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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Ivabradine, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Ivabradine impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Ivabradine-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Ivabradine Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Ivabradine-d3 Stable Isotopes CS-O-03179 1217977-70-2 In Stock
Ivabradine-d3 N-oxide Stable Isotopes CS-T-97375 Not Available Enquire
Ivabradine-d6 Hydrochloride Stable Isotopes CS-O-06695 148870-59-1(Unlabeled) In Stock
N-Desmethyl Ivabradine-d6 Hydrochloride Stable Isotopes CS-O-06693 1346600-74-5 In Stock
Rac-Ivabradine D6 Stable Isotopes CS-EO-02954 148870-59-1 (Unlabeled free base) Enquire
Dehydro Ivabradine-d3 Stable Isotopes CS-T-73566 1795787-01-7 Enquire
Ivabradine-D3 Hydrochloride Stable Isotopes CS-O-15064 1217809-61-4 Enquire
Ivabradine-d4 Hydrochloride Stable Isotopes CS-T-93261 Not Available Enquire
N-Desmethyl Ivabradine D4 Hydrochloride Stable Isotopes CS-T-93262 Not Available Enquire
N-Desmethyl-Ivabradine D6 Stable Isotopes CS-O-14399 1346746-80-2 Enquire


API

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Ivabradine API CS-O-01679 155974-00-8 In Stock
Ivabradine HCl racemic mixture API CS-O-41636 Not Available Enquire
Ivabradine Hydrochloride API CS-O-11672 148849-67-6 In Stock
Rac-Ivabradine API CS-O-50232 148870-59-1 Enquire


Metabolite

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2-hydroxy Ivabradine impurity Metabolite CS-O-52615 Not Available Enquire
2-hydroxy R-Ivabradine impurity Metabolite CS-O-45746 Not Available Enquire
Ivabradine N-Oxide Impurity Metabolite CS-O-10356 2511244-97-4 In Stock
N-Desmethyl Ivabradine Metabolite CS-O-06005 215935-23-2 Enquire


