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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Nicotine, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Nicotine impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Nicotine-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Nicotine Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(R)-Anabasine-d4 Stable Isotopes CS-T-94109 34366-21-7 (Unlabelled) Enquire
(R)-Nicotine-d3 N-β-D-Glucuronide Stable Isotopes CS-T-97265 Not Available Enquire
(R)-N'-Nitrosonornicotine-d4 Stable Isotopes CS-P-08860 61601-78-3 (Unlabelled) Enquire
(S)-Nicotine-d3 N-b-D-Glucuronide Stable Isotopes CS-T-97266 Not Available Enquire
Isonicotine-d3 Stable Isotopes CS-T-98780 1346601-08-8 Enquire
Mixture of  (R,S)-N-Nitroso Anabasine-d4, rac N’-Nitrosonorn... Stable Isotopes CS-T-98765 Not Available Enquire
N-Formylnornicotine-D4 Stable Isotopes CS-T-103948 3000-81-5(unlabelled) Enquire
Nicotine-d3 Stable Isotopes CS-O-06811 69980-24-1 In Stock
Nicotine-d3 N-(4-Deoxy-4,5-didehydro)-b-D-glucuronide Stable Isotopes CS-T-97267 Not Available Enquire
N-Nitrosonornicotine-2,4,5,6-d4(Pyridine-d4) Stable Isotopes CS-O-02685 66148-19-4 In Stock
rac-N’-Nitrosonornicotine-d4 1-N-Oxide Stable Isotopes CS-T-102179 Not Available Enquire
rac-Nicotine-d7 (N-methyl-d3; pyridine-d4) Stable Isotopes CS-T-94964 1219805-86-3 In Stock


API

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(S)-(-)-Nicotine API CS-T-36553 54-11-5 In Stock
(S)-Anabasine API CS-T-48180 494-52-0 In Stock
Isonicotinamide API CS-T-29786 1453-82-3 In Stock
Nicotine lactate API CS-ED-41628 14474-00-1 Enquire
Nicotine Malate API CS-T-96130 73057-36-0 Enquire
Myosmine API CS-M-05066 532-12-7 Enquire


Metabolite

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Nicotinuric Acid Metabolite CS-O-03508 583-08-4 In Stock


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(1'R,2'S)-Nicotine 1'-Oxide Impurity CS-EO-02161 51020-67-8 Enquire
(S)-Nicotine-N-oxide Impurity CS-EU-00053 491-26-9 In Stock
Benzyl nicotinate Impurity CS-CG-00214 94-44-0 In Stock
Ethyl Nicotinate HCl Impurity CS-EO-03725 65550-28-9 Enquire
Nicotine Related Compound D Impurity CS-O-45829 532-12-7 (Freebase) Enquire
Nicotine Related Compound E Impurity CS-O-45830 491-26-9 (Freebase) In Stock
Rac-Anabasine DiHCl Impurity CS-EO-03726 143924-48-5 Enquire
(2'S)-Nicotine 1-Oxide Impurity CS-T-59271 2820-55-5 Enquire
(S)-Nornicotine Impurity CS-T-59752 494-97-3 Enquire
N-Ethyl (S)-Nornicotine Impurity CS-T-74733 5979-92-0 Enquire
R-(R)-Nicotine Impurity CS-T-59261 25162-00-9 Enquire


Glucuronide

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Nicotine-β-D-Glucuronide Glucuronide CS-T-59270 153536-53-9 Enquire


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Nicotine Hydrogen Tartrate Fine Chemicals CS-T-82860 65-31-6 Enquire


Nitrosamine

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(2S)-N'-Nitrosonornicotine Nitrosamine CS-T-37266 16543-55-8 In Stock
(R,S)-N-Nitroso Anabasine HCl salt Nitrosamine CS-EO-03727 37620-20-5 (Freebase) Enquire
rac-N-Nitroso Nornicotine Nitrosamine CS-T-37265 80508-23-2 In Stock


Therapeutic

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Methyl nicotinate Therapeutic CS-T-34479 93-60-7 In Stock
Nicotine Ditartrate Dihydrate Therapeutic CS-O-30688 6019-06-3 In Stock


Chiral

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(S)-(-)-Anatabine Chiral CS-T-03776 581-49-7 Enquire