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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Indoline, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Indoline impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Indoline-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Indoline Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(5,5’-Bis(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl... Stable Isotopes CS-T-99367 Not Available Enquire
1-(2,6-Dichloro-4-hydroxyphenyl)indoline-2,3-dione-d4 Stable Isotopes CS-T-100480 Not Available Enquire
2-(1-(4-Bromophenyl)propan-2-yl)isoindoline-1,3-dione-d6 Stable Isotopes CS-T-96836 Not Available Enquire
2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)-4-nitroisoindoline-1,3... Stable Isotopes CS-T-102531 6383-80-8(Unlabelled) Enquire
2-(3-((2-(Tritylthio)ethyl)amino)propyl)isoindoline-1,3-dion... Stable Isotopes CS-T-101991 Not Available Enquire
2-(4-((5,6-Dimethoxyquinolin-8-yl)amino)pentyl)isoindoline-1... Stable Isotopes CS-T-98656 Not Available Enquire
N-(4-Chloro-3-sulfamoylbenzoyl)-2-methylindoline-d3 Stable Isotopes CS-T-98667 Not Available Enquire
Vindoline-d3 Stable Isotopes CS-T-97098 Not Available Enquire


API

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(2'R,3S,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluorophenyl)-N-((S... API CS-ED-41461 908027-40-7 Enquire
Vindoline API CS-T-62733 2182-14-1 In Stock


Metabolite

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
1-amino-2-methylindoline Hydrochloride Metabolite CS-O-07863 102789-79-7 In Stock


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(2R,3R)-3-((1H-1,2,4-triazol-1-yl)methyl)-6-fluoro-3-hydroxy... Impurity CS-O-33177 2252350-11-9 Enquire
(R)-1-methylindoline-3,5,6-triol Impurity CS-O-46046 62322-82-1 Enquire
(R)-2-(2-hydroxy-3-((2-hydroxyethyl)(phenyl)amino)propyl)iso... Impurity CS-O-44138 1175817-46-5 Enquire
(S)-2-((2-oxo-3-phenyloxazolidin-5-yl)methyl)isoindoline-1,3... Impurity CS-O-44133 2137914-93-1 Enquire
(S)-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)... Impurity CS-O-40103 2077897-93-7 Enquire
(S)-2-(2-hydroxy-3-(phenylamino)propyl)isoindoline-1,3-dione Impurity CS-O-44132 Not Available Enquire
(Z)-3-(1-hydroxypropylidene)-2-oxo-1-propionylindoline-6-car... Impurity CS-O-44850 Not Available Enquire
(Z)-methyl 3- (1-methoxypropylidene)-2-oxo-1-propionylindoli... Impurity CS-O-44851 Not Available Enquire
2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methyl sulfonyl)ethyl)-4-... Impurity CS-O-34486 253168-82-0 Enquire
2,2'-Dihydroxy-3,3'-dioxo-[2,2'-biindoline]-5,5'-disulfonic ... Impurity CS-O-59163 786615-03-0 Enquire
2-methyl-4-(4-(2-(4-((2-methyl-1,3-dioxoisoindolin-5-yl)oxy)... Impurity CS-O-44624 63227-27-0 Enquire
4,4'-((propane-2,2-diylbis(4,1-phenylene))bis(oxy))bis(2-met... Impurity CS-O-44623 54395-51-6 Enquire
4-amino-2'-(1-(3-ethoxy-4-methoxyphenyl)-2-(methyl sulfonyl)... Impurity CS-O-34487 Not Available Enquire
4-amino-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methyl sulfonyl)e... Impurity CS-O-34485 253168-83-1 In Stock
5-(4-(2-(4-hydroxyphenyl)propan-2-yl)phenoxy)-2-methylisoind... Impurity CS-O-44625 61864-47-9 Enquire
Bromfenac Impurity (7-(4-bromobenzoyl)indoline-2,3-dione) Impurity CS-P-07314 241825-88-7 In Stock
Methyl (Z)-3-((4-(2-((4-((((Z)-6-(methoxycarbonyl)-2-oxoindo... Impurity CS-O-59167 ---- Enquire
methyl (Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carb... Impurity CS-O-36824 1438271-13-6 Enquire
Methyl 2-oxo-1-propionylindoline-6-carboxylate Impurity CS-O-44848 Not Available Enquire


