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For Research Purposes only. Not for Personal use.
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CAS No.
-
Product Code
CS-T-102052
M.F.
C38H34D4N4O6
M.W.
650.76
Category
Stable Isotopes
Storage Condition
Refer MSDS for complete information.
IUPAC Name
Tariquidar-d4
References
"Fox, E., et al.: Expert. Rev. Ainticancer. Ther., 7, 447 (2007); Hernandez, D., et al.: Biochem. Pharmacol., 85, 21 (2013); Bauer, F., et al.: Euro. J. Pharmacol., 696, 18 (2012);"
"Isotope Labelled analogue of Tariquidar (T007600), a p-glycoprotein drug efflux pump inhibitor. Tariquidar inhibits the ATPase activity of P-glycoprotein, suggesting that the modulating effect is derived from the inhibition of substrate binding, inhibition of ATP hydrolysis or both.Tariquidar can be considered an ideal agent for testing the role of P-glycoprotein inhibition in cancer"
Hazard Compound
Refer MSDS for complete information.
Overview
"Isotope Labelled analogue of Tariquidar (T007600), a p-glycoprotein drug efflux pump inhibitor. Tariquidar inhibits the ATPase activity of P-glycoprotein, suggesting that the modulating effect is derived from the inhibition of substrate binding, inhibition of ATP hydrolysis or both.Tariquidar can be considered an ideal agent for testing the role of P-glycoprotein inhibition in cancer"