Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Thyroxine, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Thyroxine impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Thyroxine-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Our Thyroxine-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Thyroxine Related Compounds
Stable Isotopes
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| [13C6]-L-Thyroxine sulfate | Stable Isotopes | CS-EK-00140 | 77074-49-8 unlabeled | Enquire |
| Levothyroxine- 13C6 | Stable Isotopes | CS-O-38573 | Not Available | Enquire |
| Levothyroxine- D5 | Stable Isotopes | CS-O-38575 | Not Available | Enquire |
| Levothyroxine-13C9-15N | Stable Isotopes | CS-O-03203 | 1431868-11-9 | Enquire |
| Levothyroxine-d3 | Stable Isotopes | CS-O-16186 | Not Available | In Stock |
| L-Thyroxine 13C9,15N | Stable Isotopes | CS-EK-01194 | 1435972-68-1 | Enquire |
| L-Thyroxine-[L-Tyr-d5] hydrochloride | Stable Isotopes | CS-I-00443 | 1261254-57-2 | Enquire |
| L-Thyroxine-[L-Tyr-d5] hydrochloride (Solution) | Stable Isotopes | CS-I-00554 | 1261254-57-2 | Enquire |
| L-Thyroxine-[L-Tyr-ring-13C6] hydrochloride (Solution) | Stable Isotopes | CS-I-00555 | 720710-30-5 | Enquire |
| N-Acetyl L-Thyroxine-13C6 | Stable Isotopes | CS-T-97054 | Not Available | Enquire |
| N-Acetyl L-Thyroxine-d3 | Stable Isotopes | CS-T-97053 | Not Available | Enquire |
| N-Formyl Thyroxine-13C6 | Stable Isotopes | CS-T-76633 | 1346604-89-4 | Enquire |
| Thyroxine Carboxy,a,ß,1,2,3,4,5,6-13C9,15N | Stable Isotopes | CS-T-86223 | 720710-31-6 | Enquire |
| Thyroxine d5 | Stable Isotopes | CS-O-11342 | 1322878-34-1 | Enquire |
| Thyroxine Glucuronide-13C6 Disodium Salt | Stable Isotopes | CS-T-102700 | 21462-56-6( Unlabelled) (free acid) | Enquire |
| Thyroxine Methyl Ester- 13C6 | Stable Isotopes | CS-T-99789 | Not Available | Enquire |
| Thyroxine-[L-Tyr-ring-13C6] hydrochloride | Stable Isotopes | CS-I-00424 | 720710-30-5 | Enquire |
| Thyroxine-13C6 | Stable Isotopes | CS-O-14503 | 1217780-14-7 | In Stock |
| β-Hydroxy Thyroxine-13C6 | Stable Isotopes | CS-T-96926 | Not Available | Enquire |
API Standards
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Dextrothyroxine Sodium | API Standards | CS-L-00144 | 137-53-1 | Enquire |
| D-Thyroxine | API Standards | CS-T-62056 | 51-49-0 | Enquire |
| Levothyroxine | API Standards | CS-BB-00023 | 51-48-9 | In Stock |
| Levothyroxine Sodium | API Standards | CS-O-01770 | 55-03-8 | In Stock |
| Levothyroxine Sodium Hydrate | API Standards | CS-O-16243 | 25416-65-3 | In Stock |
| Thyroxine Sodium | API Standards | CS-O-02455 | 55-03-8 | In Stock |
Metabolites
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Levothyroxine N-Methylamide | Metabolites | CS-O-14502 | 2088032-52-2 | In Stock |
| N-Acetyl L-Thyroxine Ethyl Ester | Metabolites | CS-T-01207 | 30804-52-5 | Enquire |
Impurities
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| *Levothyroxine | Impurities | CS-T-44338 | 32180-11-3 | In Stock |
| 3-Bromo-L-thyroxine | Impurities | CS-T-93287 | 1798894-90-2 | Enquire |
| Levothyroxine - Impurity G | Impurities | CS-O-39515 | Not Available | Enquire |
| levothyroxine Dimer | Impurities | CS-O-45712 | 2088032-62-4 | Enquire |
| Levothyroxine Dimer 2 | Impurities | CS-O-34272 | 1425050-65-2 (Racemic) | In Stock |
| Levothyroxine dimer-1 | Impurities | CS-O-34262 | 2086257-72-7 (Racemic) | In Stock |
| Levothyroxine EP Impurity B | Impurities | CS-O-15811 | 1628720-66-0 | In Stock |
| Levothyroxine EP Impurity C | Impurities | CS-T-45488 | 51-24-1 | In Stock |
| Levothyroxine EP Impurity D | Impurities | CS-T-43890 | 67-30-1 | In Stock |
| Levothyroxine EP Impurity E | Impurities | CS-T-19369 | 1041-01-6 | In Stock |
| Levothyroxine EP Impurity F | Impurities | CS-T-62058 | 911661-90-0 | In Stock |
| Levothyroxine EP Impurity G hydrochloride | Impurities | CS-O-33624 | 2230724-39-5 (Freebase) | In Stock |
| Levothyroxine EP Impurity H | Impurities | CS-T-43894 | 2055-97-2 | In Stock |
| Levothyroxine EP Impurity I | Impurities | CS-T-43892 | 2016-06-0 | In Stock |
| Levothyroxine EP Impurity K | Impurities | CS-O-14067 | 5817-39-0 | In Stock |
| Levothyroxine Ethyl Ester | Impurities | CS-T-44337 | 76353-71-4 | In Stock |
| Levothyroxine Impurity 30 Sodium Salt | Impurities | CS-P-08125 | Not Available | Enquire |
| Levothyroxine- Impurity 5 | Impurities | CS-DN-00016 | Not Available | Enquire |
| Levothyroxine Lactose Adduct | Impurities | CS-P-08082 | Not Available | In Stock |
| Levothyroxine Lactose Adduct (N-lactoside) | Impurities | CS-O-35442 | Not Available | Enquire |
| Levothyroxine Lactose Adduct (O-lactoside) | Impurities | CS-O-35443 | Not Available | Enquire |
| Levothyroxine Monochloro Impurity | Impurities | CS-O-16035 | 909279-46-5 | In Stock |
| Levothyroxine N- formamide Impurity | Impurities | CS-DN-00017 | Not Available | Enquire |
| Levothyroxine Related Compound 10 | Impurities | CS-P-08124 | 94345-95-6 | In Stock |
| Levothyroxine Sodium EP Impurity J | Impurities | CS-I-00089 | 70-40-6 | In Stock |
| Levothyroxine stearic acid impurity 1 | Impurities | CS-O-53552 | Not Available | Enquire |
| Levothyroxine stearic acid impurity 2 | Impurities | CS-O-53553 | Not Available | Enquire |
| Levothyroxine-4-Lactose Maillard Impurity | Impurities | CS-O-50307 | Not Available | Enquire |
| Levothyroxine-alpha-hydroxymethy-impurity | Impurities | CS-O-34260 | 2086257-60-3 | In Stock |
| O-(4-Hydroxy-3-iodophenyl) Levothyroxine | Impurities | CS-EO-03977 | Not Available | Enquire |
| