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Validamycin A

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Product Code: CS-CM-00183 API Research Use Only
Validamycin A
Category
API
API Family
Validamycin
Product Code
CS-CM-00183
Research Status
For Laboratory Use

Validamycin A

Validamycin API
Stock Status: In Stock
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CAT No.
CS-CM-00183
CAS No.
37248-47-8
Molecular Formula
C20H35NO13
Molecular Weight
497.49
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal or Veterinary use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
37248-47-8
Product Code
CS-CM-00183
M.F.
C20H35NO13
M.W.
497.49
Smiles
OC[C@@H](C[C@@H]([C@@H]([C@H]1O)O)N[C@H]2C=C([C@H]([C@@H]([C@H]2O)O)O)CO)[C@H]1O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO
Category
API
API Family
Validamycin
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
(2R,3R,4S,5S,6R)-2-[(1R,2R,3S,4S,6R)-2,3-dihydroxy-6-(hydroxymethyl)-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]cyclohexyl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
References
"Duncan J, Wardrop and Samanthi L, Waidyarachchi, ; Nat, Prod, Rep,; 2010; 27; 1431,"
Synonyms
(2R,3R,4S,5S,6R)-2-[(1R,2R,3S,4S,6R)-2,3-dihydroxy-6-(hydroxymethyl)-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]cyclohexyl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
Application Notes
"Validamycin A is the major analogue of a family of cyclitol disaccharides isolated from Streptomyces hygroscopicus var. limoneus by researchers at Takeda in 1970. Although commonly regarded as an aminoglycoside, validamycin shares little in common with conventional aminoglycosides such as streptomycin and gentamicin. Validamycin A is a potent antifungal agent and is used to control fungi in crop production. Validamycin A acts as a potent inhibitor of trehalase, an important enzyme in carbohydrate storage and ultilisation in fungi.Studies on validamycins, new antibiotics. I. Streptomyces hygroscopicus var. limoneus nov. var. validamycin - producing organism."
Purity by HPLC
Not less than 90%
Hazard Compound
Refer MSDS for accurate information.
Overview
"Validamycin A is the major analogue of a family of cyclitol disaccharides isolated from Streptomyces hygroscopicus var. limoneus by researchers at Takeda in 1970. Although commonly regarded as an aminoglycoside, validamycin shares little in common with conventional aminoglycosides such as streptomycin and gentamicin. Validamycin A is a potent antifungal agent and is used to control fungi in crop production. Validamycin A acts as a potent inhibitor of trehalase, an important enzyme in carbohydrate storage and ultilisation in fungi.Studies on validamycins, new antibiotics. I. Streptomyces hygroscopicus var. limoneus nov. var. validamycin - producing organism."

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