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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Levothyroxine, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Levothyroxine impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Levothyroxine-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Levothyroxine Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Levothyroxine-d3 Stable Isotopes CS-O-16186 Not Available In Stock
Levothyroxine- 13C6 Stable Isotopes CS-O-38573 Not Available Enquire
Levothyroxine- D5 Stable Isotopes CS-O-38575 Not Available Enquire
Levothyroxine Sodium Hydrate Stable Isotopes CS-SS-25628-100MG 25416-65-3 Enquire
Levothyroxine-13C9-15N Stable Isotopes CS-O-03203 1431868-11-9 Enquire


API

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Levothyroxine API CS-BB-00023 51-48-9 In Stock
Levothyroxine Sodium API CS-O-01770 55-03-8 In Stock
Levothyroxine Sodium Hydrate API CS-O-16243 25416-65-3 In Stock
Liothyronine sodium API CS-O-30971 55-06-1 In Stock
Thyroxine Sodium API CS-O-02455 55-03-8 In Stock
D-Thyroxine API CS-T-62056 51-49-0 Enquire


Metabolite

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Levothyroxine N-Methylamide Metabolite CS-O-14502 2088032-52-2 Enquire
N-Acetyl L-Thyroxine Ethyl Ester Metabolite CS-T-01207 30804-52-5 Enquire


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
*Levothyroxine Impurity CS-T-44338 32180-11-3 In Stock
2-hydroxy-2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodopheny... Impurity CS-O-34041 1421272-67-4 In Stock
3,3’,5,5’-Tetraiodothyronamine Hydrochloride Impurity CS-T-86207 788824-71-5 In Stock
3,5,3',5'-Tetraiodo Thyromandelic Acid Impurity CS-T-61906 93647-48-4 In Stock
3'-Bromo-3,5,5'-triiodothyronine Impurity CS-O-45711 77667-01-7 Enquire
D-Triiodothyronin Impurity CS-O-48805 5714-08-9 Enquire
levothyroxine Dimer Impurity CS-O-45712 2088032-62-4 Enquire
Levothyroxine Dimer 2 Impurity CS-O-34272 1425050-65-2 (Racemic) In Stock
Levothyroxine dimer-1 Impurity CS-O-34262 2086257-72-7 (Racemic) In Stock
Levothyroxine EP Impurity B Impurity CS-O-15811 1628720-66-0 In Stock
Levothyroxine EP Impurity C Impurity CS-T-45488 51-24-1 In Stock
Levothyroxine EP Impurity D Impurity CS-T-43890 67-30-1 In Stock
Levothyroxine EP Impurity E Impurity CS-T-19369 1041-01-6 In Stock
Levothyroxine EP Impurity F Impurity CS-T-62058 911661-90-0 In Stock
Levothyroxine EP Impurity G Hydrochloride Impurity CS-O-33624 2230724-39-5 (Freebase) In Stock
Levothyroxine EP Impurity H Impurity CS-T-43894 2055-97-2 In Stock
Levothyroxine EP Impurity I Impurity CS-T-43892 2016-06-0 In Stock
Levothyroxine EP Impurity K Impurity CS-O-14067 5817-39-0 In Stock
Levothyroxine Ethyl Ester Impurity CS-T-44337 76353-71-4 In Stock
Levothyroxine Gallic acid adduct Impurity CS-O-54445 ---- Enquire
Levothyroxine Glucose Adduct Impurity CS-P-08177 ---- In Stock
Levothyroxine Lactose Adduct Impurity CS-P-08082 Not Available In Stock
Levothyroxine Lactose Adduct (N-lactoside) Impurity CS-O-35442 Not Available Enquire
Levothyroxine Monochloro Impurity Impurity CS-O-16035 909279-46-5 In Stock
Levothyroxine Related Compound 10 Impurity CS-P-08124 94345-95-6 Enquire
Levothyroxine Sodium EP Impurity J Impurity CS-I-00089 70-40-6 In Stock
Levothyroxine stearic acid impurity 1 Impurity CS-O-53552 ---- Enquire
Levothyroxine stearic acid impurity 2 Impurity CS-O-53553 ---- Enquire
Levothyroxine-4-Lactose Maillard Impurity Impurity CS-O-50307 Not Available Enquire
Levothyroxine-alpha-hydroxymethy-impurity Impurity CS-O-34260 2086257-60-3 In Stock
methyl 2-hydroxy-2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diio... Impurity CS-O-34040 2086266-85-3 In Stock
O-(4-Hydroxy-3-iodophenyl) Levothyroxine Impurity CS-EO-03977 " 2086274-34-0" Enquire
T4-Formic Acid-N-methylamide Impurity CS-T-87948 2088032-78-2 In Stock
TRIIODO-L-THYRONINE AMPOLA 100 µG/ML Impurity CS-O-48172 5817-39-0 Enquire
α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methy... Impurity CS-T-78995 2088032-68-0 In Stock
3,3-Diiodo-L-thyronine Impurity CS-T-53273 4604-41-5 Enquire
3,5,3',5'-Tetraiodo Thyrolactic Acid Impurity CS-T-61905 7069-47-8 Enquire
3,5-Diiodo Thyroaldehyde Impurity CS-T-19364 2828-49-1 Enquire
3′,5′-Diiodothyronine Impurity CS-T-19370 4192-14-7 Enquire
3-Bromo-L-thyroxine Impurity CS-T-93287 1798894-90-2 Enquire
3-monoiodothyronine Impurity CS-O-42036 16170-92-6 Enquire
Levothyroxine Impurity 30 Sodium Salt Impurity CS-P-08125 Not Available Enquire
Levothyroxine- Impurity 5 Impurity CS-DN-00016 Not Available Enquire
Levothyroxine- Impurity NMP Impurity CS-DN-00015 Enquire
Levothyroxine Lactose Adduct (O-lactoside) Impurity CS-O-35443 Not Available Enquire
Levothyroxine N- formamide Impurity Impurity CS-DN-00017 Not Available Enquire
β-Hydroxy Thyroxine Impurity CS-T-56505 107849-54-7 Enquire


Intermediate

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
N-Formyl Thyroxine Intermediate CS-T-24771 671235-41-9 In Stock


Glucuronide

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Levothyroxine Mannitol Adduct Glucuronide CS-O-53867 ---- Enquire


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
3,3',5-Triiodo Thyropropionic Acid Fine Chemicals CS-T-62409 51-26-3 Enquire
Levothyroxine disodium salt Fine Chemicals CS-O-34227 502481-31-4 Enquire
O-(4-Hydroxy-3-iodo-5-nitrophenyl)-3,5-diiodo-L-tyrosine Fine Chemicals CS-O-36443 105172-64-3 Enquire


Secondary Standards

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Levothyroxine Secondary Standards CS-SS-24584-1GM 51-48-9 Enquire