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Ledipasvir D tartrate

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Product Code: CS-O-16784 Impurity Research Use Only
Ledipasvir D tartrate
Category
Impurity
API Family
Ledipasvir
Product Code
CS-O-16784
Research Status
For Laboratory Use

Ledipasvir D tartrate

Ledipasvir Impurity
Stock Status: In Stock
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CAT No.
CS-O-16784
CAS No.
1502654-87-6
Molecular Formula
C₅₃H₆₀F₂N₈O₁₂
Molecular Weight
1039.09
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal or Veterinary use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
1502654-87-6
Product Code
CS-O-16784
M.F.
C₅₃H₆₀F₂N₈O₁₂
M.W.
1039.09
Category
Impurity
API Family
Ledipasvir
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
"(2S,3S)-2,3-dihydroxybutanedioic acid;methyl N-[(2S)-1-[(6S)-6-[5-[9,9-difluoro-7-[2-[(1S,2S,4R)-3-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]-3-azabicyclo[2.2.1]heptan-2-yl]-3H-benzimidazol-5-yl]fluoren-2-yl]-1H-imidazol-2-yl]-5-azaspiro[2.4]heptan-5-yl]-3-methyl-1-oxobutan-2-yl]carbamate"
References
"Link JO, et al, Discovery of ledipasvir (GS-5885): a potent, once-daily oral NS5A inhibitor for the treatment of hepatitis C virus infection, J Med Chem, 2014 Mar 13;57(5):2033-46; Hernandez D, et al, Natural prevalence of NS5A polymorphisms in subjects infected with hepatitis C virus genotype 3 and their effects on the antiviral activity of NS5A inhibitors, J Clin Virol, 2013 May;57(1):13-8,"
Synonyms
NA
Application Notes
"Ledipasvir D-tartrate is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon."
Purity by HPLC
Not less than 95 %
Hazard Compound
Refer MSDS for accurate information.
Overview
"Ledipasvir D-tartrate is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon."

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