Intermediate

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(S)-(-)-Indoline-2-Carboxylic Acid Intermediate CS-BW-00064 79815-20-6 In Stock
(S)-5-methyl-2-(piperidin-3-yl)isoindoline-1,3-dione Intermediate CS-O-52619 Not Available Enquire
2-(2-(butyl-1,1-d2)benzofuran-5-yl-3,4,6,7-d4)isoindoline-1,... Intermediate CS-O-57763 --- In Stock
2-(2-butylbenzofuran-5-yl)isoindoline-1,3-dione Intermediate CS-O-57767 ---- In Stock
7-Methylindoline-2,3-dione Intermediate CS-M-19452 1127-59-9 In Stock


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(R)-2-((2-Oxooxazolidin-5-yl)methyl)isoindoline-1,3-dione Fine Chemicals CS-O-33329 352524-58-4 Enquire
2-(2,3-dichloro-6-nitrobenzyl)isoindoline-1,3-dione Fine Chemicals CS-O-37664 2116483-30-6 Enquire
2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione Fine Chemicals CS-ED-42151 835616-60-9 Enquire
2-(4-Bromobutyl)Isoindoline-1,3-Dione Fine Chemicals CS-DE-01505 5394-18-3 In Stock
2-(Bromomethyl)isoindoline-1,3-dione Fine Chemicals CS-O-55119 5332-26-3 In Stock
2-Methylindoline Fine Chemicals CS-MM-47397 6872-06-6 In Stock
5,6-Dihydroxyindoline-2-carboxylic acid Fine Chemicals CS-DV-00936 18791-20-3 Enquire
5-bromoindoline-3-carboxylic acid Fine Chemicals CS-O-38182 1368633-81-1 Enquire
5'-bromospiro[cyclopropane-1,2'-indoline]-3'-carboxylic acid Fine Chemicals CS-O-38183 2167145-71-1 Enquire
5-hydroxy-2-methylindoline-3-carboxylic acid Fine Chemicals CS-O-38180 1896809-73-6 Enquire
5-hydroxyindoline-3-carboxylic acid Fine Chemicals CS-O-38178 1892954-72-1 Enquire
6-bromoindoline-3-carboxylic acid Fine Chemicals CS-O-38181 1368752-95-7 Enquire
dimethyl 1-methyl-2-oxoindoline-3,6-dicarboxylate Fine Chemicals CS-O-40813 Not Available Enquire
Indoline-1-carbonyl chloride Fine Chemicals CS-ZJ-10320 117086-91-6 Enquire
Isoindoline Fine Chemicals CS-O-49998 496-12-8 Enquire
isoindoline-1-carboxamide Fine Chemicals CS-O-34991 1095715-76-6 Enquire


Nitrosamine

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(R)-2-methyl-1-nitrosoindoline Nitrosamine CS-O-40546 77083-49-9 Enquire
(R)-5-methyl-2-(1-nitrosopiperidin-3-yl)isoindoline-1,3-dion... Nitrosamine CS-O-52664 Not Available Enquire
3-methyl-1-nitrosoindoline Nitrosamine CS-O-47136 Not Available Enquire
N-nitroso Indoline Nitrosamine CS-T-94204 7633-57-0 In Stock


Stable Isotope Reagent

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Indoline-2,3-dione-4,5,6,7-d4 Stable Isotope Reagent CS-O-48920 492998-53-5 Enquire


Carbohydrates

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2-((4aR,6S,7S,8R,8aS)-hexahydro-8-hydroxy-2-phenyl-6-(phenyl... Carbohydrates CS-O-55501 127061-09-0 Enquire