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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Thiophene, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Thiophene impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Thiophene-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Thiophene Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(Z)-N-(4-Ethyl-2-(ethylamino)thiazole-5-carbonyl)thiophene-2... Stable Isotopes CS-T-100327 Not Available Enquire
4-(2,6-Dichloroanilino)-3-thiopheneacetonitrile-13C Stable Isotopes CS-T-99290 2710628-39-8 Enquire
4-Benzyl- 2-thiophenecarboxylic Acid-d7 Stable Isotopes CS-T-96726 Not Available Enquire
4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenec... Stable Isotopes CS-T-99996 2983160-04-7 Enquire
4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenec... Stable Isotopes CS-T-99997 2983160-01-4 Enquire
5-[2-[(3-Chloro-2-hydroxypropyl)thio]-4-thiazolyl]-2-thiophe... Stable Isotopes CS-T-100613 Not Available Enquire
5-[Bis(2-ethoxy-2-oxoethyl)amino]-4-cyano-2-(methoxycarbonyl... Stable Isotopes CS-T-101816 Not Available Enquire
5-Chloro-N-methylthiophene-2-carboxamide-13C1,d3 Stable Isotopes CS-T-101692 Not Available Enquire
N,α-Dimethyl-3-thiopheneethanamine-d3 Stable Isotopes CS-T-99264 Not Available Enquire
N-[3-(1,2,3,6-Tetrahydro-1-methyl-d3-4-pyridinyl)-1H-indol-5... Stable Isotopes CS-T-99081 Not Available Enquire
Tribenzothiophene-d8 Major Stable Isotopes CS-T-97868 Not Available Enquire


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(2R,2'R)-dimethyl 2,2'-((thiophene-2,3-diylbis(ethane-2,1-di... Impurity CS-O-49802 Not Available Enquire
(2R,2'R)-dimethyl 2,2'-((thiophene-3,4-diylbis(ethane-2,1-di... Impurity CS-O-49801 Not Available Enquire
(2R,3S,4R,5R)-1-(3-(5-(4-fluorophenyl)thiophene-2-carbonyl)-... Impurity CS-O-36245 Not Available Enquire
(2S,2'R)-dimethyl 2,2'-((thiophene-2,5-diylbis(ethane-2,1-di... Impurity CS-O-49794 Not Available Enquire
(3-(4-Fluorophenoxy)-6-methoxy2-(4-methoxyphenyl)-1- benzoth... Impurity CS-O-38327 477762-74-6 Enquire
(R)-3-methyl-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl... Impurity CS-O-56385 3026845-89-3 Enquire
(R)-5-chloro-N-(4-(3-oxomorpholino)phenyl)-N-((2-oxooxazolid... Impurity CS-O-36040 1879903-65-7 Enquire
(S)-3-((1-methoxypropan-2-yl)amino)-4-methylthiophene-2-carb... Impurity CS-O-47006 Not Available Enquire
(S)-5-chloro-N-((2-oxo-3-phenyloxazolidin-5-yl)methyl)thioph... Impurity CS-O-44136 2376189-86-3 Enquire
(S)-5-chloro-N-(2,3-dihydroxypropyl)thiophene-2-carboxamide Impurity CS-O-44140 Not Available Enquire
(S)-N-((3-(4-acetamidophenyl)-2-oxooxazolidin-5-yl)methyl)-5... Impurity CS-O-37048 2422046-61-3 Enquire
2-(3-chloro-1-(naphthalen-1-yloxy)propyl)thiophene Impurity CS-O-44302 1104890-93-8 Enquire
2-(4-fluorophenyl)-5-(2-methyl-5-((2S,3R,4R,5S,6R)-3,4,5-tri... Impurity CS-O-42790 Not Available Enquire
2-(4-fluorophenyl)-5-(2-methylbenzyl)thiophene Impurity CS-O-15276 2005454-69-1 In Stock
2-(4-hydroxyphenyl)-1-benzothiophene-6-ol Impurity CS-O-32131 63676-22-2 Enquire
2-(5-iodo-2-methylbenzyl)-5-phenylthiophene Impurity CS-ED-01079 2444540-01-4 Enquire
2-(Bis(2-nitrophenyl)amino)-5-methylthiophene-3-carbonitrile Impurity CS-O-39722 Not Available Enquire
2,3-Dibromo-5-chlorothiophene Impurity CS-TB-29230 60404-19-5 Enquire
2,3-Dibromothiophene Impurity CS-M-04589 3140-93-0 Enquire
2-Chlorothiophene Impurity CS-M-01713 96-43-5 In Stock
2-THIOPHENECARBOXYLIC ACID HYDRAZIDE Impurity CS-DL-00542-1GM 2361-27-5 Enquire
3-methyl-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,... Impurity CS-O-56386 1613733-74-6 Enquire
3-Methylthiophene Impurity CS-T-35178 616-44-4 Enquire
4-(1-Methyl-4-piperidinyl)-4H-benzo[4,5]cyclohepta[1,2-b]thi... Impurity CS-T-94089 4506-57-4 Enquire
4,4-Bis(2-ethylhexyl)-2,6-bis(trimethylstannyl)-4H-cyclopent... Impurity CS-O-39395 920504-00-3 Enquire
4-bromo-2-(trifluoromethyl)thiophene Impurity CS-DV-02632 1194374-08-7 Enquire
4-fluorobenzo[b]thiophene Impurity CS-DV-02788 310466-38-7 Enquire
5-(4-Fluorophenyl)-α-(5-iodo-2-methylphenyl)-2-thiophenemeth... Impurity CS-O-43987 1818268-45-9 Enquire
5-Chlorothiophene-2-carbaldehyde Impurity CS-AC-01407 7283-96-7 Enquire
6-methoxy-2-(4-methoxy-phenyl)-3-(3- trifluoromethylphenylsu... Impurity CS-O-38323 Not Available Enquire
6-Methoxy-2-(4-methoxyphenyl)benzo[b]thiophene Impurity CS-O-32256 63675-74-1 Enquire
Benzoylacetylthiophene BAT Impurity CS-O-50038 5912-44-7 Enquire
Ethyl-2-Amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carbox... Impurity CS-T-94137 174072-89-0 Enquire
Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate Impurity CS-T-33142 1094619-74-5 Enquire
Methyl 4-chloro-3-(chlorosulfonyl)thiophene-2-carboxylate Impurity CS-EO-03984 937639-93-5 Enquire
Methyl 4-chloro-3-(N-(2-methoxy-2-oxoethyl)sulfamoyl)thiophe... Impurity CS-EO-03985 937645-42-6 Enquire
N-thiophene-2-carboxylate Cefalotin Impurity CS-T-96115 104758-14-7 Enquire
rac Duloxetine 3-Thiophene Isomer Impurity CS-T-92262 116817-27-7 In Stock
Thiophene-2-carboxylic hydrazide Impurity CS-DL-00542 2361-27-5 Enquire


