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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Biotin, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Biotin impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Biotin-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Biotin Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
1-O-(4,4'-Dimethoxytrityl)-3-O-(N-biotinyl-3-aminopropyl)gly... Stable Isotopes CS-T-96416 131622-83-8(Unlabelled) Enquire
5-[2-Biotinylamidoethyl]-dithiopropionamido]-3,7-diaza-4,6-d... Stable Isotopes CS-T-96422 Not Available Enquire
6-[2-Biotinylamidoethyl]-dithiopropionamido]-4,8-diaza-5,7-d... Stable Isotopes CS-T-96421 Not Available Enquire
6-[2-Biotinylamidoethyl]-dithiopropionamido]-5,9-diaza-6,8-d... Stable Isotopes CS-T-96420 Not Available Enquire
6-N-Biotinylaminohexyl Isopropyl-d7 Phosphorofluoridate, Hem... Stable Isotopes CS-T-96419 1246812-28-1 Enquire
Biotin-2′,2′,3′,3′-d4 Stable Isotopes CS-BX-00918 1799489-82-9 Enquire
Biotin-d2 Stable Isotopes CS-O-11977 1217481-41-8 In Stock
Biotinyl Cystamine-d4 Stable Isotopes CS-T-96417 1322625-65-9 Enquire
D-Biotin-d2 (pentanoic-2,2-d2) Stable Isotopes CS-C-01433 58-85-5 (Unlabelled) Enquire
erythro-ω-Amino Sphingosine Biotinamide-d4 Stable Isotopes CS-T-96423 Not Available Enquire
N’-(13-Iodoacetamido-4,7,10-trioxatridecanyl-2,2’,3,3’,11,11... Stable Isotopes CS-T-96415 Not Available Enquire
N-Biotinyl-3-aminopropyl Solketal-d5 Stable Isotopes CS-T-96418 Not Available Enquire
Sulfo-NHS-LC-Biotin-D10 Stable Isotopes CS-T-104065 191671-46-2(unlablled) Enquire
VITAMIN B7 (BIOTIN) (3',3',4',4'-D4) Stable Isotopes CS-TA-30496 1217850-77-5 Enquire
13-Amino-4,7,10-trioxatridecanyl-2,2’,3,3’,11,11’,12,12’-d8)... Stable Isotopes CS-T-66305 1217717-09-3 Enquire
Biotin 13C5 Stable Isotopes CS-O-34760 58-85-5 (Unlabeled) Enquire
Biotin sulfoxide 13C5 Stable Isotopes CS-EK-02244 3376-83-8 unlabeled Enquire
FP-Biotin-d4 Stable Isotopes CS-T-76196 1219356-78-1 Enquire


API

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
D-Biotin API CS-P-00358 58-85-5 In Stock
Biotin HPDP API CS-T-49126 129179-83-5 Enquire
Biotin Hydrazide API CS-T-49127 66640-86-6 Enquire
Biotinyl-Amylin (human) API CS-AX-00025 1678415-18-3 Enquire
Biotinyl-Amylin (mouse, rat) API CS-AX-00026 1678414-88-4 Enquire
Fluorescein Biotin API CS-T-77664 134759-22-1 Enquire
FP-Biotin API CS-T-55073 259270-28-5 Enquire
N-Biotinyl p-Aminophenyl Arsinic Acid API CS-T-49138 212391-23-6 Enquire
Sulfo-NHS-Biotin API CS-T-61534 119616-38-5 Enquire


Metabolite

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Biotin Sulfoxide Metabolite CS-P-00736 23015-53-4 Enquire
Biotinylated isoxazole Metabolite CS-O-43690 1377605-22-5 Enquire


