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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Linagliptin, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Linagliptin impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Linagliptin-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Linagliptin Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
3-Deamino 3-Hydroxy Linagliptin-d3 Stable Isotopes CS-T-100569 1620278-39-8 (Unlabeled) Enquire
Linagliptin Acetamide-d3 Stable Isotopes CS-O-45658 Not Available In Stock
Linagliptin D5 Stable Isotopes CS-O-49797 668270-12-0 (Unlabelled) Enquire
Linagliptin D6 Stable Isotopes CS-O-49798 668270-12-0 (Unlabelled) Enquire
Linagliptin-13C-d3 Stable Isotopes CS-EO-00817 1398044-43-3 Enquire
Linagliptin-d3 Stable Isotopes CS-TB-80231 1398044-48-8 In Stock
Linagliptin-d4 Stable Isotopes CS-O-06724 2140263-92-7 In Stock


API Standards

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Linagliptin API Standards CS-O-30970 668270-12-0 In Stock


Metabolites

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Linagliptin Metabolite CD1790 Metabolites CS-P-08365 2803369-89-1 In Stock


Impurities

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(4-​Methylquinazolin-​2-​yl)​methanol Impurities CS-AQ-00174 13535-91-6 In Stock
(E)-4-styryl Linagliptin Impurity Impurities CS-O-45908 Not Available Enquire
(R)-3-Boc-Aminopiperidine Impurities CS-O-31218 309956-78-3 In Stock
(R)-8-(3-aminopiperidin-1-yl)-1-(but-2-yn-1-yl)-3-methyl-7-(... Impurities CS-O-43292 Not Available Enquire
(R)-8-(3-aminopiperidin-1-yl)-7-(4-hydroxybut-2-yn-1-yl)-3-m... Impurities CS-O-34950 1807608-59-8 Enquire
(Z)-4-styryl Linagliptin Impurity Impurities CS-O-45909 Not Available Enquire
1H-Purine-2,6-dione, 8-[(3R)-3-amino-1-piperidinyl]-3,9-dihy... Impurities CS-O-48008 2382729-41-9 Enquire
2-Chloromethyl-3-oxo-4-methyl quinazoline Impurities CS-O-40456 6640-59-1 Enquire
3-Deamino 3-Hydroxy Linagliptin Impurities CS-SN-00141 1620278-39-8 In Stock
7-(But-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione Impurities CS-O-14821 586408-08-4 In Stock
7-des-2-butyn-7-methyl 3-Deamino 3-Hydroxy Linagliptin Impurities CS-O-58823 Not Available Enquire
7-des-2-butyn-7-methyl 3-Deamino 3-Hydroxy Linagliptin (S-is... Impurities CS-O-58822 Not Available Enquire
7-des-2-butyn-7-methyl Linagliptin Impurities CS-O-58150 1339955-47-3 In Stock
7-des-2-butyn-7-methyl Linagliptin (S-isomer) Impurities CS-O-58821 Not Available Enquire
8-Bromo-3-methyl-7-((4-methylquinazolin-2-yl)methyl)-1H-puri... Impurities CS-AQ-00162 2749405-42-1 In Stock
8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine] Impurities CS-O-31413 666816-98-4 In Stock
8-Bromo-7-(but-2-en-1-yl)-3-methyl-6-((4-methylquinazolin-2-... Impurities CS-O-44888 Not Available Enquire
Bromobutene Linagliptin impurity VII Impurities CS-O-15765 1446263-39-3 In Stock
Desalkyl N-nitroso Linagliptin Impurities CS-O-42245 Not Available Enquire
Desbutyl N-nitroso Linagliptin impurity 16 Impurities CS-O-46605 Not Available Enquire
Desbutyl N-nitroso Linagliptin Impurity 52 Impurities CS-O-46607 Not Available Enquire
Hydroxy Methyl Linagliptin Impurities CS-EO-01211 Not Available In Stock
