Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for L-proline, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our L-proline impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our L-proline-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Our L-proline-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
L-proline Related Compounds
Stable Isotopes
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| "[1,2-13C2,15N]-L-Proline" | Stable Isotopes | CS-EK-01682 | 219491-68-6 | Enquire |
| "[13C5,15N]-1-Nitroso-DL-proline" | Stable Isotopes | CS-EK-01248 | 2571-28-0 unlabeled | Enquire |
| "L-Proline-13C5, N-Boc" | Stable Isotopes | CS-CH-00153 | 1313730-03-8 | Enquire |
| (4R)-1-Methyl-4-propyl-L-proline-d3 Methyl Ester | Stable Isotopes | CS-T-81532 | 1246815-09-7 | Enquire |
| (4S)-4-(Phenylthio)-L-proline-d5 Hydrochloride | Stable Isotopes | CS-T-94385 | 105107-84-4(Unlabelled) | Enquire |
| (trans)-4-Propyl-1-methyl-L-proline-d3 | Stable Isotopes | CS-T-85221 | 1246816-92-1 | Enquire |
| [2-13C]-L-Proline | Stable Isotopes | CS-EK-01753 | 219491-78-8 | Enquire |
| [2-13C]-L-Proline amide | Stable Isotopes | CS-EK-00707 | 7531-52-4 unlabeled | Enquire |
| 5-Oxo-DL-proline D5 | Stable Isotopes | CS-T-60039 | 352431-30-2 | Enquire |
| Cis-4-Hydroxy-L-proline-2,5,5 D3 | Stable Isotopes | CS-O-15051 | 618-27-9 (Unlabeled) | Enquire |
| cis-4-Hydroxy-L-proline-2,5,5-d3 | Stable Isotopes | CS-C-01331 | 618-27-9 (Unlabelled) | Enquire |
| Des(4-cyclohexyl-L-proline) Fosinopril Acetic Acid-d7 | Stable Isotopes | CS-T-97635 | Not Available | Enquire |
| DL-Proline D7 Hydrochloride | Stable Isotopes | CS-T-60778 | 65807-21-8 (Freebase) | Enquire |
| L-Alanyl-L-proline-d3 t-Butyl Ester | Stable Isotopes | CS-T-100917 | Not Available | Enquire |
| L-Proline-13C5,15N | Stable Isotopes | CS-T-95778 | Not Available | Enquire |
| L-Proline-15N | Stable Isotopes | CS-CH-00155 | 59681-31-1 | Enquire |
| L-Proline-15N, N-Fmoc | Stable Isotopes | CS-CH-00156 | 204523-24-0 | Enquire |
| L-Proline-d3-N-Fmoc | Stable Isotopes | CS-T-99862 | Not Available | Enquire |
| N-Nitroso L-Proline-d3 | Stable Isotopes | CS-O-11223 | 2140267-23-6 | In Stock |
| N-Nitroso-DL-Proline-d3 | Stable Isotopes | CS-O-10299 | 65807-08-1 | In Stock |
| N-Nitroso-L-proline D7 | Stable Isotopes | CS-O-53737 | 7519-36-0 (Unlabeled) | Enquire |
| trans-4-Hydroxy-L-proline-d3 | Stable Isotopes | CS-T-78819 | 1356016-86-8 | Enquire |
| trans-4-Hydroxy-L-proline-d6 | Stable Isotopes | CS-T-100179 | Not Available | Enquire |
API Standards
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| 1-[1-Deoxy-2,3:4,5-bis-O-(1-methylethylidene)-ß-D-fructopyra... | API Standards | CS-T-73403 | 173966-36-4 | Enquire |
| L-Proline rubidium salt | API Standards | CS-O-51900 | 151600-44-1 | Enquire |
Metabolites
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| N-Boc-4-oxo-L-proline methyl ester | Metabolites | CS-M-42334 | 102195-80-2 | Enquire |
Impurities
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| "Boc-3,4-dehydro-L-proline" | Impurities | CS-T-67633 | 51154-06-4 | Enquire |
| "O-[(2S)-3,3-Dimethyl-N-benzyl-proline Methyl Ester] S-Methy... | Impurities | CS-T-53439 | 1219237-13-4 | Enquire |
