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Ribociclib Related Compounds

Analytical Standard

COMPOUNDCATEGORYCAT. No.CAS. No.ACTIONS
X Structure - N-nitroso-ribociclib-1-100 PPM in Acetonitrile

N-nitroso-ribociclib-1-100 PPM in Acetonitrile
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Analytical Standard CS-EO-02074-1.5ML Not Available
X Structure - N-nitroso-ribociclib-2-100 PPM in Acetonitrile

N-nitroso-ribociclib-2-100 PPM in Acetonitrile
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Analytical Standard CS-EO-02069-1.5ML ----
X Structure - Ribociclib Nitroso Impurity 1

Ribociclib Nitroso Impurity 1
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Analytical Standard CS-EO-02074-10MG Not Available
X Structure - Ribociclib Nitroso Impurity 2

Ribociclib Nitroso Impurity 2
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Analytical Standard CS-EO-02069-10MG ----

API

COMPOUNDCATEGORYCAT. No.CAS. No.ACTIONS
X Structure - Ribociclib

Ribociclib
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API CS-T-30953 1211441-98-3
X Structure - Ribociclib Hydrobromide

Ribociclib Hydrobromide
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API CS-EO-03820 2209917-73-5
X Structure - Ribociclib hydrochloride

Ribociclib hydrochloride
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API CS-ED-41482 1211443-80-9
X Structure - Ribociclib Sulfate

Ribociclib Sulfate
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API CS-EO-03821 2209917-76-8

Impurity

COMPOUNDCATEGORYCAT. No.CAS. No.ACTIONS
X Structure - (2-((2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methoxy)-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methanol

(2-((2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)...
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Impurity CS-O-39613 Not Available
X Structure - 2,4,5-Tribromopyrimidine

2,4,5-Tribromopyrimidine
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Impurity CS-O-39914 1298101-40-2
X Structure - 2-Chloro-7-Cyclopentyl-7H-Pyrrolo[2,3-d]Pyrimidine-6-Carbaldehyde

2-Chloro-7-Cyclopentyl-7H-Pyrrolo[2,3-d]Pyrimidine-6-Carbald...
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Impurity CS-MM-67170 1211443-55-8
X Structure - 3-(2-((2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methoxy)-4-(cyclopentylamino)pyrimidin-5-yl)prop-2-yn-1-ol

3-(2-((2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-y...
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Impurity CS-O-39610 Not Available
X Structure - 5-Bromo-4-chloro-N-cyclopentylpyrimidin-2-amine

5-Bromo-4-chloro-N-cyclopentylpyrimidin-2-amine
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Impurity CS-O-39867 1823404-28-9
X Structure - 6-(Piperazin-1-yl)pyridin-3-amine

6-(Piperazin-1-yl)pyridin-3-amine
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Impurity CS-O-51247 119285-06-2
X Structure - N-(5-bromo-2-chloropyrimidin-4-yl)-N-cyclopentylnitrous amide

N-(5-bromo-2-chloropyrimidin-4-yl)-N-cyclopentylnitrous amid...
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Impurity CS-O-46944 Not Available
X Structure - N-formyl Ribociclib

N-formyl Ribociclib
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Impurity CS-EO-00477 2460732-08-3
X Structure - N-Nitroso Ribociclib Impurity 5

N-Nitroso Ribociclib Impurity 5
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Impurity CS-O-46945 Not Available
X Structure - N-Trityl Ribociclib Impurity

N-Trityl Ribociclib Impurity
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Impurity CS-O-49165 2524428-16-6
X Structure - Ribociclib acid impurity

Ribociclib acid impurity
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Impurity CS-EO-02244 2762182-61-4
X Structure - Ribociclib Chloro Amide Impurity

Ribociclib Chloro Amide Impurity
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Impurity CS-MM-67172 1211443-61-6
X Structure - Ribociclib Chloro Hydroxymethyl Impurity

Ribociclib Chloro Hydroxymethyl Impurity
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Impurity CS-O-32625 1374639-77-6
X Structure - Ribociclib Impurity 12

Ribociclib Impurity 12
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Impurity CS-SN-00154 2460738-27-4
X Structure - Ribociclib Impurity 13

Ribociclib Impurity 13
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Impurity CS-EO-04011 2460734-07-8
X Structure - Ribociclib Impurity 2

Ribociclib Impurity 2
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Impurity CS-O-34245 2069953-39-3
X Structure - Ribociclib Impurity 2 HCl salt

Ribociclib Impurity 2 HCl salt
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Impurity CS-EO-03819 2069953-39-3 (Freebase)
X Structure - Ribociclib Impurity 29

Ribociclib Impurity 29
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Impurity CS-EO-02243 ----
X Structure - Ribociclib Impurity 7

Ribociclib Impurity 7
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Impurity CS-O-32731 ----
X Structure - Ribociclib Impurity B

Ribociclib Impurity B
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Impurity CS-BL-00022 1374639-78-7
X Structure - Ribociclib impurity-1

