Product Detail
Imatinib EP Impurity C
Imatinib Impurity
Stock Status: In Stock
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For Research & Analytical Purposes. Not for Personal use.
Category
Impurity
API Family
Imatinib
Storage
Store at refrigerator (2-8°C) for long term storage
Hazard Information
Refer MSDS for accurate information.
Imatinib EP Impurity C Product Information
Imatinib EP Impurity C is listed under Impurity. It is associated with Imatinib and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-O-05955.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.
Technical Data
Product Name
Imatinib EP Impurity C
CAS No.
404844-02-6
CAT No.
CS-O-05955
Molecular Formula
C28H29N7O
Molecular Weight
479.58
Category
API Family
Storage Condition
Store at refrigerator (2-8°C) for long term storage
SMILES
O=C(NC1=CC=C(C)C(NC2=NC=CC(C3=CC=CN=C3)=N2)=C1)C4=CC=C(CN5CCNCC5)C=C4
IUPAC Name
N-[4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)benzamide
Purity by HPLC
>98%
Hazard Compound
Refer MSDS for accurate information.
Description
Overview
"A metabolite of Gleevec, a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL)."
Synonyms
N-Desmethyl Imatinib Impurity
Application Notes
"A metabolite of Gleevec, a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL)."
References
"Schindler; T,; et al,: Science; 289; 1938 (2000); Drucker; B,J,; et al,: N, Engl, J, Med,; 344; 1031 (2001)"
