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Empagliflozin Related Compounds

API

COMPOUNDCATEGORYCAT. No.CAS. No.ACTIONS
X Structure - Empagliflozin

Empagliflozin
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API CS-O-11249 864070-44-0
X Structure - Empagliflozin Methyl Impurity

Empagliflozin Methyl Impurity
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API CS-O-33488 333359-90-3

Building Blocks

COMPOUNDCATEGORYCAT. No.CAS. No.ACTIONS
X Structure - (S)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

(S)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
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Building Blocks CS-O-45582 112052-11-6

Fine Chemicals

COMPOUNDCATEGORYCAT. No.CAS. No.ACTIONS
X Structure - (3S,8R)-1,6-dioxecane-3,8-diol

(3S,8R)-1,6-dioxecane-3,8-diol
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Fine Chemicals CS-O-54741 2839101-08-3
X Structure - (5-bromo-2-chlorophenyl)(2-fluorophenyl)methanone

(5-bromo-2-chlorophenyl)(2-fluorophenyl)methanone
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Fine Chemicals CS-O-33468 1715629-30-3
X Structure - (7S)-7-Hydroxy-1,4-dioxocane-2-ethanol

(7S)-7-Hydroxy-1,4-dioxocane-2-ethanol
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Fine Chemicals CS-O-54743 2820386-27-2
X Structure - 2,2'-(1,4-dioxane-2,5-diyl)diethanol

2,2'-(1,4-dioxane-2,5-diyl)diethanol
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Fine Chemicals CS-O-54742 854841-54-6
X Structure - 4-Bromo-1-chloro-2-(4-fluorobenzyl)benzene

4-Bromo-1-chloro-2-(4-fluorobenzyl)benzene
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Fine Chemicals CS-O-36787 1628918-33-1
X Structure - 4-Hydroxybutanoic acid lactone

4-Hydroxybutanoic acid lactone
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Fine Chemicals CS-O-13298 96-48-0

Glucuronide

COMPOUNDCATEGORYCAT. No.CAS. No.ACTIONS
X Structure - Empagliflozin 2-O-Glucuronide

Empagliflozin 2-O-Glucuronide
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Glucuronide CS-O-15444 ----
X Structure - Empagliflozin 4-O-Glucuronide

Empagliflozin 4-O-Glucuronide
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Glucuronide CS-O-12061 Not Available
X Structure - Empagliflozin-3-O-beta-D-Glucuronide

Empagliflozin-3-O-beta-D-Glucuronide
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Glucuronide CS-O-15445 Not Available
X Structure - Empagliflozin-6-Glucuronide

Empagliflozin-6-Glucuronide
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Glucuronide CS-O-15446 ----

Impurity

COMPOUNDCATEGORYCAT. No.CAS. No.ACTIONS
X Structure - (1R,2S,3S,4R)-1-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)hexane-1,2,3,4,6-pentaol

(1R,2S,3S,4R)-1-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)ox...
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Impurity CS-O-41444 Not Available
X Structure - (2,5-dibromophenyl)(4-fluorophenyl)methanone

(2,5-dibromophenyl)(4-fluorophenyl)methanone
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Impurity CS-O-54155 1713015-56-5
X Structure - (2-bromo-6-chlorophenyl)(4-fluorophenyl)methanone

(2-bromo-6-chlorophenyl)(4-fluorophenyl)methanone
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Impurity CS-O-54153 1997260-73-7
X Structure - (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-(4-iodo-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)tetra

(2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-(4-iodo-3-(4-(((S)-tetr...
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Impurity CS-O-35330 Not Available
X Structure - (2S,3R,4R,5S,6R)-2-(4-chloro-3-(2-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tet

(2S,3R,4R,5S,6R)-2-(4-chloro-3-(2-(((S)-tetrahydrofuran-3-yl...
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Impurity CS-O-35328 Not Available
X Structure - (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-((((R)-tetrahydrof

(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl...
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Impurity CS-O-36229 Not Available
X Structure - (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)-5-

(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl...
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Impurity CS-O-36228 Not Available
X Structure - (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-isopropoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,

(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-isopropoxybenzyl)phenyl)-6...
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Impurity CS-O-35329 946525-39-9
X Structure - (3-bromo-2-chlorophenyl)(4-fluorophenyl)methanone

(3-bromo-2-chlorophenyl)(4-fluorophenyl)methanone
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Impurity CS-O-54152 1919893-83-6
X Structure - (3R)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran

