard Compound
Refer MSDS for complete information.
Description
Overview
"Desdifluoro Dolutegravir-d7 is impurity B of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector."
Synonyms
Desdifluoro Dolutegravir-d7
Application Notes
"Desdifluoro Dolutegravir-d7 is impurity B of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector."
References
"Kobayashi, M. et al. Antimicrob Agents Chemother., 55, 813 (2011); Garrido, C. et al.: Antiviral, Res., 90, 164 (2011); Lenz, J.C.C. et al.: Exp. Opin. Invest. Drugs, 20, 537 (2011);"
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