Intermediate

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2-(Ethylthio)thiophene Intermediate CS-O-51967 6911-35-9 Enquire
2,4,6-Trimethyldibenzothiophene Intermediate CS-ED-41979 185393-79-7 Enquire
2,4-Thiophenediethanol Intermediate CS-O-49803 Not Available Enquire
2-methyl benzothiophene Intermediate CS-ED-41980 1195-14-8 Enquire
3,4-Thiophenediethanol Intermediate CS-O-49800 1261445-71-9 Enquire
3-Methylamino-1-(thiophene-2-yl)propan-1-one Intermediate CS-O-45232 667465-15-8 In Stock
4-Bromo-benzo[b]thiophene Intermediate CS-CB-00001 5118-13-8 In Stock
6-Bromo-benzo[b]thiophene Intermediate CS-AC-07641 17347-32-9 In Stock
dimethyl 5-amino-4-cyanothiophene-2,3-dicarboxylate Intermediate CS-O-55424 99429-04-06 Enquire
Methyl 3-amino-4-methylthiophene-2-carboxylate Intermediate CS-O-32252 85006-31-1 In Stock
Methyl 3-Aminothiophene-2-carboxylate Intermediate CS-M-08730 22288-78-4 In Stock


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2-(1-hydroxy­lamino­ethyl­)-benz­othiophene Fine Chemicals CS-EU-00277 118564-89-9 Enquire
2-(2-Ethylhexyl)thiophene Fine Chemicals CS-ZG-96573 4891-44-5 Enquire
2-(2-hydroxyethyl)thiophene-3-carbaldehyde Fine Chemicals CS-O-39989 Not Available Enquire
2-(4-(Thien-2-yl)phenyl)thiophene Fine Chemicals CS-T-93983 23354-94-1 Enquire
2-(5-Bromo-2-fluorobenzyl)benzothiophene Fine Chemicals CS-N-05167 1034305-17-3 Enquire
2,3,4,5-Tetrakis(3',4'-dihydroxylphenyl)thiophene Fine Chemicals CS-EO-00138 1388814-41-2 Enquire
2,5-Dichlorothiophene Fine Chemicals CS-M-02569 3172-52-9 In Stock
2-Acetylthiophene Fine Chemicals CS-T-01196 88-15-3 Enquire
2-Amino-3-cyano-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene... Fine Chemicals CS-O-41054 1530793-63-5 Enquire
2-Amino-5-methylthiophene-3-carboxylic acid Fine Chemicals CS-EL-30829 41940-47-0 In Stock
2-bromo-3-(methylsulfanyl)thiophene Fine Chemicals CS-O-36962 94781-39-2 Enquire
2-Methylthiophene Fine Chemicals CS-M-01712 554-14-3 In Stock
3,4-dichlorothiophene-2-carboxylic acid Fine Chemicals CS-ZB-32149 61209-02-7 Enquire
3-Amino-4,5-dimethylthiophene-2-carboxylic acid Fine Chemicals CS-O-37394 98547-43-4 Enquire
3-Amino-5-(4-methoxyphenyl)thiophene-2-carboxamide Fine Chemicals CS-BL-00064 354812-16-1 Enquire
3-Aminothiophene-2-carbonitrile Fine Chemicals CS-MM-27181 56489-05-5 Enquire
3-bromo-2-fluorothiophene Fine Chemicals CS-O-38035 71176-17-5 Enquire
3-bromo-4-fluorothiophene Fine Chemicals CS-O-38034 133360-02-8 Enquire
3-Chloro-2-(chloromethyl)thiophene Fine Chemicals CS-BL-00142 112433-47-3 Enquire
3-Isocyanatothiophene Fine Chemicals CS-O-49546 76536-95-3 Enquire
3-Phenylthiophene Fine Chemicals CS-ED-42315 2404-87-7 Enquire