(3R)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydro...
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Impurity CS-DV-00165 915095-90-8
X Structure - (3R,4R,5S)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)

(3R,4R,5S)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)b...
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Impurity CS-O-33293 Not Available
X Structure - (4-bromo-2-chlorophenyl)(4-fluorophenyl)methanone

(4-bromo-2-chlorophenyl)(4-fluorophenyl)methanone
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Impurity CS-O-54154 1157263-84-7
X Structure - (4S)-4-Hydroxyphenylmethoxy-2-methoxy Empagliflozin

(4S)-4-Hydroxyphenylmethoxy-2-methoxy Empagliflozin
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Impurity CS-O-48957 2253771-11-6
X Structure - (5-Bromo-2-chlorophenyl)(2-methoxyphenyl)methanone

(5-Bromo-2-chlorophenyl)(2-methoxyphenyl)methanone
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Impurity CS-O-60253 1771251-94-5
X Structure - (5-bromo-2-chlorophenyl)(3-fluorophenyl)methanone

(5-bromo-2-chlorophenyl)(3-fluorophenyl)methanone
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Impurity CS-O-54156 1712958-06-9
X Structure - (R)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-8-((3,4,5,6-tetrahydropyridin-3-yl)amino)-1H-purine-2,6(3H,7H)-dione

(R)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)m...
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Impurity CS-O-54799 ----
X Structure - (R,R)-Empagliflozin

(R,R)-Empagliflozin
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Impurity CS-O-15985 2452301-42-5
X Structure - (S)-3-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenoxy)tetrahydrofuran

(S)-3-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)p...
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Impurity CS-O-53974 ----
X Structure - (S)-Empagliflozin L-glucitol tetraacetate

(S)-Empagliflozin L-glucitol tetraacetate
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Impurity CS-O-59403 ----
X Structure - (S)-Empagliflozin Peracetyl

(S)-Empagliflozin Peracetyl
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Impurity CS-O-52113 1620758-27-1
X Structure - (S)-Empagliflozin Peracetyl Impurity

(S)-Empagliflozin Peracetyl Impurity
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Impurity CS-O-12071 915095-99-7
X Structure - 1-Hydroxy Empagliflozin

1-Hydroxy Empagliflozin
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Impurity CS-T-63072 1279691-35-8
X Structure - 1-Methoxy Empagliflozin

1-Methoxy Empagliflozin
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Impurity CS-O-12086 1279691-36-9
X Structure - 1-Methoxy Empagliflozin

1-Methoxy Empagliflozin
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Impurity CS-O-14886 915095-96-4
X Structure - 1-Methoxy-Empagliflozin Tetraacetoxy

1-Methoxy-Empagliflozin Tetraacetoxy
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Impurity CS-O-39363 1620758-21-5
X Structure - 2,3,4,6-Tetra-O-(trimethylsilyl)-D-glucono-1,5-lactone

2,3,4,6-Tetra-O-(trimethylsilyl)-D-glucono-1,5-lactone
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Impurity CS-O-32367 32384-65-9
X Structure - 2-Chlorobenzyl Butane Empagliflozin

2-Chlorobenzyl Butane Empagliflozin
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Impurity CS-O-52107 Not Available
X Structure - 2-Hydroxy Empagliflozin

2-Hydroxy Empagliflozin
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Impurity CS-O-35331 2452301-34-5
X Structure - 3,3'-bis(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)-1,1'-biphenyl

3,3'-bis(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)-1,1'-biphe...
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Impurity CS-O-52108 Not Available
X Structure - 3'-Epi Empagliflozin

3'-Epi Empagliflozin
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Impurity CS-O-12062 864070-43-9
X Structure - 3-Epi Empagliflozin (R)-Furanose

3-Epi Empagliflozin (R)-Furanose
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Impurity CS-O-14891 ----
X Structure - 3-Epi Empagliflozin (S)-Furanose

3-Epi Empagliflozin (S)-Furanose
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Impurity CS-O-14890 2452301-07-2
X Structure - 3-Epi Empagliflozin 6-(R)-tetrahydrofuran-3-yl Impurity

3-Epi Empagliflozin 6-(R)-tetrahydrofuran-3-yl Impurity
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Impurity CS-O-59264 ----
X Structure - 3-Epi Empagliflozin tetra Acetyl impurity

3-Epi Empagliflozin tetra Acetyl impurity
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Impurity CS-O-52240 915095-98-6
X Structure - 4-chloro-1-(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)phenyl)butan-1-one

