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- Synonyms:Ponatinib Active Metabolite
- Chemical Name:3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)phenyl]benzamide
- Country of Origin:India
- Application Notes:Ponatinib Active Metabolite AP24567(M42) is a research reagent applied in pharmaceuticals and cancer treatment. Ponatinib Active Metabolite AP24567(M42) is an analog of Ponatinib (P688250) which is a tyrosine kinase inhibitors (TKI) and used to treat chronic myeloid leukemia (CML) (1,2,3). Ponatinib (P688250) is also used in combination with other drugs, such as forskolin, to combat TKI resistance in patient with CML (3), targeted drug in small-cell lung cancer. Potent FAK inhibitor. FGFR/VEGFR/Bcr-Abl inhibitor It is a COVID19-related research product.
- Product Category:Ponatinib Metabolites
N-Desmethyl ponatinib is identified by CAS No. 943319-87-7 and is chemically known as Ponatinib Active Metabolite, IUPAC Name: 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)phenyl]benzamide.
N-Desmethyl ponatinib is provided with comprehensive characterization data in accordance with regulatory guidelines. It is suitable for use in analytical method development, method validation (AMV), Quality Control (QC) applications for Abbreviated New Drug Applications (ANDA) and commercial production of Ponatinib.
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The purchaser, user or importer of record is responsible for determining the accuracy of items at the time of ordering as it may change without notice as per current product specification.
This product is solely intended for research purposes and is not approved for human consumption.