4,5 Dichloro 2-thiophene carbonyl chloride Fine Chemicals CS-O-34373 89283-13-6 Enquire
4-chloro-2-(chloromethyl)thiophene Fine Chemicals CS-O-37857 1305351-51-2 Enquire
4-Nitrophenyl 5-chlorothiophene-2-carboxylate Fine Chemicals CS-ZG-46341 1450877-56-1 Enquire
5-(tert-Butyl)benzo[b]thiophene Fine Chemicals CS-O-51643 17515-00-3 Enquire
5-Bromothiophene-2-carboxylic acid Fine Chemicals CS-M-01840 7311-63-9 Enquire
5-Chlorothiophene-2-carboxylic acid Fine Chemicals CS-O-31250 24065-33-6 In Stock
Benzo[1,2-b:6,5-b']dithiophene-4,5-diamine Fine Chemicals CS-ED-01939 1256138-44-9 Enquire
Benzo[2,1-b:3,4-b']dithiophene-4,5-dione Fine Chemicals CS-ED-01938 24243-32-1 Enquire
Benzothiophene Fine Chemicals CS-AC-10772 95-15-8 In Stock
Dibenzothiophene 5-Oxide Fine Chemicals CS-ED-26230 1013-23-6 In Stock
ethyl 2-amino-3-cyano-4-methyl-4,5,6,7-tetrahydrobenzo[b]thi... Fine Chemicals CS-O-41053 175599-84-5 Enquire
Ethyl 2-bromothiophene-3-carboxylate Fine Chemicals CS-ZH-04427 632325-50-9 Enquire
Ethyl 2-thiopheneacetate Fine Chemicals CS-O-56429 57382-97-5 Enquire
Methyl 5-chloro-3-(chlorosulfonyl)-2-thiophenecarboxylate Fine Chemicals CS-O-52125 126910-68-7 In Stock


Heterocyclic

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2-(Trifluoromethyl)thiophene Heterocyclic CS-EL-23917 86093-76-7 Enquire
4-Hydroxy-2-(trifluoromethyl)thiophene Heterocyclic CS-EL-27825 217959-45-0 Enquire
methyl 3-(3,5-dioxo-1,4-thiazinan-4-yl)-2-thiophenecarboxyla... Heterocyclic CS-EL-24549 338391-88-1 Enquire
Methyl 4-phenylthiophene-2-carboxylate Heterocyclic CS-EL-28422 21676-90-4 Enquire


Building Blocks

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(E)-N-(3-Methylaminopropyl)-2-thiopheneacrylamide Building Blocks CS-TB-99292 36700-39-7 Enquire
3,4,5-Tribromo-2-thiophenecarboxylic acid Building Blocks CS-O-52369 53317-05-08 Enquire
3-[[[[[[[(Acetylamino)carbonyl]amino]carbonyl]amino]carbonyl... Building Blocks CS-T-64539 171628-01-6 Enquire
5-chloro-3-(2,2-dibromoacetyl)thiophene-2-sulfonamide Building Blocks CS-O-44461 Not Available Enquire
5-Chloro-N-[(2S)-2,3-dihydroxypropyl]-2-thiophenecarboxamide Building Blocks CS-O-43712 721401-51-0 Enquire
Benzo[b]thiophene-2-boronic acid Building Blocks CS-M-01716 98437-23-1 Enquire
THIOPHENE-2,3-DIAMINE Building Blocks CS-O-48203 78648-62-1 Enquire


OLED

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
3-Bromo-5-phenylbenzo[b]thiophene OLED CS-O-57432 1638121-62-6 Enquire


Stable Isotope Reagent

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
4-bromodibenzo[b,d]thiophene-1,2,6,8,9-d5 Stable Isotope Reagent CS-O-48838 97511-05-2 (Unlabelled) Enquire
Tetrahydrothiophene- 2,2,5,5-d4 Stable Isotope Reagent CS-C-01687 31081-24-0 Enquire