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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for L-proline, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our L-proline impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our L-proline-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

L-proline Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(4S)-4-(Phenylthio)-L-proline-d5 Hydrochloride Stable Isotopes CS-T-94385 105107-84-4(Unlabelled) Enquire
Cis-4-Hydroxy-L-proline-2,5,5 D3 Stable Isotopes CS-O-15051 618-27-9 (Unlabeled) Enquire
Des(4-cyclohexyl-L-proline) Fosinopril Acetic Acid-d7 Stable Isotopes CS-T-97635 Not Available Enquire
DL-Proline-2,5,5-d3 Stable Isotopes CS-T-94101 784086-28-8 Enquire
L-Alanyl-L-proline-d3 t-Butyl Ester Stable Isotopes CS-T-100917 Not Available Enquire
L-Proline-d3-N-Fmoc Stable Isotopes CS-T-99862 Not Available Enquire
N-Nitroso L-Proline-d3 Stable Isotopes CS-O-11223 2140267-23-6 In Stock
N-Nitroso-DL-Proline-d3 Stable Isotopes CS-O-10299 65807-08-1 In Stock
N-Nitroso-L-proline D7 Stable Isotopes CS-O-53737 7519-36-0 (Unlabeled) Enquire
rac-Des(4-cyclohexyl-L-proline) Fosinopril Acetic Acid-d7 Stable Isotopes CS-T-101091 Not Available Enquire
trans-4-Hydroxy-L-proline-d4 (Major) Stable Isotopes CS-T-102915 2734920-51-3 Enquire
trans-4-Hydroxy-L-proline-d6 Stable Isotopes CS-T-100179 Not Available Enquire
(4R)-1-Methyl-4-propyl-L-proline-d3 Methyl Ester Stable Isotopes CS-T-81532 1246815-09-7 Enquire
(trans)-4-Propyl-1-methyl-L-proline-d3 Stable Isotopes CS-T-85221 1246816-92-1 Enquire
[1,2-13C2,15N]-L-Proline Stable Isotopes CS-EK-01682 219491-68-6 Enquire
[2-13C]-L-Proline Stable Isotopes CS-EK-01753 219491-78-8 Enquire
[2-13C]-L-Proline amide Stable Isotopes CS-EK-00707 7531-52-4 unlabeled Enquire
1-Nitroso-DL-proline 13C5,15N Stable Isotopes CS-EK-01248 2571-28-0 unlabeled Enquire
5-Oxo-DL-proline D5 Stable Isotopes CS-T-60039 352431-30-2 Enquire


API

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
L-Proline rubidium salt API CS-O-51900 151600-44-1 Enquire


Metabolite

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
N-Boc-4-oxo-L-proline methyl ester Metabolite CS-M-42334 102195-80-2 Enquire