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
1-Hydroxy Ivabradine Impurity CS-K-00308 2511244-96-3 Enquire
2-Oxo-Ivabradine Impurity CS-O-52416 1616710-52-1 Enquire
3-(3-iodopropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d... Impurity CS-O-37262 1192174-73-4 Enquire
3,4-Dimethoxy-N-methylbicyclo[4.2.0]octa-1,3,5-triene-7-meth... Impurity CS-O-48147 148870-56-8 Enquire
3-Hydroxy Ivabradine Hydrochloride Impurity CS-EO-03632 304464-98-0 (Freebase) Enquire
7,8-Dimethoxy-3-propyl-1,3,4,5-tetrahydro-2H-3-benzazepin-2-... Impurity CS-O-49110 2512208-76-1 Enquire
7-Demethyl Ivabradine (HCl salt) Impurity CS-EO-03630 304462-60-0 (Freebase) Enquire
8-Demethyl Ivabradine Impurity CS-T-16432 304464-97-9 Enquire
8-Demethyl Ivabradine (HCl salt) Impurity CS-EO-03631 304464-97-9 (Freebase) Enquire
Dehydro Ivabradine Impurity CS-T-51739 1086026-31-4 In Stock
Demethyl Ivabradine HCl Impurity CS-O-35711 304465-03-0 (free base) Enquire
Ivabradine 12 Isomer Impurity Impurity CS-EO-02858 Not Available Enquire
Ivabradine 3-chloro N-methylpropanamine-Benzocyclobutane imp... Impurity CS-O-45771 1031767-71-1 In Stock
Ivabradine Acetyl analogue Impurity CS-EO-00280 2512206-14-1 Enquire
Ivabradine Amine Hydrochloride Impurity CS-O-32291 866783-13-3 In Stock
Ivabradine Hydroxy Impurity Impurity CS-P-01059 1235547-07-5 Enquire
Ivabradine Impurity 1 Impurity CS-P-01060 1462470-54-7 Enquire
Ivabradine Impurity 11 Impurity CS-P-01070 1132667-04-9 Enquire
Ivabradine Impurity 2 Impurity CS-P-01061 73954-34-4 In Stock
Ivabradine Impurity 20 Impurity CS-O-59358 ---- Enquire
Ivabradine Impurity 24 Impurity CS-O-59339 ---- Enquire
Ivabradine Impurity 27 HCl Impurity CS-O-56491 2768438-46-4 (Freebase) Enquire
Ivabradine Impurity 28 HCl Impurity CS-O-56493 ---- Enquire
Ivabradine Impurity 3 Impurity CS-P-01062 ---- Enquire
Ivabradine Impurity 32 HCl Impurity CS-O-56495 ---- Enquire
Ivabradine Impurity 33 HCl Impurity CS-O-56458 96254-66-9 (free base) Enquire
Ivabradine Impurity 34 HCl Impurity CS-O-56459 2373259-08-4 (free base) Enquire
Ivabradine Impurity 4 Impurity CS-P-01063 ---- Enquire
Ivabradine Impurity 44 Impurity CS-O-58502 1616710-51-0 Enquire
Ivabradine Impurity 6 Impurity CS-P-01065 869856-07-5 Enquire
Ivabradine Impurity 62 Impurity CS-O-59369 2458312-06-4 Enquire
Ivabradine Impurity 8 Impurity CS-P-01067 85175-65-1 Enquire
Ivabradine Open Ring Hydrochloride Impurity CS-O-48708 1462470-54-7 (Freebase) Enquire
N-desmethyl Ivabradine HCl Impurity CS-T-16433 1246638-08-3 In Stock
rac Acetyl Ivabradine impurity Impurity CS-O-59338 --- Enquire
rac Ivabradine Impurity 27 Impurity CS-O-59373 ---- Enquire
Rac-Ivabradine Hydrochloride Impurity CS-O-52418 1796933-38-4 Enquire
R-Ivabradine Impurity CS-O-54300 167072-91-5 Enquire
R-Ivabradine HCl Impurity CS-O-16957 148849-68-7 Enquire
(7R)-3,4-Dimethoxy-N-methyl-bicyclo[4.2.0]octa-1,3,5-triene-... Impurity CS-T-89802 1204612-29-2 Enquire
(R)-Ivabradine Oxalicacid Impurity CS-O-51501 1232191-91-1 Enquire
(S)-1-(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-m... Impurity CS-EO-02011 866783-12-2 Enquire
(S)-3-(3-((3-chloro-2-(3,4-dimethoxyphenyl)propyl)(methyl)am... Impurity CS-O-35681 Not Available Enquire
(S)-3-(3-((3-chloro-2-(3,4-dimethoxyphenyl)propyl)(methyl)am... Impurity CS-O-35712 Not Available Enquire
2-(3,4-dimethoxyphenyl)-N-(2-oxoethyl)acetamide Impurity CS-ED-00889 Not Available Enquire
3-(3,4-Dimethoxy-phenyl)-propylamine Impurity CS-M-06965 14773-42-3 Enquire
3-(3-bromo-4,5-dimethoxyphenyl)propanenitrile Impurity CS-O-38211 2229445-09-2 Enquire
3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1,3,4,5-tetrahydro-... Impurity CS-EO-00225 2731089-65-7 Enquire
5-Hydroxy Ivabradine Impurity CS-O-35969 2253977-80-7 Enquire
7, 8-dimethoxy-1, 3, 4, 5-tetrahydrobenzo[d]azepin-2-one Impurity CS-O-31738 20925-64-8 Enquire
7,8-dimethoxy-3-(3-(methylamino)propyl)-2,3,4,5-tetrahydro-1... Impurity CS-O-41132 Not Available Enquire
7,8-Dimethoxy-3-(3-iodopropyl)-1,3-dihydro-2H-3-benzazepin-2... Impurity CS-O-32417 148870-57-9 Enquire
Dehydro Ivabradine HCl salt Impurity CS-O-34415 1086026-38-1 Enquire
Dehydro Ivabradine Oxalate Impurity CS-P-01058 1346558-08-4 Enquire
IVABRADINE - N OXIDE impurity Impurity CS-O-51695 Not Available Enquire
Ivabradine Dimer Impurity CS-O-16956 Not Available Enquire
Ivabradine Impurity 10 Impurity CS-P-01069 Not Available Enquire
Ivabradine Impurity 12 Impurity CS-P-01071 ---- Enquire
Ivabradine Impurity 13 Impurity CS-P-01072 Not Available Enquire
Ivabradine Impurity 14 Impurity CS-P-01073 Not Available Enquire
Ivabradine Impurity 15 Impurity CS-P-01074 1616710-50-9 Enquire
Ivabradine Impurity 16 Impurity CS-P-01075 ---- Enquire
Ivabradine Impurity 25 Impurity CS-EO-01002 1797099-93-4 Enquire
Ivabradine Impurity 26 Impurity CS-EO-01001 Not Available Enquire
Ivabradine Impurity 37 Impurity CS-EO-01061 Not Available Enquire
Ivabradine Impurity 41 Impurity CS-P-08960 Not Available Enquire
Ivabradine Impurity 5 Impurity CS-P-01064 Not Available Enquire
Ivabradine Impurity 6 HCl Impurity CS-P-08786 Not Available Enquire
Ivabradine Impurity 9 Impurity CS-P-01068 Not Available Enquire
Ivabradine Impurity B Impurity CS-O-35441 Not Available Enquire
Ivabradine Keto impurity Impurity CS-O-38818 Not Available Enquire
Ivabradine oxalate Impurity CS-O-36919 1086026-42-7 Enquire
Ivabradine Oxalate Impurity A Impurity CS-O-36840 Not Available Enquire
Ivabradine Oxalate Impurity B Impurity CS-O-36920 Not Available Enquire
Ivabradine Oxalate Impurity D Impurity CS-O-36841 Not Available Enquire
Ivabradine Oxalate Impurity F Impurity CS-O-36842 Not Available Enquire
Ivabradine Oxalate R-Isomer Impurity CS-O-36843 Not Available Enquire


Intermediate

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
3-(3-bromopropyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepi... Intermediate CS-O-44651 1192174-72-3 Enquire
7, 8-dimethoxy-3-(3-chloropropyl)-1, 3-dihydro-2H-3-benzazep... Intermediate CS-O-31740 85175-59-3 In Stock


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
3-(3-bromopropyl)-7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-... Fine Chemicals CS-O-34201 1428869-91-3 In Stock
3-(2-bromo-3,4-dimethoxyphenyl)propanenitrile Fine Chemicals CS-O-38669 2228529-29-9 Enquire


Nitrosamine

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Ivabradine Impurity 40 Nitrosamine CS-EO-03200 Not Available Enquire
Ivabradine Nitroso Impurity 1 Nitrosamine CS-EO-03201 Not Available Enquire
Ivabradine N-nitroso Impurity Nitrosamine CS-O-46597 Not Available In Stock
N-Nitroso N-Desmethyl Ivabradine Nitrosamine CS-EO-01261 3017270-16-2 Enquire