Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Nebivolol, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Nebivolol impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Nebivolol-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Our Nebivolol-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Nebivolol Related Compounds
Stable Isotopes
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (+)-Nebivolol-D3 | Stable Isotopes | CS-O-52962 | ---- | Enquire |
| (+)-Nebivolol-d4 Hydrochloride | Stable Isotopes | CS-T-97271 | Not Available | Enquire |
| 4-Hydroxy Nebivolol Hydrochloride-d4(Mixture of Diastereomer... | Stable Isotopes | CS-T-100188 | Not Available | Enquire |
| Nebivolol (RSSS) -D4 | Stable Isotopes | CS-O-49966 | 2124271-47-0 | Enquire |
| Nebivolol(SRRR)-D4 | Stable Isotopes | CS-O-49967 | 118457-15-1(Unlabelled) | Enquire |
| Nebivolol-d4 (Mixture of Isomers) | Stable Isotopes | CS-O-02703 | 118457-14-0(Unlabeled) | Enquire |
| Nebivolol-d4-O-D-Glucuronide (Mixture of Diastereomers) | Stable Isotopes | CS-O-36105 | Not Available | Enquire |
| N-Nitroso rac-Nebivolol-d4 | Stable Isotopes | CS-EO-02554 | 1391051-68-5 (Unlabeled) | In Stock |
| rac N-Benzyl Nebivolol-d4 | Stable Isotopes | CS-T-101841 | 1246814-48-1 | Enquire |
| rac Nebivolol-d8 Hydrochloride | Stable Isotopes | CS-T-99951 | Not Available | Enquire |
| rac-Nebivolol-d4 (Major) | Stable Isotopes | CS-T-95143 | 1219407-55-2 | In Stock |
| rac-Nebivolol-D6 | Stable Isotopes | CS-F-00256 | 2824330-68-7 | Enquire |
| (-)-Nebivolol-d4 Hydrochloride | Stable Isotopes | CS-T-95142 | Not Available | Enquire |
| rac Nebivolol D8 | Stable Isotopes | CS-T-59198 | 1219166-00-3 | Enquire |
| R-Nebivolol D4 HCl | Stable Isotopes | CS-O-16072 | 152520-56-4(Unlabeled) | Enquire |
API
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Nebivolol Hydrochloride | API | CS-O-00204 | 152520-56-4 | In Stock |
| Rac-Nebivolol | API | CS-O-01942 | 99200-09-6 | In Stock |
| Rel-Nebivolol | API | CS-O-16279 | 118457-14-0 | Enquire |
Metabolite
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| 4-Hydroxy Nebivolol | Metabolite | CS-O-20047 | 178383-76-1 | In Stock |
| Nebivolol Aromatic-monohydroxy metabolite | Metabolite | CS-O-45017 | 178383-77-2 | Enquire |
| 4-Hydroxy Nebivolol | Metabolite | CS-O-03668 | 178383-76-1 | Enquire |
| Nebivolol dealkylated carboxylic acid | Metabolite | CS-O-52964 | ---- | Enquire |
Impurity
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (+)-Nebivolol | Impurity | CS-T-82884 | 118457-15-1 | Enquire |
| (2S,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane | Impurity | CS-T-76125 | 197706-51-7 | Enquire |
| (R,R,S,S)-Nebivolol | Impurity | CS-T-83044 | 1360598-84-0 | Enquire |
| (R,S,R,S)-Nebivolol | Impurity | CS-T-83415 | 119365-24-1 | Enquire |
| (S,R,R,S)-Nebivolol | Impurity | CS-T-59200 | 119365-23-0 | Enquire |
| 2-(oxiran-2-yl)chromane | Impurity | CS-EO-03981 | 99199-99-2 | Enquire |
| 2-chloro-1-(6-fluorochroman-2-yl)ethan-1-one | Impurity | CS-EO-03050 | 943126-72-5 | Enquire |
| Defluoro Nebivolol | Impurity | CS-T-51727 | 129101-34-4 | In Stock |
| Didefluoro Nebivolol | Impurity | CS-O-31098 | 129101-33-3 | In Stock |
