There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
-
Product Code
CS-T-101015
M.F.
C21H14D4N4OS
M.W.
378.48
Category
Stable Isotopes
Storage Condition
Refer MSDS for complete information.
IUPAC Name
PF-3644022-d4
References
"Hegen, M., et al.: J. Immunol., 177, 1913 (2006); Anderson, D., et al.: J. Med. Chem., 50, 2647 (2007); Goldberg, D., et al.: Bioorg. Med. Chem. Lett., 18, 938 (2008); Burnette, B., et al.: Pharmacology, 84, 42 (2009); Mourey, et al.: J. Pharmacol. Exp. T"
"Labelled analogue of PF-3644022, a potent freely reversible ATP-competitive compound that inhibits MK2 activity (Ki = 3 nM) with good selectivity when profiled against 200 human kinases. PF-3644022 is a benzothiophene inhibitor of mitogen-activated protein kinase-activated protein kinase 2 inhibits tumor necrosis factor a production and has oral anti-inflammatory efficacy in acute and chronic models of inflammation."
Hazard Compound
Refer MSDS for complete information.
Overview
"Labelled analogue of PF-3644022, a potent freely reversible ATP-competitive compound that inhibits MK2 activity (Ki = 3 nM) with good selectivity when profiled against 200 human kinases. PF-3644022 is a benzothiophene inhibitor of mitogen-activated protein kinase-activated protein kinase 2 inhibits tumor necrosis factor a production and has oral anti-inflammatory efficacy in acute and chronic models of inflammation."
