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- Synonyms:Not available
- Chemical Name:propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-4-methyl-3-[[[(2S)-1-oxo-1-propan-2-yloxypropan-2-yl]amino]-phenoxyphosphoryl]oxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
- Country of Origin:India
- Application Notes:Sofosbuvir 3',5'-Bis-(S)-phosphate is an impurity of PSI-7977, a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-a-fluoro-ß-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
- Product Category:Sofosbuvir Impurities
Sofosbuvir 3’,5’-Bis-(S)-phosphate is identified by CAS No. 1337482-17-3 and is chemically known as Not available, IUPAC Name: propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-4-methyl-3-[[[(2S)-1-oxo-1-propan-2-yloxypropan-2-yl]amino]-phenoxyphosphoryl]oxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate.
Sofosbuvir 3’,5’-Bis-(S)-phosphate is provided with comprehensive characterization data in accordance with regulatory guidelines. It is suitable for use in analytical method development, method validation (AMV), Quality Control (QC) applications for Abbreviated New Drug Applications (ANDA) and commercial production of Sofosbuvir.
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The product information for any accuracy or completeness is as per the existing knowledge furnished during the creation of the webpage.
The purchaser, user or importer of record is responsible for determining the accuracy of items at the time of ordering as it may change without notice as per current product specification.
This product is solely intended for research purposes and is not approved for human consumption.
Sofosbuvir 3’,5’-Bis-(S)-phosphate
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