4-chloro-1-(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)ph...
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Impurity CS-O-49651 Not Available
X Structure - Dichloro Empagliflozin Impurity

Dichloro Empagliflozin Impurity
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Impurity CS-O-60583 ----
X Structure - Empagliflozin 4-Bromo Impurity

Empagliflozin 4-Bromo Impurity
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Impurity CS-O-52103 Not Available
X Structure - Empagliflozin 5-Bromo Hydroxy Analog

Empagliflozin 5-Bromo Hydroxy Analog
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Impurity CS-O-36785 1800196-43-3
X Structure - Empagliflozin Acetyl Impurity

Empagliflozin Acetyl Impurity
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Impurity CS-EO-00244 1079083-63-8
X Structure - Empagliflozin Aglycon Phenol

Empagliflozin Aglycon Phenol
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Impurity CS-O-52106 2770456-61-4
X Structure - Empagliflozin Alpha Isomer

Empagliflozin Alpha Isomer
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Impurity CS-O-14884 1620758-33-9
X Structure - Empagliflozin Bromo Impurity

Empagliflozin Bromo Impurity
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Impurity CS-EO-00246 ----
X Structure - Empagliflozin Bromo Phenoxy Ether Impurity

Empagliflozin Bromo Phenoxy Ether Impurity
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Impurity CS-O-61532 ----
X Structure - Empagliflozin Des bromomethoxy

Empagliflozin Des bromomethoxy
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Impurity CS-O-43347 Not Available
X Structure - Empagliflozin Destetrahydrofuran Impurity

Empagliflozin Destetrahydrofuran Impurity
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Impurity CS-O-12074 864070-37-1
X Structure - Empagliflozin Dichloro impurity

Empagliflozin Dichloro impurity
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Impurity CS-O-49268 2760767-62-0
X Structure - Empagliflozin diiodo Impurity

Empagliflozin diiodo Impurity
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Impurity CS-O-59261 ----
X Structure - Empagliflozin Dimer Impurity

Empagliflozin Dimer Impurity
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Impurity CS-O-12070 2864810-38-6
X Structure - Empagliflozin Dimer impurity-1

Empagliflozin Dimer impurity-1
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Impurity CS-O-54832 ----
X Structure - Empagliflozin Dimer impurity-2

Empagliflozin Dimer impurity-2
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Impurity CS-O-54833 ----
X Structure - Empagliflozin Dimethoxy Impurity

Empagliflozin Dimethoxy Impurity
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Impurity CS-O-43177 1800196-50-2
X Structure - Empagliflozin Diol impurity (S-Isomer)

Empagliflozin Diol impurity (S-Isomer)
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Impurity CS-EO-02027 2452301-18-5
X Structure - Empagliflozin Enantiomer Impurity

Empagliflozin Enantiomer Impurity
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Impurity CS-O-14885 ----
X Structure - Empagliflozin Ethylene Glycol Analog

Empagliflozin Ethylene Glycol Analog
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Impurity CS-O-59921 ----
X Structure - Empagliflozin Impurity 10

Empagliflozin Impurity 10
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Impurity CS-O-59251 2194590-02-6
X Structure - Empagliflozin Impurity 15

Empagliflozin Impurity 15
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Impurity CS-O-59253 2452301-15-2
X Structure - Empagliflozin Impurity 2

Empagliflozin Impurity 2
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Impurity CS-O-14887 ----
X Structure - Empagliflozin Impurity 22

Empagliflozin Impurity 22
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Impurity CS-O-59248 2452301-22-1
X Structure - Empagliflozin Impurity 26

Empagliflozin Impurity 26
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Impurity CS-EO-02866 1620758-25-9
X Structure - Empagliflozin Impurity 40

Empagliflozin Impurity 40
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Impurity CS-EO-03953 2744280-76-8
X Structure - Empagliflozin Impurity 46

Empagliflozin Impurity 46
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Impurity CS-O-33641 Not Available
X Structure - Empagliflozin Impurity 5

Empagliflozin Impurity 5
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Impurity CS-EO-01851 1800196-46-6
X Structure - Empagliflozin Impurity 50

Empagliflozin Impurity 50
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Impurity CS-O-38275 1800196-45-5
X Structure - Empagliflozin Impurity 52

Empagliflozin Impurity 52
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Impurity CS-P-08724 Not Available
X Structure - Empagliflozin Impurity 57