| ((S)-4-(4-chlorophenyl)-1-ethoxy-1-oxobutan-2-yl)-L-alanyl-L... | Impurities | CS-O-58633 | Not Available | Enquire |
| (4R)-4-Benzyloxy-L-Proline methyl ester | Impurities | CS-AC-03840 | 113490-76-9 | Enquire |
| (4S)-4-(Phenylthio)-L-proline Hydrochloride | Impurities | CS-T-60509 | 105107-84-4 | In Stock |
| (4S)-4-Cyclohexyl-1-[[hydroxy(4-phenylbutyl)phosphinyl]acety... | Impurities | CS-T-14174 | 474382-58-6 | Enquire |
| (R)-1-[N-[1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-pro... | Impurities | CS-T-76443 | 139492-22-1 | Enquire |
| 1-(1-Oxopropyl)-(4S)-4-cyclohexyl-L-proline | Impurities | CS-T-59842 | 1421283-57-9 | Enquire |
| 1-(3,3-Dimethyl-1,2-dioxopentyl)-L-proline 3-(3-pyridinyl)pr... | Impurities | CS-T-53532 | 186452-09-5 | Enquire |
| 1-(N-(S-1-Carboxy-3-cyclohexylpropyl)-L-Alanyl) L-Proline-et... | Impurities | CS-O-56402 | Not Available | Enquire |
| 4-Cyclobutyl-L-Proline Methyl Ester Hydrochloride | Impurities | CS-BW-00032 | Not Available | Enquire |
| 4-Cyclopropyl-L-Proline Methyl Ester Hydrochloride | Impurities | CS-BW-00033 | 1296797-07-3 | Enquire |
| 7-Methoxycoumarin-4-acetyl-L-proline | Impurities | CS-T-32339 | 359436-90-1 | Enquire |
| Boc-(R)-alpha-benzyl-proline | Impurities | CS-AC-03977 | 706806-60-2 | Enquire |
| Boc-(S)-alpha-benzyl-proline | Impurities | CS-AC-03852 | 706806-61-3 | Enquire |
| Boc-cis-3-hydroxy-L-proline | Impurities | CS-T-68550 | 186132-96-7 | Enquire |
| Cis-4-Mercapto-L-proline hydrochloride | Impurities | CS-AC-07998 | 78854-27-0 | Enquire |
| DL-Proline | Impurities | CS-T-40571 | 609-36-9 | In Stock |
| Ipragliflozin L-Proline | Impurities | CS-O-13214 | 951382-34-6 | In Stock |
| L-Alanyl-L-proline tert-Butyl Ester | Impurities | CS-T-01513 | 29375-30-2 | Enquire |
| L-Proline β-naphthylamide hydrochloride | Impurities | CS-BX-02706 | 97216-16-5 | Enquire |
| N-(tert-Butoxycarbonyl)-(3S)-hydroxy-L-proline methyl ester | Impurities | CS-N-00466 | 184046-78-4 | Enquire |
| N-Methacryloyl-L-proline | Impurities | CS-T-32097 | 51161-88-7 | Enquire |
| trans 4-Hydroxy-L-proline -β-Naphthylamide | Impurities | CS-T-28453 | 3326-64-5 | Enquire |
| trans-1-benzoyl-4-phenyl-l-proline | Impurities | CS-O-31683 | 120851-71-0 | Enquire |
| trans-4-Hydroxy-L-proline | Impurities | CS-T-28448 | 51-35-4 | In Stock |
| trans-N-tert-Butyloxycarbonyl-4-tosyloxy-L-proline Methyl Es... | Impurities | CS-T-50143 | 88043-21-4 | Enquire |
Intermediates
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| "(R)-Alpha-allyl-proline, HCl" | Intermediates | CS-T-65828 | 177206-69-8 | Enquire |
| "3,3-Difluoro-L-proline" | Intermediates | CS-T-91279 | 1932019-87-8 | Enquire |
| "L-Proline, 4-methoxy-1-methyl-, trans- hydrochloride" | Intermediates | CS-EM-02623 | 131559-49-4 | Enquire |
| "N-Boc-4,4-difluoro-l-proline methyl ester" | Intermediates | CS-AC-04452 | 203866-17-5 | Enquire |
| (4R)-1-Methyl-4-propyl-L-proline Hydrochloride | Intermediates | CS-T-58348 | 6734-79-8 | Enquire |
| (4R)-1-Methyl-4-propyl-L-proline Methyl Ester | Intermediates | CS-T-58349 | 13380-39-7 | Enquire |
| (4S)-4-(Dimethylamino)-L-proline dihydrochloride | Intermediates | CS-ED-26200 | 1001354-15-9 | Enquire |
| (4S)-4-amino-1-methyl-L-proline | Intermediates | CS-ED-41270 | 1308319-48-3 | Enquire |
