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For Research Purposes only. Not for Personal use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
-
Product Code
CS-T-99105
M.F.
C28H25D3ClN3OS
M.W.
493.08
Category
Stable Isotopes
Storage Condition
Refer MSDS for complete information.
IUPAC Name
SAG-d3
References
"DeCamp, D., et al.: J. Biol. Chem., 275, 26322 (2000), Ahn, S., et al.: Nature, 437, 894 (2005), Huangfu, D., et al.: Development, 133, 3 (2006), Loulier, K., et al.: J. Neurochem., 98, 530 (2006),"
"SAG-d3 is the isotope labelled analog of SAG. SAG is a potent agonist of Hedgehog (Hh) signalling by activating the Smoothened (Smo) protein function. Studies identify novel properties of molecules displaying potential interest in the treatment of various cancers and brain diseases, and demonstrate that Smo is capable of signaling through G15."
Hazard Compound
Refer MSDS for complete information.
Overview
"SAG-d3 is the isotope labelled analog of SAG. SAG is a potent agonist of Hedgehog (Hh) signalling by activating the Smoothened (Smo) protein function. Studies identify novel properties of molecules displaying potential interest in the treatment of various cancers and brain diseases, and demonstrate that Smo is capable of signaling through G15."
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