Empagliflozin Impurity 57
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Impurity CS-P-09230 2262435-19-6
X Structure - Empagliflozin Impurity 61

Empagliflozin Impurity 61
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Impurity CS-O-46430 1620758-30-6
X Structure - Empagliflozin Impurity 62

Empagliflozin Impurity 62
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Impurity CS-P-08723 Not Available
X Structure - Empagliflozin Impurity 74

Empagliflozin Impurity 74
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Impurity CS-O-59255 2452301-19-6
X Structure - Empagliflozin Impurity 8

Empagliflozin Impurity 8
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Impurity CS-O-59256 2452301-12-9
X Structure - Empagliflozin Impurity 80

Empagliflozin Impurity 80
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Impurity CS-O-54798 2452301-17-4
X Structure - Empagliflozin Impurity 82

Empagliflozin Impurity 82
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Impurity CS-P-09139 2452301-16-3
X Structure - Empagliflozin Impurity 97

Empagliflozin Impurity 97
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Impurity CS-O-57426 ----
X Structure - Empagliflozin impurity B

Empagliflozin impurity B
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Impurity CS-AQ-00156 Not Available
X Structure - Empagliflozin impurity C

Empagliflozin impurity C
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Impurity CS-AQ-00157 915095-94-2
X Structure - Empagliflozin impurity D

Empagliflozin impurity D
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Impurity CS-AQ-00158 Not Available
X Structure - Empagliflozin Impurity E

Empagliflozin Impurity E
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Impurity CS-O-38789 Not Available
X Structure - Empagliflozin Impurity II

Empagliflozin Impurity II
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Impurity CS-O-37759 2517968-35-1
X Structure - Empagliflozin Iodo impurity

Empagliflozin Iodo impurity
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Impurity CS-O-49269 2458157-10-1
X Structure - Empagliflozin Iodo R-furan impurity

Empagliflozin Iodo R-furan impurity
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Impurity CS-O-49270 2305949-35-1
X Structure - Empagliflozin L- Glucono Diastereomer

Empagliflozin L- Glucono Diastereomer
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Impurity CS-EO-02097 Not Available
X Structure - Empagliflozin Methoxy Impurity

Empagliflozin Methoxy Impurity
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Impurity CS-EO-00245 872980-38-6
X Structure - Empagliflozin Methoxy Intermediate

Empagliflozin Methoxy Intermediate
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Impurity CS-O-44819 915095-95-3
X Structure - Empagliflozin Methoxy Sugar Dimer

Empagliflozin Methoxy Sugar Dimer
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Impurity CS-O-57210 ---
X Structure - Empagliflozin Methoxy Sugar Dimer-(S) Isomer

Empagliflozin Methoxy Sugar Dimer-(S) Isomer
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Impurity CS-O-59254 ----
X Structure - Empagliflozin Methyl Acetate

Empagliflozin Methyl Acetate
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Impurity CS-O-39572 2452301-09-4
X Structure - Empagliflozin MonoAcetyl Impurity

Empagliflozin MonoAcetyl Impurity
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Impurity CS-O-12072 Not Available
X Structure - Empagliflozin Monoiodo Impurity

Empagliflozin Monoiodo Impurity
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Impurity CS-O-59262 ----
X Structure - Empagliflozin Nosyl ester hydroxy furan impurity

Empagliflozin Nosyl ester hydroxy furan impurity
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Impurity CS-O-45061 2113708-53-3
X Structure - Empagliflozin Nosyl impurity

Empagliflozin Nosyl impurity
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Impurity CS-O-45062 Not Available
X Structure - Empagliflozin ortho iodo Impurity

Empagliflozin ortho iodo Impurity
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Impurity CS-O-59263 ----
X Structure - Empagliflozin Phenolic Acid

Empagliflozin Phenolic Acid
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Impurity CS-O-60516 ----
X Structure - Empagliflozin R/S-Furanose

Empagliflozin R/S-Furanose
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Impurity CS-T-92179 1620758-31-7 + 1620758-32-8
X Structure - Empagliflozin Racemic Mixture

Empagliflozin Racemic Mixture
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Impurity CS-O-46876 2452301-21-0
X Structure - Empagliflozin S-Furanose

Empagliflozin S-Furanose
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Impurity CS-O-14888 1620758-32-8
X Structure - Empagliflozin Silyl Impurity

Empagliflozin Silyl Impurity
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Impurity CS-O-41519 2819995-58-7
X Structure - Empagliflozin Sugar Dimer

