Therapeutic Uses
Anti-Diabetic
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
Pioglitazone Impurity B (E/Z Mixture)
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Yes -Refer MSDS for accurate information
Didehydro Pioglitazone is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
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Didehydro Pioglitazone usage and description
Didehydro Pioglitazone is a drug that is used to treat type 2 diabetes. It is a member of the thiazolidinedione class of drugs and works by increasing the body's sensitivity to insulin, which helps to lower blood sugar levels. It is a metabolite of pioglitazone, which is another drug used to treat diabetes.
Chemically, didehydro pioglitazone is a derivative of thiazolidinedione that contains a double bond in the 5,6 position of the thiazolidinedione ring. It is also known as 5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione. It has a molecular weight of 383.5 g/mol and a molecular formula of C22H22N2O3S.
The recommended dose of didehydro pioglitazone is 15-45 mg per day, taken orally. It is metabolized in the liver and excreted in the urine. It has a half-life of approximately 6-7 hours.
While didehydro pioglitazone is generally well-tolerated, it may cause some side effects, including weight gain, edema, headache, and upper respiratory tract infection. It may also increase the risk of bladder cancer, so it should not be used in patients with a history of bladder cancer or in those with uncontrolled heart failure. Patients with liver disease or a history of liver disease should also use caution when taking this medication.