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Biotin EP Impurity C (Diamino Biotin) Impurity CS-T-52409 22342-46-7 Enquire
Biotin EP Impurity C Dihydrochloride Impurity CS-O-59506 22342-46-7 (Freebase) In Stock
Biotin EP Impurity E (Mixture of Isomers) Impurity CS-P-07294 76335-62-1 and 57229-92-2 Enquire
Biotin-Vitamin B7 Impurity CS-O-08437 58-85-5 In Stock
D-Biotin Dimer Acid Impurity CS-T-49124 1163708-46-0 In Stock
Succinimidyl-6-[6-(biotinamido)caproyl]caproylate Impurity CS-T-61478 89889-52-1 Enquire
(-)-Biotin Sulfoxide Impurity CS-T-49115 3376-83-8 Enquire
(+)-Biotin (+)-Sulfoxide Impurity CS-T-49116 10406-89-0 Enquire
(+)-Biotin 4-Amidobenzoic Acid, Sodium Salt Impurity CS-T-06529 102418-74-6 Enquire
(+)-Biotin-PFP-ester Impurity CS-DL-00795 120550-35-8 Enquire
(+/-)-Epiallobiotin Impurity CS-O-33618 68225-55-8 Enquire
1,17-Bisbiotinylamino-3,6,9,12,15-pentaoxaheptadecane (>90%) Impurity CS-T-49205 440680-87-5 Enquire
1-O-(4,4’-Dimethoxytrityl)-3-O-(N-biotinyl-3-aminopropyl)gly... Impurity CS-T-91148 131622-83-8 Enquire
2,7-Bis(alloxycarbonylamino)-9-(biotinylaminoethylamino)acri... Impurity CS-T-49186 1219125-65-1 Enquire
2-[2-[2-[2-[6-(Biotinylaminohexanoyl]aminoethoxy]ethoxy]etho... Impurity CS-T-49134 207971-23-1 Enquire
3-[[2-(Biotinamido)ethyl]dithio]propionic Acid 4'-(Hydroxyme... Impurity CS-T-49119 1255087-87-6 Enquire
3-[2-N-(Biotinyl)aminoethyldithio]propanoic Acid Impurity CS-T-06562 104582-29-8 Enquire
5-Oxohexyl Biotin Impurity CS-T-38446 1160188-05-5 Enquire
6-[4'-N-(biotinylaminopropyl-NHCOCH2-PEG2-acetyl)-aminopheny... Impurity CS-T-49139 1522299-17-7 Enquire
6-N-Biotinylaminohexyl Isopropyl Hydrogenphosphonate Impurity CS-T-06572 224583-37-3 Enquire
6-N-Biotinylaminohexyl Isopropyl Phosphorofluoridate, Hemihy... Impurity CS-T-49136 353754-93-5 Enquire
9-Methyl Biotin Impurity CS-T-58005 415725-35-8 Enquire
Acriflavin-Biotin Conjugate Impurity CS-T-47438 1041387-90-9 Enquire
Allobiotin Impurity CS-ED-00357 5652-41-5 Enquire
Beta GlcNAc-PEG3-Biotin Impurity CS-AI-00023 Not Available Enquire
Beta Glc-PEG3-Biotin Impurity CS-AI-00024 Not Available Enquire
Biotin Diacid Impurity CS-T-06538 57671-79-1 Enquire
Biotin Impurity 1 Impurity CS-P-07292 26339-40-2 Enquire
Biotin Impurity 3 Impurity CS-T-47790 111790-37-5 Enquire
Biotin Impurity 4 Impurity CS-P-02236 111822-45-8 Enquire
Biotin Impurity C DiHydrochloride Impurity CS-P-07293 412308-26-0 (free base) Enquire
Biotin-11-dUTP Impurity CS-T-49123 1221498-88-9 Enquire
Biotinamidocaproate Tobramycin Amide Impurity CS-T-49118 419573-19-6 Enquire
Biotinyl Tobramycin Amide Impurity CS-T-49154 419573-18-5 Enquire
Biotinyl-Amyloid β-Protein (1-42) Impurity CS-AX-00011 1802086-20-9 Enquire
BNP, D-Biotin 4-nitrophenyl ester Impurity CS-DL-00558 33755-53-2 Enquire
cis-(-)-1,3-Dibenzylhexahydro-2-oxo-1H-thieno[3,4-d]imidazol... Impurity CS-T-89029 33607-60-2 Enquire
Epibiotin Impurity CS-O-33617 4375-00-2 Enquire
erythro-ω-Amino Sphingosine Biotinamide Impurity CS-T-66201 752987-57-8 Enquire
erythro-ω-Amino Sphingosine Biotinamide Phosphate Impurity CS-T-66302 799812-63-8 Enquire
N-(15,16-Dihydroxy-4,7,10,13-tetraoxahexadecyl-D-(+)-biotina... Impurity CS-T-91210 869354-59-6 Enquire
N-(2-Aminoethyl)-N’-(2-Sulfothioacetamid)biotinamide, Sodium... Impurity CS-T-65633 1330264-29-3 Enquire
N1-(4-(t-Butyl)benzoyl)-D-(+)biotin 2-Nitrophenyl Ester Impurity CS-T-69368 869354-61-0 Enquire
N1-(Dimethoxytrityl)-D-(+)biotin 2-Nitrophenyl Ester Impurity CS-T-91456 869354-63-2 Enquire
N2-t-Boc-N6-(biotinamido-6-N-caproylamido)lysine Impurity CS-T-07472 102910-26-9 Enquire
N-Biotinyl Dopamine Impurity CS-T-49148 241142-94-9 Enquire
N-Biotinyl Glycine Impurity CS-T-49150 160390-90-9 Enquire
N-Biotinyl-12-aminododecanoic Acid Impurity CS-T-06554 135447-73-3 Enquire
N-Biotinyl-12-aminododecanoyltobramycin Amide Impurity CS-T-49130 419573-20-9 Enquire
N-Biotinylcaproic Acid Impurity CS-T-06586 72040-64-3 Enquire
N-Biotinylcaproylaminocaproic Acid Impurity CS-T-06590 89889-51-0 Enquire
N-Biotinylcaproylaminocaproylaminoethyl Methanethiosulfonate Impurity CS-T-49144 1038749-81-3 Enquire
N-Boc-Biotinylethylenediamine Impurity CS-T-07475 225797-46-6 Enquire
N-d-Biotinyl-7-amino-4-methylcoumarin Impurity CS-T-49137 191223-35-5 Enquire
N-Succinimido (+)-Biotin Impurity CS-T-61471 35013-72-0 Enquire
Sulfosuccinimidyl 3-[[2-(Biotinamido)ethyl] dithio]propionat... Impurity CS-T-61540 325143-98-4 Enquire