Linagliptin 8-Bromo Impurity Impurities CS-O-32157 93703-24-3 In Stock
linagliptin butane impurity Impurities CS-O-45868 Not Available In Stock
Linagliptin Diene Impurity Impurities CS-EO-02289 2463617-43-6 Enquire
Linagliptin Dimer (Racemic Mixture) Impurities CS-O-41600 2759280-92-5 Enquire
Linagliptin Dimer Impurity Impurities CS-EO-01615 Not Available Enquire
Linagliptin Dimer impurity (N-C-C-C Dimer) Impurities CS-O-39903 2463617-49-2 Enquire
Linagliptin Dimer Impurity 3 Impurities CS-O-56527 Not Available Enquire
Linagliptin Dimer Impurity 4 Impurities CS-EO-03973 Not Available Enquire
Linagliptin Dimer Impurity 5 Impurities CS-O-56530 Not Available Enquire
Linagliptin Dimer Impurity 6 Impurities CS-O-56526 1643364-41-3 Enquire
Linagliptin Ethyldimer Impurities CS-T-94240 Not Available Enquire
Linagliptin Glycosamine Impurities CS-O-49726 Not Available Enquire
Linagliptin Hydroxy Impurity Impurities CS-O-47958 Not Available In Stock
Linagliptin Impurity 1 Impurities CS-O-14113 Not Available Enquire
Linagliptin Impurity 106 Impurities CS-O-45910 Not Available Enquire
Linagliptin impurity 115 Impurities CS-O-52277 Not Available Enquire
Linagliptin Impurity 117 Impurities CS-O-52278 Not Available Enquire
Linagliptin impurity 14 Impurities CS-EO-00296 2253964-98-4 In Stock
Linagliptin Impurity 17 Impurities CS-EO-01092 2489212-72-6 In Stock
Linagliptin Impurity 2 Impurities CS-O-14120 Not Available Enquire
Linagliptin Impurity 20 Impurities CS-O-43293 2514949-81-4 In Stock
Linagliptin Impurity 23 Impurities CS-O-56532 Not Available Enquire
Linagliptin Impurity 24 Impurities CS-O-56534 Not Available Enquire
Linagliptin Impurity 25 Impurities CS-EO-02102 Not Available Enquire
Linagliptin Impurity 26 Impurities CS-O-56536 Not Available Enquire
Linagliptin Impurity 28 Impurities CS-O-56539 Not Available Enquire
Linagliptin Impurity 29 Impurities CS-EO-00109 Not Available Enquire
Linagliptin Impurity 3 Impurities CS-O-14121 668269-51-0 In Stock
Linagliptin Impurity 30 Impurities CS-P-08375 1573118-33-8 In Stock
Linagliptin Impurity 31 Impurities CS-O-56549 Not Available In Stock
Linagliptin Impurity 4 Impurities CS-O-14122 1638744-06-5 Enquire
Linagliptin Impurity 41 Impurities CS-O-39218 2074688-84-7 In Stock
Linagliptin Impurity 44 Impurities CS-AQ-00168 1791405-13-4 In Stock
Linagliptin Impurity 46 Impurities CS-O-58224 Not Available Enquire
Linagliptin Impurity 49 Impurities CS-EO-01850 2468656-63-3 In Stock
Linagliptin Impurity 5 Impurities CS-EO-00108 2253964-85-9 In Stock
Linagliptin Impurity 6 TriHCl Impurities CS-O-53849 1418133-47-7(Free base) Enquire
Linagliptin Impurity 75 HCl salt Impurities CS-EO-02803 Not Available Enquire
Linagliptin Impurity 76 TrisHCl salt Impurities CS-EO-03191 Not Available Enquire
Linagliptin Impurity 9 Impurities CS-EO-02062 Not Available Enquire
Linagliptin Impurity B Impurities CS-O-54249 2138392-83-1 In Stock
Linagliptin impurity C Impurities CS-AQ-00163 Not Available Enquire
Linagliptin Impurity D Impurities CS-AQ-00164 Not Available In Stock
Linagliptin Impurity E Impurities CS-AQ-00165 1446263-38-2 In Stock
Linagliptin Impurity F Impurities CS-AQ-00166 2416949-69-2 In Stock