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
((S)-4-(2-chlorophenyl)-1-ethoxy-1-oxobutan-2-yl)-L-alanyl-L... Impurity CS-O-58632 85918-76-9 Enquire
((S)-4-(4-chlorophenyl)-1-ethoxy-1-oxobutan-2-yl)-L-alanyl-L... Impurity CS-O-58633 ---- Enquire
(4R)-4-[2-(1,1-Dimethylethoxy)-2-oxoethoxy]-L-proline Impurity CS-O-58110 2173568-86-8 Enquire
(4S)-4-(Phenylthio)-L-proline Hydrochloride Impurity CS-T-60509 105107-84-4 In Stock
1-(N-(S-1-Carboxy-3-cyclohexylpropyl)-L-Alanyl) L-Proline-et... Impurity CS-O-56402 ---- Enquire
DL-Proline Impurity CS-T-40571 609-36-9 In Stock
Ipragliflozin L-Proline Impurity CS-O-13214 951382-34-6 In Stock
L-Proline β-naphthylamide hydrochloride Impurity CS-BX-02706 97216-16-5 Enquire
(4R)-4-Benzyloxy-L-Proline methyl ester Impurity CS-AC-03840 113490-76-9 Enquire
(4S)-4-Cyclohexyl-1-[[hydroxy(4-phenylbutyl)phosphinyl]acety... Impurity CS-T-14174 474382-58-6 Enquire
(R)-1-[N-[1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-pro... Impurity CS-T-76443 139492-22-1 Enquire
1-(1-Oxopropyl)-(4S)-4-cyclohexyl-L-proline Impurity CS-T-59842 1421283-57-9 Enquire
1-(3,3-Dimethyl-1,2-dioxopentyl)-L-proline 3-(3-pyridinyl)pr... Impurity CS-T-53532 186452-09-5 Enquire
4-Cyclobutyl-L-Proline Methyl Ester Hydrochloride Impurity CS-BW-00032 Not Available Enquire
4-Cyclopropyl-L-Proline Methyl Ester Hydrochloride Impurity CS-BW-00033 1296797-07-3 Enquire
7-Methoxycoumarin-4-acetyl-L-proline Impurity CS-T-32339 359436-90-1 Enquire
Boc-(R)-alpha-benzyl-proline Impurity CS-AC-03977 706806-60-2 Enquire
Boc-(S)-alpha-benzyl-proline Impurity CS-AC-03852 706806-61-3 Enquire
Boc-3,4-dehydro-L-proline Impurity CS-T-67633 51154-06-4 Enquire
Boc-cis-3-hydroxy-L-proline Impurity CS-T-68550 186132-96-7 Enquire
Cis-4-Mercapto-L-proline hydrochloride Impurity CS-AC-07998 78854-27-0 Enquire
L-Alanyl-L-proline tert-Butyl Ester Impurity CS-T-01513 29375-30-2 Enquire
L-Proline, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ... Impurity CS-EM-02840 168263-82-9 Enquire
N-(tert-Butoxycarbonyl)-(3S)-hydroxy-L-proline methyl ester Impurity CS-N-00466 184046-78-4 Enquire
N-Methacryloyl-L-proline Impurity CS-T-32097 51161-88-7 Enquire
O-[(2S)-3,3-Dimethyl-N-benzyl-proline Methyl Ester] S-Methyl... Impurity CS-T-53439 1219237-13-4 Enquire
trans 4-Hydroxy-L-proline -β-Naphthylamide Impurity CS-T-28453 3326-64-5 Enquire
trans-1-benzoyl-4-phenyl-l-proline Impurity CS-O-31683 120851-71-0 Enquire
trans-N-tert-Butyloxycarbonyl-4-tosyloxy-L-proline Methyl Es... Impurity CS-T-50143 88043-21-4 Enquire


Intermediate

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
L-Proline Benzyl Ester Hydrochloride Intermediate CS-T-85098 16652-71-4 In Stock
L-Proline t-butyl ester Intermediate CS-M-47114 2812-46-6 In Stock
L-Prolylglycyl-L-proline Intermediate CS-O-59100 7561-51-5 Enquire
N-Boc-4-Oxo-L-proline Intermediate CS-M-57250 84348-37-8 In Stock
trans-4-Hydroxy-L-proline Intermediate CS-T-28448 51-35-4 In Stock


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Glycyl-L-proline 7-amido-4-methylcoumarin hydrobromide Fine Chemicals CS-CE-00752 115035-46-6 In Stock
L-Proline Fine Chemicals CS-T-40567 147-85-3 In Stock
L-Proline tetrazole Fine Chemicals CS-P-09174 33878-70-5 Enquire
L-Alanyl-L-proline Fine Chemicals CS-T-01512 13485-59-1 Enquire