| (4S)-4-Cyclohexyl-L-proline Hydrochloride | Intermediates | CS-T-51445 | 90657-55-9 | Enquire |
| (R)-1-Methyl-4-hydroxy-l-proline methyl ester | Intermediates | CS-T-80151 | 13135-69-8 | Enquire |
| (R)-alpha-propynyl-proline-HCl | Intermediates | CS-ED-02527 | 1049733-10-9 | Enquire |
| (S)-alpha-Allyl-proline hydrochloride | Intermediates | CS-ED-05965 | 129704-91-2 | Enquire |
| 4-Hydroxy-1-methyl-proline Hydrochloride | Intermediates | CS-T-78485 | 89771-43-7 | Enquire |
| 5-Oxo-L-prolyl-L-proline | Intermediates | CS-T-84696 | 7652-89-3 | Enquire |
| Boc-(R)-gamma-(4-pyridinylmethyl)-L-proline | Intermediates | CS-ED-17332 | 959581-01-2 | Enquire |
| Boc-DL-proline ethyl ester | Intermediates | CS-AC-02729 | 125347-83-3 | Enquire |
| cis-4-Fluoro-L-Proline | Intermediates | CS-BW-00054 | 2438-57-5 | Enquire |
| Des(4-cyclohexyl-L-proline) Fosinopril Acetic Acid | Intermediates | CS-T-52074 | 128948-00-5 | Enquire |
| L-Proline 7-amido-4-methylcoumarin hydrobromide salt | Intermediates | CS-CE-00698 | 115388-93-7 | Enquire |
| L-Proline Benzyl Ester Hydrochloride | Intermediates | CS-T-85098 | 16652-71-4 | In Stock |
| L-Proline Methyl Ester Hydrochloride | Intermediates | CS-T-40563 | 2133-40-6 | Enquire |
| L-Proline t-butyl ester | Intermediates | CS-M-47114 | 2812-46-6 | In Stock |
| L-Proline, 1-propyl- | Intermediates | CS-ED-33082 | 101253-30-9 | Enquire |
| L-Proline, 4-(benzoylamino)-, methyl ester, hydrochloride (1... | Intermediates | CS-ED-33646 | 943134-38-1 | Enquire |
| L-Prolylglycyl-L-proline | Intermediates | CS-O-59100 | 7561-51-5 | Enquire |
| N-Acetyl-4-hydroxy-L-proline | Intermediates | CS-ED-34306 | 926905-71-7 | Enquire |
| N-Benzyloxycarbonyl-L-lysyl]-L-proline Methyl Ester Trifluor... | Intermediates | CS-T-05822 | 108456-08-2 | Enquire |
| N-Boc-4-methylene-L-proline Methyl Ester | Intermediates | CS-T-49518 | 84348-39-0 | Enquire |
| N-Boc-4-oxo-DL-Proline | Intermediates | CS-AC-03643 | 876317-19-0 | Enquire |
| N-Boc-4-Oxo-L-proline | Intermediates | CS-M-57250 | 84348-37-8 | In Stock |
| N-Boc-4-oxo-l-proline tert-butyl ester | Intermediates | CS-AC-02163 | 166410-05-5 | Enquire |
| N-Boc-cis-4-hydroxy-L-proline (Custom work) | Intermediates | CS-DB-00192 | 87691-27-8 | Enquire |
| N-t-BOC-cis-4-Methyl-L-Proline | Intermediates | CS-BW-00022 | 364750-81-2 | Enquire |
| Phenylalanyl-proline-ß-naphthylamide | Intermediates | CS-T-83873 | 76122-99-1 | Enquire |
| rac-Des(4-cyclohexyl-L-proline) Fosinopril Acetic Acid | Intermediates | CS-T-15659 | 123599-78-0 | Enquire |
| t-Butyl-L-aspartyl-L-proline | Intermediates | CS-T-50008 | 64642-65-5 | Enquire |
| t-Butyl-N-carbobenzyloxy-L-aspartyl-L-proline | Intermediates | CS-T-50014 | 4583-13-5 | Enquire |
| trans-4-Fluoro-L-Proline | Intermediates | CS-BW-00057 | 2507-61-1 | Enquire |
| trans-4-Phenyl-L-proline hydrochloride | Intermediates | CS-ED-33395 | 90657-53-7 | Enquire |
| Z-L-Proline amide | Intermediates | CS-CG-00004 | 34079-31-7 | Enquire |
Fine Chemicals
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (4R)-4-[2-(1,1-Dimethylethoxy)-2-oxoethoxy]-L-proline | Fine Chemicals | CS-O-58110 | 2173568-86-8 | Enquire |
| Glycyl-L-proline 7-amido-4-methylcoumarin hydrobromide | Fine Chemicals | CS-CE-00752 | 115035-46-6 | In Stock |
