API Product Detail

Dolutegravir

Name: Dolutegravir
Brand: Clearsynth
SKU: CS-O-00218
Availability: LimitedAvailability

Chemical Properties and Information

Product Code: CS-O-00218 API

API Family

Dolutegravir

Product Code

CS-O-00218

Dolutegravir

Dolutegravir API

Stock Status: In Stock
Live

CAT No.

CS-O-00218

CAS No.

1051375-16-6

Molecular Formula

C₂₀H₁₉F₂N₃O₅

Molecular Weight

419.38

There is no hazardous surcharge associated with this product.

There is no packaging charge associated with this product.

For Research Purposes only. Not for Personal use.

All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.

CAS No.

1051375-16-6

Product Code

CS-O-00218

M.F.

C₂₀H₁₉F₂N₃O₅

M.W.

419.38

Smiles

O=C1C=2N(C[C@]3(N1[C@H](C)CCO3)[H])C=C(C(NCC4=C(F)C=C(F)C=C4)=O)C(=O)C2O

Category

API

API Family

Dolutegravir

Storage Condition

Store at refrigerator (2-8°C) for long term storage

IUPAC Name

(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

References

"Kobayashi; M, et al, Antimcrob Agentschemother,; 55; 813 (2011); Garrido;c, et al,: Antiviral; Res,; 90; 164 (2011); Lenz; Jcc, et al,: Exp, Opin, Invest, Drugs; 20; 537 (2011);"

Synonyms

(4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

Application Notes

Dolutegravir is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peri

Purity by HPLC

Not less than 95%

Hazard Compound

Refer MSDS for accurate information.

Overview