Building Blocks

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
1-L-Prolyl-L-proline Hydrochloride Building Blocks CS-ED-42209 76932-06-4 Enquire
boc-trans-Hydroxy-L-proline Building Blocks CS-T-28484 13726-69-7 In Stock
L-Lysyl-L-proline Building Blocks CS-T-57344 52766-27-5 In Stock
L-Proline, methyl ester Building Blocks CS-O-47363 2577-48-2 Enquire
N-Acetyl-L-proline Building Blocks CS-O-30988 68-95-1 In Stock
N-Phenacetyl-L-proline Building Blocks CS-O-56958 2752-38-7 Enquire
((Benzyloxy)carbonyl)-D-alanyl-L-proline Building Blocks CS-O-52379 22209-78-5 Enquire
((Benzyloxy)carbonyl)-D-prolyl-L-proline Building Blocks CS-O-52375 1221446-62-3 Enquire
(3-(((Benzyloxy)carbonyl)amino)propanoyl)-L-proline Building Blocks CS-O-52376 61058-47-7 Enquire
(4R)-4-Hydroxy-1-methyl-L-proline Building Blocks CS-T-78532 4252-82-8 Enquire
(4R)-4-Propyl-L-proline Building Blocks CS-O-16130 31101-27-6 Enquire
(R)-1-(3-Bromo-2-methyl-1-oxopropyl)-L-proline Building Blocks CS-T-49801 80629-36-3 Enquire
(trans)-4-Propyl-L-proline Methyl Ester Building Blocks CS-T-40809 1356354-47-6 Enquire
1-(1-Oxohexadecyl)-L-proline sodium salt Building Blocks CS-M-54946 58725-33-0 Enquire
1-[(2R)-3-Hydroxy-2-methyl-1-oxopropyl]-L-proline Building Blocks CS-T-56218 613256-52-3 Enquire
1-[(2S)-3-(Acetylthio)-2-methylpropionyl]-L-proline Building Blocks CS-O-32312 64838-55-7 Enquire
1-[1-Deoxy-2,3:4,5-bis-O-(1-methylethylidene)-ß-D-fructopyra... Building Blocks CS-T-73403 173966-36-4 Enquire
1-[N2,N6-Bis[(phenylmethoxy)carbonyl]-L-lysyl]-L-proline Phe... Building Blocks CS-T-67730 145435-28-5 Enquire
1-ethyl-L-proline Building Blocks CS-TB-45312 98435-76-8 Enquire
3,4-Dehydro-L-proline Hydrochloride Building Blocks CS-T-73383 201469-31-0 Enquire
3-Allohydroxy-L-proline;cis-3-Hydroxy-L-proline; cis-3-Hydro... Building Blocks CS-DV-02096 567-35-1 Enquire
Biocytin-L-proline Building Blocks CS-T-49113 1356931-03-7 Enquire
Biocytin-N-(t-boc)-L-proline Building Blocks CS-T-49112 1356383-21-5 Enquire
Boc-L-proline methyl ester Building Blocks CS-DB-00032 59936-29-7 Enquire
cis-4-Hydroxy-L-proline Building Blocks CS-T-28447 618-27-9 Enquire
cis-4-Hydroxy-L-proline Methyl Ester Hydrochloride Building Blocks CS-T-78918 40126-30-5 Enquire
N-(tert-Butoxycarbonyl)-L-proline Building Blocks CS-T-49551 15761-39-4 Enquire
N6-Trifluoroacetyl-L-lysyl-L-proline Building Blocks CS-T-88014 103300-89-6 Enquire
N-acetyl-4-oxo-L-proline Building Blocks CS-O-13059 76868-78-5 Enquire
N-benzyloxycarbonyl-L-alanyl-L-proline Building Blocks CS-ED-42210 21027-01-0 Enquire
N-Boc-alpha-methyl-l-proline Building Blocks CS-DL-00112 103336-06-7 Enquire
N-Boc-trans-4-amino-L-proline methyl ester Building Blocks CS-AC-04713 121148-00-3 Enquire
N-Carbobenzoxy-l-proline tert-butyl ester Building Blocks CS-T-70241 16881-39-3 Enquire
N-Cbz-cis-4-hydroxy-l-proline methyl ester Building Blocks CS-T-70357 57653-35-7 Enquire
N-CBZ-Glycyl-L-proline 7-Amido-4-methylcoumarin Building Blocks CS-T-68993 68542-93-8 Enquire
trans-4-Hydroxy-1-L-phenylalanyl-L-proline Building Blocks CS-T-78088 90965-82-5 Enquire
trans-4-Methyl-L-proline Hydrochloride Building Blocks CS-T-34243 365280-18-8 Enquire


Nitrosamine

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
1-nitroso-DL-Proline Nitrosamine CS-O-49119 2571-28-0 In Stock
N-Nitroso-L-proline Nitrosamine CS-T-37289 7519-36-0 In Stock
Vildagliptin N-Nitroso-L-Proline Methyl Ester Nitrosamine CS-EO-01927 35909-01-4 In Stock