| L-Alanyl-L-proline | Fine Chemicals | CS-T-01512 | 13485-59-1 | Enquire |
| L-Proline | Fine Chemicals | CS-T-40567 | 147-85-3 | In Stock |
| L-Proline tetrazole | Fine Chemicals | CS-P-09174 | 33878-70-5 | Enquire |
Building Blocks
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (4R)-4-Hydroxy-1-methyl-L-proline | Building Blocks | CS-T-78532 | 4252-82-8 | Enquire |
| (4R)-4-Propyl-L-proline | Building Blocks | CS-O-16130 | 31101-27-6 | Enquire |
| (R)-1-(3-Bromo-2-methyl-1-oxopropyl)-L-proline | Building Blocks | CS-T-49801 | 80629-36-3 | Enquire |
| (trans)-4-Propyl-L-proline Methyl Ester | Building Blocks | CS-T-40809 | 1356354-47-6 | Enquire |
| 1-(1-Oxohexadecyl)-L-proline sodium salt | Building Blocks | CS-M-54946 | 58725-33-0 | Enquire |
| 1-[(2R)-3-Hydroxy-2-methyl-1-oxopropyl]-L-proline | Building Blocks | CS-T-56218 | 613256-52-3 | Enquire |
| 1-[(2S)-3-(Acetylthio)-2-methylpropionyl]-L-proline | Building Blocks | CS-O-32312 | 64838-55-7 | Enquire |
| 1-[N2,N6-Bis[(phenylmethoxy)carbonyl]-L-lysyl]-L-proline Phe... | Building Blocks | CS-T-67730 | 145435-28-5 | Enquire |
| 1-L-Prolyl-L-proline Hydrochloride | Building Blocks | CS-ED-42209 | 76932-06-4 | Enquire |
| 3,4-Dehydro-L-proline Hydrochloride | Building Blocks | CS-T-73383 | 201469-31-0 | Enquire |
| 3-Allohydroxy-L-proline;cis-3-Hydroxy-L-proline; cis-3-Hydro... | Building Blocks | CS-DV-02096 | 567-35-1 | Enquire |
| Biocytin-L-proline | Building Blocks | CS-T-49113 | 1356931-03-7 | Enquire |
| Biocytin-N-(t-boc)-L-proline | Building Blocks | CS-T-49112 | 1356383-21-5 | Enquire |
| Boc-L-proline methyl ester | Building Blocks | CS-DB-00032 | 59936-29-7 | Enquire |
| boc-trans-Hydroxy-L-proline | Building Blocks | CS-T-28484 | 13726-69-7 | In Stock |
| cis-4-Hydroxy-L-proline | Building Blocks | CS-T-28447 | 618-27-9 | Enquire |
| cis-4-Hydroxy-L-proline Methyl Ester Hydrochloride | Building Blocks | CS-T-78918 | 40126-30-5 | Enquire |
| L-Lysyl-L-proline | Building Blocks | CS-T-57344 | 52766-27-5 | In Stock |
| L-Proline, methyl ester | Building Blocks | CS-O-47363 | 2577-48-2 | Enquire |
| N-(tert-Butoxycarbonyl)-L-proline | Building Blocks | CS-T-49551 | 15761-39-4 | Enquire |
| N6-Trifluoroacetyl-L-lysyl-L-proline | Building Blocks | CS-T-88014 | 103300-89-6 | Enquire |
| N-acetyl-4-oxo-L-proline | Building Blocks | CS-O-13059 | 76868-78-5 | Enquire |
| N-Acetyl-L-proline | Building Blocks | CS-O-30988 | 68-95-1 | In Stock |
| N-Boc-alpha-methyl-l-proline | Building Blocks | CS-DL-00112 | 103336-06-7 | Enquire |
| N-Boc-trans-4-amino-L-proline methyl ester | Building Blocks | CS-AC-04713 | 121148-00-3 | Enquire |
| N-Carbobenzoxy-l-proline tert-butyl ester | Building Blocks | CS-T-70241 | 16881-39-3 | Enquire |
| N-Cbz-cis-4-hydroxy-l-proline methyl ester | Building Blocks | CS-T-70357 | 57653-35-7 | Enquire |
| N-CBZ-Glycyl-L-proline 7-Amido-4-methylcoumarin | Building Blocks | CS-T-68993 | 68542-93-8 | Enquire |
| N-Phenacetyl-L-proline | Building Blocks | CS-O-56958 | 2752-38-7 | Enquire |
| trans-4-Hydroxy-1-L-phenylalanyl-L-proline | Building Blocks | CS-T-78088 | 90965-82-5 | Enquire |
| trans-4-Methyl-L-proline Hydrochloride | Building Blocks | CS-T-34243 | 365280-18-8 | Enquire |