Intermediate

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Norbiotin Intermediate CS-O-49613 669-72-7 Enquire


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
1-Thioglycerol Fine Chemicals CS-T-44188 96-27-5 In Stock
5-(Biotinamido)pentylamine Fine Chemicals CS-T-49120 115416-38-1 Enquire
6-N-Biotinylaminohexanol Fine Chemicals CS-T-49133 106451-92-7 Enquire
ATP-polyamine-biotin Fine Chemicals CS-ZE-01916 1800401-93-7 Enquire
Biotin 5-Bromopentylamide Fine Chemicals CS-T-49121 1217605-72-5 Enquire
Biotin-4-Fluorescein Fine Chemicals CS-T-49125 1032732-74-3 Enquire
DL-Biotin Fine Chemicals CS-O-33616 22377-59-9 Enquire
N-Biotinyl-1,6-hexanediamine Fine Chemicals CS-T-49149 65953-56-2 Enquire


Nitrosamine

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Nitrosobiotin Nitrosamine CS-ED-01850 56859-26-8 In Stock


Secondary Standards

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Biotin Secondary Standards CS-SS-24253-1GM 58-85-5 Enquire


Peptide

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
BIOTINYL-EPSILONAHX-CYS-LYS-SER-HYP-GLY-SER-SER-CYS-SER-HYP-... Peptide CS-O-55472 151928-23-3 Enquire
Biotinyl-GHK tripeptide Peptide CS-O-45006 299157-54-3 In Stock
ATP-polyamine-biotin Peptide CS-O-39887 1800401-93-7 Enquire
Biotinyl-eAhx-Amyloid β-Protein (1-40) Peptide CS-AX-00005 Not Available Enquire
Biotinyl-eAhx-Amyloid β-Protein (1-42) Peptide CS-AX-00012 1872440-40-8 Enquire


Polymers

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Poly(1,2-butadiene)-b-poly(ethylene oxide), w-Biotin-termina... Polymers CS-PM-01311 Not Available Enquire
Poly(ethylene glycol), (a-trimethoxysilyl, w-Biotinyl)-termi... Polymers CS-PM-01106 Not Available Enquire
Poly(ethylene glycol), a,w-bis(Biotinyl)-terminated Polymers CS-PM-01075 Not Available Enquire
Poly(ethylene oxide) methyl ether, w-Biotinyl-terminated Polymers CS-PM-01116 Not Available Enquire


Biochemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
D-Biotin for tissue culture, 99% Biochemicals CS-SR-00258 58-85-5 Enquire


Building Blocks

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2-[Na-Benzoylbenzoicamido-N6-(6-biotinamidocaproyl)-L-lysiny... Building Blocks CS-T-48718 910036-44-1 Enquire
Ibrutinib-biotin Building Blocks CS-ZB-30717 1599432-18-4 Enquire
N-Biotinyl-N-(N-Boc-S-trityl)cysteinyl Ethylenediamine Building Blocks CS-T-49143 508234-94-4 Enquire
N-Biotinyl-N-Boc-1,6-hexanediamine Building Blocks CS-T-49142 153162-70-0 Enquire
N-Fmoc-N\\-Biotinyl-D-lysine Building Blocks CS-DV-03655 110990-09-5 Enquire


