Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Ibrutinib, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Ibrutinib impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Ibrutinib-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Our Ibrutinib-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Ibrutinib Related Compounds
Stable Isotopes
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (S)-Ibrutinib-d5 | Stable Isotopes | CS-T-100164 | 1553977-17-5 | Enquire |
| Ibrutinib-d4 | Stable Isotopes | CS-EO-02537 | Not Available | Enquire |
| Ibrutinib-d4 (Major) | Stable Isotopes | CS-T-100165 | Not Available | Enquire |
| Ibrutinib-d5 | Stable Isotopes | CS-O-13635 | 1553977-17-5 | In Stock |
| Ibrutinib-d5 Acetate | Stable Isotopes | CS-O-03390 | 1553977-17-5(Freebase) | In Stock |
| N-Boc-Ibrutinib-d4 | Stable Isotopes | CS-T-98827 | Not Available | Enquire |
| Dihydrodiol Ibrutinib D5 | Stable Isotopes | CS-O-13637 | 1226872-27-0 (Unlabeled) | Enquire |
API
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Ibrutinib | API | CS-T-29032 | 936563-96-1 | In Stock |
| Ibrutinib-Hemi Fumaric Acid | API | CS-EO-03613 | 936563-96-1 (Freebase) | Enquire |
| Remibrutinib | API | CS-ED-00614 | 1787294-07-8 | Enquire |
Metabolite
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Ibrutinib Metabolite M37 | Metabolite | CS-ED-02437 | 1654820-87-7 | In Stock |
| Dihydrodiol Rac-Ibrutinib | Metabolite | CS-O-13636 | 1226872-27-0 | Enquire |
| Ibrutinib M25 | Metabolite | CS-T-93286 | 1839090-60-6 | Enquire |
| Ibrutinib M34 | Metabolite | CS-T-93285 | 1838132-94-7 | Enquire |
| Ibrutinib M35 | Metabolite | CS-O-33508 | Not Available | Enquire |
Impurity
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (R)-N-Desacryloyl N-3-Propionyl Ibrutinib | Impurity | CS-P-01418 | 1288338-96-4 | In Stock |
| (R)-N-Desacryloyl N-Propionyl Ibrutinib | Impurity | CS-T-73365 | 1839099-22-7 | In Stock |
| 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1... | Impurity | CS-O-35292 | ---- | Enquire |
| Ibrutinib (IBR) Diamine Impurity | Impurity | CS-T-93656 | 1987905-93-0 | In Stock |
| Ibrutinib acetyl impurity | Impurity | CS-O-35018 | 1288338-95-3 | In Stock |
| Ibrutinib Amino Piperidine dihydrochloride Impurity | Impurity | CS-ED-00984 | 1701403-10-2 | In Stock |
| Ibrutinib Amino Piperidine Impurity | Impurity | CS-O-32105 | 1022150-12-4 | Enquire |
| Ibrutinib Azo Dimer | Impurity | CS-O-59341 | ---- | Enquire |
| Ibrutinib Diacrylate Analog Impurity | Impurity | CS-SN-00172 | Not Available | In Stock |
| Ibrutinib Diamide Impurity | Impurity | CS-O-37342 | 1917333-91-5 | In Stock |
| Ibrutinib Dimer | Impurity | CS-O-16944 | 2031255-23-7 | In Stock |
| Ibrutinib Di-piperidine impurity | Impurity | CS-O-36026 | Not Available | In Stock |
| Ibrutinib Hydroxy Impurity | Impurity | CS-EO-00584 | 2031255-24-8 | In Stock |
| Ibrutinib Impurity 1 | Impurity | CS-P-01415 | 1022150-11-3 | In Stock |
| Ibrutinib Impurity 106 | Impurity | CS-O-59350 | --- | Enquire |
| Ibrutinib Impurity 107 | Impurity | CS-O-59353 | ---- | Enquire |
| Ibrutinib Impurity 108 | Impurity | CS-O-59355 | ---- | Enquire |
| Ibrutinib Impurity 15 | Impurity | CS-P-08618 | 2031255-26-0 | In Stock |
| Ibrutinib impurity 25 | Impurity | CS-O-51885 | Not Available | Enquire |
| Ibrutinib Impurity 30 | Impurity | CS-O-59315 | 2052279-49-7 | Enquire |
| Ibrutinib Impurity 40 | Impurity | CS-O-59345 | ---- | Enquire |
| Ibrutinib Impurity 41 | Impurity | CS-O-59344 | 2213398-76-4 | Enquire |
| Ibrutinib Impurity 42 | Impurity | CS-EO-02230 | Not Available | Enquire |
| Ibrutinib Impurity 43 | Impurity | CS-O-59779 | ---- | Enquire |
| Ibrutinib Impurity 71 | Impurity | CS-O-57036 | ---- | Enquire |
| Ibrutinib Impurity 8 | Impurity | CS-P-01420 | 330786-24-8 | In Stock |
| Ibrutinib Impurity 83 | Impurity | CS-O-59347 | ---- | Enquire |