Ribociclib impurity-1
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Impurity CS-O-32726 ----
X Structure - Ribociclib impurity-2

Ribociclib impurity-2
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Impurity CS-O-32727 Not Available
X Structure - Ribociclib impurity-3

Ribociclib impurity-3
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Impurity CS-O-32728 868591-58-6
X Structure - Ribociclib impurity-6

Ribociclib impurity-6
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Impurity CS-O-32730 1211441-59-6
X Structure - Ribociclib Mehyl Ester

Ribociclib Mehyl Ester
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Impurity CS-O-52695 3027550-97-3
X Structure - Ribociclib N-Oxide (Piperzine N-Oxide)

Ribociclib N-Oxide (Piperzine N-Oxide)
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Impurity CS-EO-00371 2514753-27-4
X Structure - Ribociclib N-Oxide Impurity 2

Ribociclib N-Oxide Impurity 2
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Impurity CS-O-54604 2470164-21-5
X Structure - Ribociclib open ring formamide impurity

Ribociclib open ring formamide impurity
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Impurity CS-O-52694 3027550-96-2
X Structure - Ribociclib succinate

Ribociclib succinate
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Impurity CS-T-93359 1374639-75-4
X Structure - Ribociclib Succinate Amine impurity

Ribociclib Succinate Amine impurity
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Impurity CS-O-49162 1331847-17-6
X Structure - Ribociclib Succinate Amino trityl impurity

Ribociclib Succinate Amino trityl impurity
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Impurity CS-O-49163 2524428-13-3
X Structure - Ribociclib Succinate Piperazine amide impurity

Ribociclib Succinate Piperazine amide impurity
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Impurity CS-O-49161 3056250-51-9
X Structure - Ribociclib Succinate Triphenyl isopropyl ether impurity

Ribociclib Succinate Triphenyl isopropyl ether impurity
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Impurity CS-O-49164 13594-78-0

Intermediate

COMPOUNDCATEGORYCAT. No.CAS. No.ACTIONS
X Structure - 5-Bromo-2-chloro-N-cyclopentylpyrimidin-4-amine

5-Bromo-2-chloro-N-cyclopentylpyrimidin-4-amine
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Intermediate CS-MM-11359 733039-20-8

Metabolite

COMPOUNDCATEGORYCAT. No.CAS. No.ACTIONS
X Structure - Ribociclib N-Desmethyl Metabolite HCl salt

Ribociclib N-Desmethyl Metabolite HCl salt
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Metabolite CS-EO-03818 1211441-59-6 (Freebase)
X Structure - Ribociclib N-hydroxy metabolite(M13,CC284)

Ribociclib N-hydroxy metabolite(M13,CC284)
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Metabolite CS-O-41421 ----

Nitrosamine

COMPOUNDCATEGORYCAT. No.CAS. No.ACTIONS
X Structure - 6-( 4-nitrosopiperazin-1-yl)pyridin-3-amine

6-( 4-nitrosopiperazin-1-yl)pyridin-3-amine
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Nitrosamine CS-O-55156 ----
X Structure - N,N-Dinitroso Oxo Ribociclib

N,N-Dinitroso Oxo Ribociclib
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Nitrosamine CS-O-48829 Not Available
X Structure - N-Nitroso N-Boc-Ribociclib

N-Nitroso N-Boc-Ribociclib
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Nitrosamine CS-O-55154 ----
X Structure - N-Nitroso Ribociclib Acid impurity

N-Nitroso Ribociclib Acid impurity
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Nitrosamine CS-O-51919 Not Available
X Structure - N-Nitroso Ribociclib N-oxobutanoic acid

N-Nitroso Ribociclib N-oxobutanoic acid
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Nitrosamine CS-O-55155 ----
X Structure - Ribociclib Nitroso Impurity 3

Ribociclib Nitroso Impurity 3
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Nitrosamine CS-EO-02070 ----
X Structure - Ribociclib Nitroso Impurity 4

Ribociclib Nitroso Impurity 4
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Nitrosamine CS-O-59934 ----

Nitroso

COMPOUNDCATEGORYCAT. No.CAS. No.ACTIONS
X Structure - Ribociclib Nitroso Impurity 1

Ribociclib Nitroso Impurity 1
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Nitroso CS-EO-02074 Not Available
X Structure - Ribociclib Nitroso Impurity 2

Ribociclib Nitroso Impurity 2
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Nitroso CS-EO-02069 ----

Stable Isotopes

COMPOUNDCATEGORYCAT. No.CAS. No.ACTIONS
X Structure - Ribociclib D6 Hydrochloride

Ribociclib D6 Hydrochloride
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Stable Isotopes CS-O-46807 Not Available
X Structure - Ribociclib-d6

Ribociclib-d6
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Stable Isotopes CS-O-32732 1328934-40-2
X Structure - Ribociclib-d8

Ribociclib-d8
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Stable Isotopes CS-O-32629 2167898-24-8