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CAS No.
-
Product Code
CS-T-99188
M.F.
C27H16D6BrNO4S
M.W.
542.47
Category
Stable Isotopes
Storage Condition
Refer MSDS for complete information.
IUPAC Name
L-798106-d6
References
"Kobayashi, K. et al.: Eur. J. Pharmacol., 660, 375 (2011); Su, X. et al.: Am. J. Physiol. Renal Physiol., 295, F984 (2008); Bassil, A.K. et al.: Br. J. Pharmacol. 154, 126 (2008); Jugus, M.J. et al.: Br. J. Pharmacol., 158, 372 (2009); Juteau, H. et al.:"
Synonyms
(2E)-N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide-d6; CM 9-d6; GW 671021-d6;
Application Notes
"Labelled analogue of L-798106, a potent and selective prostanoid receptor EP3-selective antagonists. L-798106 has been used in multiple studies to tease out EP3 agonist activity, both in vitro and in vivo. L-798106 successfully blocks the actions of sulprostone, an EP3-selective agonist. L-798106 was useful in showing that the vascular contraction effect of PGE2 is due to its prostanoid EP3 agonist activity."
Hazard Compound
Refer MSDS for complete information.
Overview
"Labelled analogue of L-798106, a potent and selective prostanoid receptor EP3-selective antagonists. L-798106 has been used in multiple studies to tease out EP3 agonist activity, both in vitro and in vivo. L-798106 successfully blocks the actions of sulprostone, an EP3-selective agonist. L-798106 was useful in showing that the vascular contraction effect of PGE2 is due to its prostanoid EP3 agonist activity."