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CAS No.
-
Product Code
CS-T-99903
M.F.
C28H32D6N6O8
M.W.
592.67
Category
Stable Isotopes
Storage Condition
Refer MSDS for complete information.
IUPAC Name
Pemetrexed Tromethamine Amide-d6
References
"Vogelzang, N.J., et al.: J. Clin. Oncol., 21,2636 (2003); Paz-Ares, L., et al.: Lancet. Oncol., 13, 247 (2012)"
"Pemetrexed Tromethamine Amide-d6 is labelled Pemetrexed Tromethamine Amide (P219560) which is an impurity of Pemetrexed (P219550, Disodium Heptahydrate salt), an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Heptahydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes."
Hazard Compound
Refer MSDS for complete information.
Overview
"Pemetrexed Tromethamine Amide-d6 is labelled Pemetrexed Tromethamine Amide (P219560) which is an impurity of Pemetrexed (P219550, Disodium Heptahydrate salt), an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Heptahydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes."
![N-Boc-(1S)-3-[3-(3-(isopropyl-d6)-5-methyl-4H-1,2,4-triazol-4-yl)-exo-8-azabicyclo[3.2.1]oct-8-yl]-1-phenyl-1-propanamine](https://structures.clearsynth.com/CS-T-97746.png)
