1
- Synonyms:(1R,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enylmethanol dihydrochloride
- Chemical Name:[(1R,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol;hydrochloride
- Country of Origin:India
- Application Notes:trans-Abacavir Dihydrochloride is an impurity of Abacavir. Abacavir is a carbocyclic 2?-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
- Product Category:Abacavir Impurities
trans-Abacavir Dihydrochloride is identified by CAS No. 267668-71-3 and is chemically known as (1R,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enylmethanol dihydrochloride, IUPAC Name: [(1R,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol;hydrochloride.
trans-Abacavir Dihydrochloride is provided with comprehensive characterization data in accordance with regulatory guidelines. It is suitable for use in analytical method development, method validation (AMV), Quality Control (QC) applications for Abbreviated New Drug Applications (ANDA) and commercial production of Abacavir.
Page Keywords: Buy trans-Abacavir Dihydrochloride | Purchase trans-Abacavir Dihydrochloride | trans-Abacavir Dihydrochloride suppliers | trans-Abacavir Dihydrochloride manufacturers | trans-Abacavir Dihydrochloride price | trans-Abacavir Dihydrochloride Importer | trans-Abacavir Dihydrochloride Exporter
Disclaimer:
The product information for any accuracy or completeness is as per the existing knowledge furnished during the creation of the webpage.
The purchaser, user or importer of record is responsible for determining the accuracy of items at the time of ordering as it may change without notice as per current product specification.
This product is solely intended for research purposes and is not approved for human consumption.
