Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Acalabrutinib, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Acalabrutinib impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Acalabrutinib-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Our Acalabrutinib-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Acalabrutinib Related Compounds
Stable Isotopes
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Acalabrutinib intermediate D4 | Stable Isotopes | CS-O-47504 | Not Available | Enquire |
| Acalabrutinib-d3 | Stable Isotopes | CS-T-94747 | 1420477-60-6(Unlabelled) | Enquire |
Metabolite
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| 2-methyl-4-oxo Acalabrutinib impurity | Metabolite | CS-O-45112 | 2412166-56-2 | Enquire |
Impurity
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| 1-Bromo-3-(2S)-2-pyrrolidinylimidazo[1,5-a]pyrazin-8-amine | Impurity | CS-O-55612 | 2097168-73-3 | Enquire |
| Acalabrutinib 1,5-Dibromo Impurity | Impurity | CS-O-60335 | ---- | Enquire |
| Acalabrutinib 1,6-Dibromo Impurity | Impurity | CS-O-60334 | ---- | Enquire |
| Acalabrutinib 6-Amide Impurity | Impurity | CS-O-57487 | 1420478-89-2 | Enquire |
| Acalabrutinib 8-Hydroxy impurity | Impurity | CS-O-37319 | Not Available | In Stock |
| Acalabrutinib chloro impurity | Impurity | CS-O-58389 | ---- | Enquire |
| Acalabrutinib Dimer Impurity 2 | Impurity | CS-O-56612 | 723260-09-1 | Enquire |
| Acalabrutinib Impurity 10 | Impurity | CS-O-60333 | ---- | Enquire |
| Acalabrutinib Impurity 11 | Impurity | CS-O-41255 | 2490433-97-9 | Enquire |
| Acalabrutinib Impurity 12 | Impurity | CS-EO-01300 | ---- | Enquire |
| Acalabrutinib Impurity 13 | Impurity | CS-EO-01301 | ---- | Enquire |
| Acalabrutinib Impurity 23 | Impurity | CS-O-43802 | Not Available | Enquire |
| Acalabrutinib Impurity 24 | Impurity | CS-O-43803 | 2198380-46-8 | Enquire |
| Acalabrutinib Impurity 9 | Impurity | CS-O-60332 | ---- | Enquire |
| Acalabrutinib R-Isomer | Impurity | CS-EO-02265 | 1952316-43-6 | In Stock |
| Acalabrutinib-3,4-dihydropyrrole | Impurity | CS-O-55143 | ---- | Enquire |
| N-benzylacalabromide | Impurity | CS-O-55144 | ---- | Enquire |
| 1-[(Benzyloxy)carbonyl]pyrrolidine-2-carboxylic acid | Impurity | CS-M-25981 | 1148-11-4 | Enquire |
| Acalabrutinib Acetyl impurity | Impurity | CS-O-37317 | Not Available | Enquire |
| Acalabrutinib Diamide impurity | Impurity | CS-O-37318 | Not Available | Enquire |
| Acalabrutinib Impurity 21 | Impurity | CS-RS-00022 | 1418307-18-2 | Enquire |
| Acalabrutinib Impurity 22 | Impurity | CS-RS-00023 | 1420478-87-0 | Enquire |
| Acalabrutinib Impurity 7 | Impurity | CS-EO-00712 | 2180911-32-2 | Enquire |
Fine Chemicals
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (5-Chloropyrazin-2-yl)methanamine | Fine Chemicals | CS-MM-60595 | 1060814-53-0 | Enquire |
| Benzyl (2S)-2-{[(3-chloro-2-pyrazinyl)methyl]carbamoyl}-1-py... | Fine Chemicals | CS-RS-00021 | 1418307-17-1 | Enquire |
Nitrosamine
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (S)-1-bromo-3-(1-nitrosopyrrolidin-2-yl)imidazo[1,5-a]pyrazi... | Nitrosamine | CS-O-60468 | ---- | Enquire |
| (S)-1-bromo-8-chloro-3-(1-nitrosopyrrolidin-2-yl)imidazo[1,5... | Nitrosamine | CS-O-60469 | ---- | Enquire |
| (S)-4-(8-amino-3-(1-nitrosopyrrolidin-2-yl)imidazo[1,5-a]pyr... | Nitrosamine | CS-O-53322 | ----- | Enquire |
| (S)-8-chloro-3-(1-nitrosopyrrolidin-2-yl)imidazo[1,5-a]pyraz... | Nitrosamine | CS-O-60470 | ---- | Enquire |
| (S)-N-((3-chloropyrazin-2-yl)methyl)-1-nitrosopyrrolidine-2-... | Nitrosamine | CS-O-60471 | ---- | Enquire |
| N-Nitroso-Des-1-oxo-2-butyn-Acalabrutinib | Nitrosamine | CS-O-48941 | ---- | Enquire |
Building Blocks
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (3,5-Dichloropyrazin-2-yl)methanamine Hydrochloride | Building Blocks | CS-EO-03286 | 2089319-25-3 | Enquire |
| (5-Chloropyrazin-2-yl)methanamine Hydrochloride | Building Blocks | CS-EO-03285 | 1794737-26-0 | Enquire |
Therapeutic
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Acalabrutinib | Therapeutic | CS-AV-00045 | 1420477-60-6 | In Stock |
| Acalabrutinib Impurity 26 | Therapeutic | CS-EM-03233 | 1420478-88-1 | Enquire |