Carbohydrates

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
GM1aCer d18:1/18:0-Biotin (Galb1,3GalNAcb1,4(Neu5Aca2,3)Galb... Carbohydrates CS-O-50898 2770684-25-6 Enquire
A-Antigen-Cer d18:1/18:0-Biotin (GalNAca1,3(Fuca1,2)Galb1,4G... Carbohydrates CS-O-50919 Not Available Enquire
B-Antigen-Cer d18:1/18:0-Biotin (Gala1,3(Fuca1,2)Galb1,4Glcb... Carbohydrates CS-O-50920 Not Available Enquire
FucGM1Cer d18:1/18:0-Biotin ((Fuca1,2)Galb1,3GalNAcb1,4(Neu5... Carbohydrates CS-O-50903 Not Available Enquire
GB4Cer d18:1/18:0-Biotin (GalNAcb1,3Gala1,4Galb1,4GlcbCerami... Carbohydrates CS-O-50909 Not Available Enquire
GB5Cer d18:1/18:0-Biotin (Galb1,3GalNAcb1,3Gala1,4Galb1,4Glc... Carbohydrates CS-O-50910 Not Available Enquire
GD1bCer d18:1/18:0-Biotin (Galb1,3GalNAcb1,4(Neu5Aca2,8Neu5A... Carbohydrates CS-O-50906 Not Available Enquire
GD2Cer d18:1/18:0-Biotin (GalNAcb1,4(Neu5Aca2,8Neu5Aca2,3)Ga... Carbohydrates CS-O-50905 Not Available Enquire
GD3Cer d18:1/18:0-Biotin (Neu5Aca2,8Neu5Aca2,3Galb1,4GlcbCer... Carbohydrates CS-O-50904 Not Available Enquire
GloboHCer d18:1/18:0-Biotin ((Fuca1,2)Galb1,3GalNAcb1,3Gala1... Carbohydrates CS-O-50911 Not Available Enquire
GM1bCer d18:1/18:0-Biotin ((Neu5Aca2,3)Galb1,3GalNAcb1,4Galb... Carbohydrates CS-O-50902 Not Available Enquire
GM2Cer d18:1/18:0-Biotin (GalNAcb1,4(Neu5Aca2,3)Galb1,4GlcbC... Carbohydrates CS-O-50899 Not Available Enquire
GM3Cer d18:1/18:0-Biotin ((Neu5Aca2,3)Galb1,4GlcbCeramide-Bi... Carbohydrates CS-O-50900 Not Available Enquire
GT3Cer d18:1/18:0-Biotin (Neu5Aca2,8Neu5Aca2,8Neu5Aca2,3Galb... Carbohydrates CS-O-50908 Not Available Enquire
GT3Cer d18:1/18:0-Biotin (Neu5Aca2,8Neu5Aca2,8Neu5Aca2,3Galb... Carbohydrates CS-O-50907 Not Available Enquire
H-Antigen-Cer d18:1/18:0-Biotin ((Fuca1,2)Galb1,4GlcbCeramid... Carbohydrates CS-O-50918 Not Available Enquire
iGB3Cer d18:1/18:0-Biotin (Gala1,3Galb1,4GlcbCeramide-Biotin... Carbohydrates CS-O-50913 Not Available Enquire
iGB4Cer d18:1/18:0-Biotin (GalNAcb1,3Gala1,3Galb1,4GlcbCeram... Carbohydrates CS-O-50914 Not Available Enquire
iGB5Cer d18:1/18:0-Biotin (Galb1,3GalNAcb1,3Gala1,3Galb1,4Gl... Carbohydrates CS-O-50915 Not Available Enquire
iGloboHCer d18:1/18:0-Biotin ((Fuca1,2)Galb1,3GalNAcb1,3Gala... Carbohydrates CS-O-50916 Not Available Enquire
LacCer d18:1/18:0-Biotin (Galb1,4GlcbCeramide-Biotin) Carbohydrates CS-O-50901 Not Available Enquire
Lc3Cer d18:1/18:0-Biotin (GlcNAcb1,3Galb1,4GlcbCeramide-Biot... Carbohydrates CS-O-50921 Not Available Enquire
Lc4Cer d18:1/18:0-Biotin (Galb1,3GlcNAcb1,3Galb1,4GlcbCerami... Carbohydrates CS-O-50923 Not Available Enquire
LewisaCer d20:1/24:1-Biotin (Galb1,3(Fuca1,4)GlcNAcb1,3Galb1... Carbohydrates CS-O-50925 Not Available Enquire
LewisxCer d18:1/18:0-Biotin (Galb1,4(Fuca1,3)GlcNAcb1,3Galb1... Carbohydrates CS-O-50924 Not Available Enquire
Neu5Gca2-3Lea-sp-biotin Carbohydrates CS-O-51147 Not Available Enquire
nLc4Cer d18:1/18:0-Biotin (Galb1,4GlcNAcb1,3Galb1,4GlcbCeram... Carbohydrates CS-O-50922 Not Available Enquire
Sialyl-iGB5Cer d18:1/18:0-Biotin ((Neu5Aca2,3)Galb1,3GalNAcb... Carbohydrates CS-O-50917 Not Available Enquire
SSEA-4 d18:1/18:0-Biotin ((Neu5Aca2,3)Galb1,3GalNAcb1,3Gala1... Carbohydrates CS-O-50912 Not Available Enquire