| Ibrutinib Impurity 90 | Impurity | CS-O-59043 | 1628179-43-0 | Enquire |
| Ibrutinib Impurity A | Impurity | CS-O-59778 | ---- | Enquire |
| Ibrutinib Impurity D | Impurity | CS-O-42866 | 2052279-48-6 | In Stock |
| Ibrutinib Impurity Dimer | Impurity | CS-O-35023 | 2540665-98-1 | In Stock |
| Ibrutinib malononitrile Impurity | Impurity | CS-O-59342 | ---- | Enquire |
| Ibrutinib Michael addition adduct | Impurity | CS-O-51884 | Not Available | Enquire |
| Ibrutinib N-Carboxyethyl Imine Impurity | Impurity | CS-O-59348 | ---- | Enquire |
| Ibrutinib N-Oxide impurity | Impurity | CS-P-08515 | 2417548-74-2 | In Stock |
| Ibrutinib Piperidine impurity | Impurity | CS-O-51886 | Not Available | Enquire |
| Ibrutinib Piperidine N-desacryl impurity | Impurity | CS-O-51887 | Not Available | Enquire |
| Ibrutinib Propanedinitrile | Impurity | CS-O-59343 | 127635-72-7 | Enquire |
| Ibrutinib Propionyl dimer | Impurity | CS-O-51888 | Not Available | Enquire |
| N6-Acryloyl Ibrutinib | Impurity | CS-T-64851 | 2031255-27-1 | In Stock |
| N-Des Acryloyl Ibrutinib Impurity | Impurity | CS-O-59451 | 1642571-07-0 | Enquire |
| N-Desacryloyl N-(3-Acryloyl-propanoyl) Ibrutinib | Impurity | CS-EO-02889 | 2244619-11-0 | Enquire |
| Rac -Ibrutinib propionaldehyde | Impurity | CS-O-52948 | ---- | Enquire |
| (R)-1-(3-(3-(4-phenoxyphenyl)-4-((triphenyl-l5-phosphaneylid... | Impurity | CS-O-37346 | 2064175-44-4 | Enquire |
| (R)-N-(3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1Hpyrazolo[ | Impurity | CS-O-37344 | 2064175-43-3 | Enquire |
| 4-Hydroxy Ibrutinib | Impurity | CS-EO-04075 | 1288339-18-3 | Enquire |
| Ibrutinib dimer impurity | Impurity | CS-O-34719 | 2417548-83-3 | Enquire |
| Ibrutinib Impurity 47 | Impurity | CS-P-09222 | ---- | Enquire |
| Ibrutinib Impurity 6 | Impurity | CS-EO-00984 | Not Available | Enquire |
| Ibrutinib Impurity 7 | Impurity | CS-EO-00985 | 2213398-75-3 | Enquire |
| Ibrutinib Impurity 9 | Impurity | CS-O-33906 | 2171352-31-9 | Enquire |
| Ibrutinib N1-Oxide | Impurity | CS-EO-01160 | 2437254-47-0 | Enquire |
| N1-(2-Carboxyethyl) Ibrutinib | Impurity | CS-EO-00336 | Not Available | Enquire |
| N-Desacryloyl N-3-hydroxypropanoyl Ibrutinib | Impurity | CS-O-51883 | Not Available | Enquire |
Intermediate
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| 4-Amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine | Intermediate | CS-M-53963 | 151266-23-8 | In Stock |
| 4-Phenoxybenzoic Acid | Intermediate | CS-T-39240 | 2215-77-2 | In Stock |
Fine Chemicals
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| 1,1-Dicyano-2-methoxy-2-(4-phenoxyphenyl)ethene | Fine Chemicals | CS-O-37654 | 330792-69-3 | Enquire |
| PCI-32765 (Racemate) | Fine Chemicals | CS-ZE-32505 | 936563-87-0 | Enquire |
Nitrosamine
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| N-Nitroso BTK INHIBITOR 1 | Nitrosamine | CS-O-46536 | 2256059-43-3 | In Stock |
| N-Nitroso Ibrutinib Amino piperidine Impurity | Nitrosamine | CS-O-50034 | Not Available | In Stock |
| N-Nitroso Ibrutinib Dimer-II | Nitrosamine | CS-O-58585 | ---- | Enquire |
Analytical Standard
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Ibrutinib Acetate D5-AR Grade | Analytical Standard | CS-O-03390-10MG | 1553977-17-5(Freebase) | Enquire |
| Ibrutinib Acetate D5-AR Grade-10 ppm/ACN | Analytical Standard | CS-O-03390-1ML | 1553977-17-5(Freebase) | Enquire |
| Ibrutinib D5-AR Grade | Analytical Standard | CS-O-13635-10MG | 1553977-17-5 | Enquire |
| Ibrutinib D5-AR Grade-10 ppm/ACN | Analytical Standard | CS-O-13635-1ML | 1553977-17-5 | Enquire |
Building Blocks
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Ibrutinib-biotin | Building Blocks | CS-ZB-30717 | 1599432-18-4 | Enquire |
Chiral
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (S)-Ibrutinib | Chiral | CS-O-13638 | 936563-97-2 | In Stock |