| N-Benzyl (-)-Nebivolol | Impurity | CS-T-48936 | 1199945-26-0 | In Stock |
| Nebivolol Des floro impurity of isomer B | Impurity | CS-O-59744 | 1426139-40-3 | Enquire |
| Nebivolol EP Impurity D | Impurity | CS-EO-01803 | Not Available | In Stock |
| NEBIVOLOL ETHYL CARBONYL CARBONATE | Impurity | CS-O-52455 | Not Available | Enquire |
| Nebivolol HCL unwanted isomer Impurity | Impurity | CS-O-42580 | Not Available | Enquire |
| Nebivolol Impurity (RSRR+SRSS) | Impurity | CS-O-46314 | ---- | Enquire |
| Nebivolol Impurity 10 (RS,SR) | Impurity | CS-P-01831 | 920275-23-6 | Enquire |
| Nebivolol Impurity 11 (SR,SR) | Impurity | CS-P-01832 | Not Available | Enquire |
| Nebivolol Impurity 12 | Impurity | CS-EO-01101 | 119365-29-6 | Enquire |
| Nebivolol Impurity 14 | Impurity | CS-O-15361 | 213132-06-0 | Enquire |
| Nebivolol Impurity 17 (RS,SR) | Impurity | CS-EO-01100 | 119365-30-9 | Enquire |
| Nebivolol Impurity 2 HCl (SR,RS) | Impurity | CS-P-01823 | 920275-19-0 | Enquire |
| Nebivolol Impurity 20 (SS,SS) | Impurity | CS-EO-01102 | 119365-28-5 | Enquire |
| Nebivolol Impurity 3 (RRSS) (HCl) | Impurity | CS-EO-03721 | 1360598-84-0 (Freebase) | Enquire |
| Nebivolol Impurity 40 (SRSS) | Impurity | CS-EO-03723 | 129101-35-5 | Enquire |
| Nebivolol Impurity 5 | Impurity | CS-P-01826 | 99199-91-4 | In Stock |
| Nebivolol Impurity 5 (RRSR) (HCl) | Impurity | CS-EO-03722 | 920275-20-3 | Enquire |
| Nebivolol Impurity 53 | Impurity | CS-O-60587 | ---- | Enquire |
| Nebivolol Impurity A | Impurity | CS-O-05763 | 118457-16-2 | In Stock |
| Nebivolol Isomer-I | Impurity | CS-O-05744 | ---- | In Stock |
| Nebivolol isomers (RSRS+RSSR+SRRS) | Impurity | CS-O-51835 | 2415933-03-6+119365-30-9+119365-23-0 | In Stock |
| Nebivolol RRRS isomer | Impurity | CS-EO-03958 | 1030385-17-1 | Enquire |
| Nebivolol RSSS Isomer | Impurity | CS-O-44921 | Not Available | Enquire |
| N-Formyl Nebivolol | Impurity | CS-SN-00106 | Not Available | In Stock |
| rel-Desfluoro Nebivolol Impurity | Impurity | CS-O-33834 | 1416402-13-5 | Discontinued |
| (1'S,2S)-2-(2'-Tosyl-1',2'-dihydroxyethyl)-6-fluorochromane | Impurity | CS-T-62161 | 905454-58-2 | Enquire |
| 2,2'-(Benzylazanediyl)bis(1-(6-fluorochroman-2-yl)ethan-1-ol... | Impurity | CS-O-41082 | Not Available | Enquire |
| Defluoro Nebivolol (Mixture of Diastereomers) | Impurity | CS-T-73691 | Not Available | Enquire |
| Nebivolol Hydrochloride At RRT 0.88 | Impurity | CS-O-46803 | Not Available | Enquire |
| Nebivolol Hydrochloride At RRT 1.13 | Impurity | CS-O-46804 | Not Available | Enquire |
| Nebivolol Impurity (RRSR+RSRR) | Impurity | CS-O-36196 | Not Available | Enquire |
| Nebivolol Impurity (SSRS+SRSS) | Impurity | CS-O-36197 | Not Available | Enquire |
| Nebivolol impurity 1 | Impurity | CS-O-37097 | 1696430-22-4 | Enquire |
| Nebivolol Impurity 1 (RR,SS) | Impurity | CS-P-01822 | Not Available | Enquire |
| Nebivolol Impurity 12 (RR,RR) | Impurity | CS-P-01833 | 920275-25-8 | Enquire |
| Nebivolol Impurity 13 (SS,SS) | Impurity | CS-P-01834 | 920275-27-0 | Enquire |
| Nebivolol Impurity 26 | Impurity | CS-EO-00055 | 1803397-45-6 | Enquire |
| Nebivolol Impurity 3 | Impurity | CS-P-01824 | 1029684-20-5 | Enquire |
