Therapeutic Uses
Anti-Cancer / Oncology
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
2-[3,5-bis(trifluoromethyl)phenyl]-3,3,3-trideuterio-N-methyl-N-[4-(2-methylphenyl)-6-piperazin-1-ylpyridin-3-yl]-2-(trideuteriomethyl)propanamide
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
N-Desmethyl Netupitant-d6 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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N-Desmethyl Netupitant-d6 usage and description
N-desmethyl netupitant D6 is a chemical compound that is used in the pharmaceutical industry for its antiemetic properties. It is a deuterated version of N-desmethyl netupitant, which is a selective neurokinin-1 (NK1) receptor antagonist. This means that it blocks the action of the NK1 receptor, which is responsible for transmitting signals of nausea and vomiting in the brain.
N-desmethyl netupitant D6 is typically administered as a tablet or capsule and is used to prevent nausea and vomiting associated with chemotherapy, radiation therapy, and surgery. It is also used to treat postoperative nausea and vomiting in adults. The deuterium-labeled version of the compound is used in research studies to better understand its pharmacokinetics and metabolism.
Chemically, N-desmethyl netupitant D6 has a molecular formula of C26H17D6F5N3O3 and a molecular weight of 517.54 g/mol. It is a white to off-white powder that is sparingly soluble in water and slightly soluble in ethanol. The compound is stable under normal storage conditions and should be protected from light and moisture.
In summary, N-desmethyl netupitant D6 is a valuable antiemetic drug used to prevent nausea and vomiting in cancer patients and those undergoing surgery. Its selective action on the NK1 receptor makes it a highly effective treatment option, and its deuterium-labeled version is used in research studies to better understand its pharmacokinetics and metabolism.
