DM4-d6

796073-69-3(unlabelled)

CS-T-103304

C₃₈H₄₈D₆ClN₃O₁₀S

786.4

C[C@@H]1[C@@H]2C[C@](NC(O2)=O)(O)[C@H](OC)/C=C/C=C(C)/CC3=CC(N(C)C(C[C@H](OC([C@@H](N(C(CCC(C([2H])([2H])[2H])(S)C([2H])([2H])[2H])=O)C)C)=O)[C@@]4(C)[C@H]1O4)=O)=C(Cl)C(OC)=C3

Stable Isotopes

-

Refer MSDS for complete information.

N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)-maytansine-d6; Maytansinoid DM4-d6

Erickson, H., et. al.: Cancer Res., 66, 4426 (2006);Widdison, W., et al.: J. Med. Chem., 49, 4392 (2006)

N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)-maytansine-d6; Maytansinoid DM4-d6

DM4-d6 is an isotopically labelled analog of 2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)-maytansine (D198090), which is an intermediate used to prepare semisynthetic maytansine analogs which can be conjugated with antibodies for targeted treatment of cancer.

Refer MSDS for complete information.