| Nebivolol Impurity 34 (RSRR+RRRR) | Impurity | CS-EO-00543 | Not Available | Enquire |
| Nebivolol Impurity 4 | Impurity | CS-P-01825 | 129050-29-9 | Enquire |
| Nebivolol Impurity 6 (SS) | Impurity | CS-P-01827 | Not Available | Enquire |
| Nebivolol Impurity 7 (RR) | Impurity | CS-P-01828 | Not Available | Enquire |
| Nebivolol Impurity 8 (SR) | Impurity | CS-P-01829 | Not Available | Enquire |
| Nebivolol Impurity 9 (RS) | Impurity | CS-P-01830 | Not Available | Enquire |
| Nebivolol Impurity B (SR,SS) | Impurity | CS-EO-00284 | 119365-25-2 | Enquire |
| Nebivolol Isomer (SRSR+RSRS) | Impurity | CS-O-34427 | Not Available | Enquire |
| Nebivolol isomers - RSRR | Impurity | CS-O-34513 | Not Available | Enquire |
| Nebivolol lactose adduct | Impurity | CS-O-16769 | Not Available | Enquire |
| Nebivolol Peak Identification containing Impurity A | Impurity | CS-EG-03420 | ---- | Enquire |
| Nebivolol Peak Identification containing Impurity B | Impurity | CS-EG-03421 | ---- | Enquire |
| Nebivolol Peak Identification containing Impurity D | Impurity | CS-EG-03422 | ---- | Enquire |
| Nebivolol Stereoisomer Mixture | Impurity | CS-O-46246 | Not Available | Enquire |
| rel-(S,R,S,S)-Nebivolol Hydrochloride | Impurity | CS-T-83172 | 1338823-20-3 | Enquire |
| rel-N-Benzyl Nebivolol | Impurity | CS-O-33749 | 876666-07-8 | Enquire |
Intermediate
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (2S)-2-(6-Fluoro-3,4-dihydro-2H-chromen-2-yl)-2-{[(4-methylp... | Intermediate | CS-O-50024 | 1345202-53-0 | Enquire |
| (8-fluorochroman-7-yl)methanol | Intermediate | CS-O-55386 | ---- | Enquire |
| 6-fluro-4-oxo-1benzopyran-2-carboxylic acid | Intermediate | CS-O-10635 | 99199-59-4 | In Stock |
| Nebivolol Ethanaol Impurity | Intermediate | CS-O-49235 | 1017878-67-9 | Enquire |
Glucuronide
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Nebivolol-O-beta-D-Glucuronide (Mixture of isomers) | Glucuronide | CS-O-30513 | 904917-24-4 | In Stock |
Fine Chemicals
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| 6-Fluorochromane-2-carboxylic acid | Fine Chemicals | CS-T-54821 | 99199-60-7 | In Stock |
Nitrosamine
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| N-nitroso Desfluoro Nebivolol | Nitrosamine | CS-O-51270 | Not Available | Enquire |
| N-Nitroso Nebivolol (Mixture of Diastereomers) | Nitrosamine | CS-T-83669 | 1391051-68-5 | In Stock |
| N-Nitroso Nebivolol Impurity 5 | Nitrosamine | CS-O-52670 | Not Available | In Stock |
| N-Nitroso Nebivolol | Nitrosamine | CS-O-38892 | Not Available | Discontinued |
Secondary Standards
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Nebivolol Hydrochloride | Secondary Standards | CS-SS-25766 | 152520-56-4 | Enquire |
| Nebivolol Related Compound C | Secondary Standards | CS-SS-26249-50MG | 876514-31-7 | Enquire |
| Nebivolol Related Compound D | Secondary Standards | CS-SS-26234-100MG | 793669-26-8 | Enquire |
Analytical Standard
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| N-Nitroso Nebivolol (Mixture of Diastereomers) | Analytical Standard | CS-T-83669-10MG | 1391051-68-5 | Enquire |
| N-nitroso-nebivolol-100 PPM in Acetonitrile | Analytical Standard | CS-T-83669-1.5ML | 1391051-68-5 | Enquire |