Linagliptin Impurity G Impurities CS-AQ-00167 668270-11-9 In Stock
Linagliptin Impurity I Impurities CS-EO-02162 Not Available Enquire
Linagliptin Impurity II Impurities CS-EO-02163 Not Available Enquire
Linagliptin Impurity J Impurities CS-AQ-00170 2436762-89-7 In Stock
Linagliptin Impurity K Impurities CS-AQ-00171 Not Available In Stock
Linagliptin Impurity M Impurities CS-AQ-00173 216854-24-9 In Stock
Linagliptin Impurity N Impurities CS-EO-01093 Not Available Enquire
Linagliptin Impurity O Impurities CS-AQ-00175 2518331-40-1 In Stock
Linagliptin Impurity P Impurities CS-AQ-00176 2748381-67-9 In Stock
Linagliptin Impurity Q Impurities CS-AQ-00177 1673546-62-7 In Stock
Linagliptin impurity R Impurities CS-AQ-00178 1646355-34-1 In Stock
Linagliptin Impurity S Impurities CS-AQ-00179 2279114-31-5 In Stock
Linagliptin Impurity T Impurities CS-AQ-00180 2279114-27-9 In Stock
Linagliptin Impurity U Impurities CS-AQ-00181 666816-91-7 In Stock
Linagliptin Impurity V Impurities CS-AQ-00182 Not Available In Stock
Linagliptin Impurity W Impurities CS-AQ-00183 6140-11-0 In Stock
Linagliptin Impurity X Impurities CS-AQ-00184 668273-74-3 In Stock
Linagliptin Impurity Y Impurities CS-AQ-00185 2428491-17-0 In Stock
Linagliptin Impurty VII Impurities CS-EO-00358 Not Available In Stock
Linagliptin Lactose Adduct Impurities CS-O-57459 Not Available Enquire
Linagliptin Methyldimer Impurities CS-O-15699 1418133-47-7 In Stock
Linagliptin N-Acetyl Impurity Impurities CS-O-15822 1803079-49-3 In Stock
Linagliptin Pentahydroxy Impurity Impurities CS-O-14234 Not Available Enquire
Linagliptin quinazolin Dimer Impurities CS-O-49147 2469626-53-5 Enquire
Linagliptin Stereochemical Impurity Impurities CS-O-55596 1383917-84-7 Enquire
Linagliptin Tartaric Acid Impurity Impurities CS-O-56558 Not Available Enquire
Linagliptin tert-butyl carbamate Impurities CS-O-50591 Not Available Enquire
Linagliptin(R,S) N,N'-Methylene Dimer Impurities CS-O-53612 Not Available Enquire
Linagliptin-4-methylquinazolin-2-yl-methyl dimer Impurities CS-T-102502 Not Available In Stock
Linagliptine Chloro Impurity Impurities CS-O-45083 Not Available Enquire
N-(2-acetylphenyl)-3-Hydroxy Linagliptin impurity Impurities CS-O-58825 Not Available In Stock
N-(2-acetylphenyl)-3-Hydroxy Linagliptin impurity (S-isomer) Impurities CS-O-58824 Not Available In Stock
N-(6-Amino-1,2,3,4-tetrahydro-1-methyl-2,4-dioxo-5-pyrimidin... Impurities CS-O-41334 14785-95-6 Enquire


Intermediates

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(R)-1-((4-methylquinazolin-2-yl)methyl)piperidin-3-amine Intermediates CS-SN-00142 Not Available Enquire
1-[(4-Methylquinazolin-2-yl)methyl)]-3-methyl-7-(2-butin-1-y... Intermediates CS-O-31412 853029-57-9 In Stock
2-(chloromethyl)-4-methylquinazoline Intermediates CS-O-31217 109113-72-6 In Stock
tert-butyl (R)-(1,5-dihydroxypentan-2-yl)carbamate Intermediates CS-O-41335 397246-12-7 Enquire


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
3-(2-Cyanoacetyl)-1-methylurea Fine Chemicals CS-N-05166 6972-77-6 In Stock
Linagliptin Methyldimer Fine Chemicals CS-TB-80232 Not Available Enquire
Linagliptin N-Aminoacyl Impurity Fine Chemicals CS-ZB-33371 1955514-80-3 Enquire