Empagliflozin Sugar Dimer
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Impurity CS-O-12069 Not Available
X Structure - Empagliflozin Sulfonate Impurity

Empagliflozin Sulfonate Impurity
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Impurity CS-EO-01831 2514922-33-7
X Structure - Empagliflozin-2H-pyran-5-tetrahydrofuran-3-yl-oxy impurity

Empagliflozin-2H-pyran-5-tetrahydrofuran-3-yl-oxy impurity
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Impurity CS-O-33531 Not Available
X Structure - Empagliflozin-2H-pyran-6-tetrahydrofuran-3-yl-oxy methyl impurity

Empagliflozin-2H-pyran-6-tetrahydrofuran-3-yl-oxy methyl imp...
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Impurity CS-O-33532 Not Available
X Structure - Hydroxy empagliflozin

Hydroxy empagliflozin
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Impurity CS-O-33304 2137418-13-2

Intermediate

COMPOUNDCATEGORYCAT. No.CAS. No.ACTIONS
X Structure - (S)-3-(4-benzylphenoxy)tetrahydrofuran

(S)-3-(4-benzylphenoxy)tetrahydrofuran
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Intermediate CS-O-52105 Not Available
X Structure - 5-Bromo-2-chlorobenzoic Acid

5-Bromo-2-chlorobenzoic Acid
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Intermediate CS-T-08026 21739-92-4
X Structure - L-Glucono-1,5-lactone

L-Glucono-1,5-lactone
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Intermediate CS-O-10972 52153-09-0

Metabolite

COMPOUNDCATEGORYCAT. No.CAS. No.ACTIONS
X Structure - Deschloro Empagliflozin

Deschloro Empagliflozin
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Metabolite CS-O-12084 2452301-27-6

Secondary Standards

COMPOUNDCATEGORYCAT. No.CAS. No.ACTIONS
X Structure - Empagliflozin Secondary Standard

Empagliflozin Secondary Standard
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Secondary Standards CS-SS-26553-1GM 864070-44-0
X Structure - Empagliflozin Secondary Standard

Empagliflozin Secondary Standard
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Secondary Standards CS-SS-26553 864070-44-0

Stable Isotopes

COMPOUNDCATEGORYCAT. No.CAS. No.ACTIONS
X Structure - (1R)-1,5-Dihydroxyempagliflozin-d4

(1R)-1,5-Dihydroxyempagliflozin-d4
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Stable Isotopes CS-T-101080 Not Available
X Structure - 1,4-Anhydro-1,5-dihydroxy-3’’’-epi-empagliflozin-d4

1,4-Anhydro-1,5-dihydroxy-3’’’-epi-empagliflozin-d4
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Stable Isotopes CS-T-97796 Not Available
X Structure - 3’’’-Epi-Empagliflozin-d4

3’’’-Epi-Empagliflozin-d4
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Stable Isotopes CS-T-97546 Not Available
X Structure - Empagliflozin 13C6

Empagliflozin 13C6
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Stable Isotopes CS-EK-02754 Not Available
X Structure - Empagliflozin D6

Empagliflozin D6
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Stable Isotopes CS-O-49796 864070-44-0 (Unlabelled)
X Structure - Empagliflozin D8

Empagliflozin D8
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Stable Isotopes CS-O-14856 2714418-84-3
X Structure - Empagliflozin-d4 (Furan-D4)

Empagliflozin-d4 (Furan-D4)
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Stable Isotopes CS-T-95115 864070-44-0 (Unlabelled)

Therapeutic

COMPOUNDCATEGORYCAT. No.CAS. No.ACTIONS
X Structure - (+)-3-Hydroxy-1,2,3,4-Tetrahydrofuran

(+)-3-Hydroxy-1,2,3,4-Tetrahydrofuran
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Therapeutic CS-O-31977 86087-23-2
X Structure - (3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydro-furan

(3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydro...
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Therapeutic CS-O-32139 915095-89-5
X Structure - Empagliflozin impurity A

Empagliflozin impurity A
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Therapeutic CS-AQ-00155 1981470-48-7
X Structure - Empagliflozin Open Ring Impurity

Empagliflozin Open Ring Impurity
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Therapeutic CS-O-12058 1620758-34-0
X Structure - Empagliflozin R-Furanose

Empagliflozin R-Furanose
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Therapeutic CS-O-14889 1620758-31-7