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Vemurafenib

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Product Code: CS-O-10915 API Research Use Only
Vemurafenib
Category
API
API Family
Vemurafenib
Product Code
CS-O-10915
Research Status
For Laboratory Use

Vemurafenib

Vemurafenib API
Stock Status: In Stock
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CAT No.
CS-O-10915
CAS No.
918504-65-1
Molecular Formula
C₂₃H₁₈ClF₂N₃O₃S
Molecular Weight
489.92
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal or Veterinary use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
918504-65-1
Product Code
CS-O-10915
M.F.
C₂₃H₁₈ClF₂N₃O₃S
M.W.
489.92
Smiles
O=C(C1=CNC2=NC=C(C=C21)C=3C=CC(Cl)=CC3)C=4C(F)=CC=C(NS(=O)(=O)CCC)C4F
Category
API
API Family
Vemurafenib
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
N-[3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4- difluorophenyl]propane-1-sulfonamide
References
"Halaban; R, et al,: Pigm, Cell, Melonoma Res,; 23; 190 (2010); Yang; H, et al,: Cancer Res,; 70; 5518 (2010); Comin-Anduix; B, et al,: Clin, Cancer Res,; 16; 6040 (2010);"
Synonyms
Zelboraf
Application Notes
"Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600."
Purity by HPLC
Not less than 95 %
Hazard Compound
Refer MSDS for accurate information.
Overview
"Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600."

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