Therapeutic Uses
Anti-Migraines
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
N-Desmethyl Diltiazem-d4 Hydrochloride, 1217650-51-5
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Yes -Refer MSDS for accurate information
N-Desmethyl Diltiazem-d4 Hydrochloride is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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N-Desmethyl Diltiazem-d4 Hydrochloride usage and description
N-Desmethyl Diltiazem D4 hydrochloride, also known as Diltiazem N-oxide, is a chemical compound that belongs to the class of calcium channel blockers. It is a derivative of Diltiazem, a medication used for the treatment of hypertension and angina pectoris.
N-Desmethyl Diltiazem D4 hydrochloride is used as a reference standard in analytical and pharmacological studies. It is also used in the development and validation of analytical methods for the quantification of Diltiazem N-oxide in biological samples.
Chemically, N-Desmethyl Diltiazem D4 hydrochloride is a hydrophilic compound with a molecular weight of 378.91 g/mol and a molecular formula of C22H25N2O3Cl. It is a white to off-white powder that is soluble in water and methanol.
N-Desmethyl Diltiazem D4 hydrochloride is known to inhibit the influx of calcium ions into cardiac and smooth muscle cells, leading to relaxation of the muscles and dilation of blood vessels. It has been found to have a moderate affinity for L-type calcium channels, which are responsible for the entry of calcium ions into cells.
In conclusion, N-Desmethyl Diltiazem D4 hydrochloride is a useful reference standard in analytical and pharmacological studies. Its chemical properties and mechanism of action make it a valuable tool in the development and validation of analytical methods for the quantification of Diltiazem N-oxide in biological samples.
