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Stable Isotopes Product Detail
Home Stable Isotopes CS-T-96341

PSI-7977-13CD3

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Product Code: CS-T-96341 Stable Isotopes Research Use Only
PSI-7977-13CD3
Category
Stable Isotopes
API Family
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Product Code
CS-T-96341
Research Status
For Laboratory Use

PSI-7977-13CD3

Stable Isotopes
Stock Status: : Enquire Live

CAT No.
CS-T-96341
CAS No.
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Molecular Formula
C21¹³CH26D3FN3O9P
Molecular Weight
533.46
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal or Veterinary use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
NA
Product Code
CS-T-96341
M.F.
C21¹³CH26D3FN3O9P
M.W.
533.46
Category
Stable Isotopes
Storage Condition
Refer MSDS for complete information.
IUPAC Name
PSI-7977-13CD3
References
"Lam, A.M.,et al.: Antimicrob. Agents. Chemotherapy., 56, 3359 (2012); Lam, A.M., et al.: J. Virol., 85, 12334 (2011); Sofia, M.J., et al.: J. Medn. Chem., 53, 7202 (2010);"
Synonyms
"Isopropyl(2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl]methoxy-phenoxy-phosphoryl]amino]propanoate-13CD3; N-[[P(S),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-1-methylethyl Ester L-Alanine"
Application Notes
"PSI-7977-13CD3 is the isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-a-fluoro-ß-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase."
Hazard Compound
Refer MSDS for complete information.
Overview
"PSI-7977-13CD3 is the isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-a-fluoro-ß-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase."

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