API Family
Isosorbide Mononitrate
Storage Condition
Store at freezer (-20°C) for long term storage
Synonyms
(3S,3aS,6R,6aR)-6-hydroxyhexahydrofuro[3,2-b]furan-3-yl nitrate
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90%
Hazard Compound
Yes -Refer MSDS for accurate information
Isosorbide-2-Mononitrate is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Isosorbide-2-Mononitrate usage and description
Isosorbide-2-mononitrate (ISMN) is a medication used in the treatment of angina pectoris, a condition characterized by chest pain caused by inadequate blood flow to the heart muscle. ISMN is a nitrate drug that works by relaxing the smooth muscles in the blood vessels, allowing for increased blood flow to the heart. This medication is typically taken orally in the form of tablets or capsules and is rapidly absorbed by the body.
ISMN is a derivative of isosorbide dinitrate and is metabolized in the liver to release nitric oxide, which causes dilation of the blood vessels. This dilation reduces the workload of the heart, which in turn reduces the frequency and severity of angina attacks. The medication has a half-life of approximately 5 hours, meaning that it is eliminated from the body relatively quickly.
In addition to its therapeutic effects, ISMN has some potential side effects. The most common side effect is headache, which occurs in up to 30% of patients. Other side effects include dizziness, nausea, and flushing. Rarely, ISMN can cause severe hypotension or methemoglobinemia, a condition where the blood is unable to carry oxygen effectively.
Overall, ISMN is an effective medication for the treatment of angina pectoris, and its benefits typically outweigh its potential side effects. However, as with any medication, it should be used under the guidance of a medical professional to ensure its safe and effective use.
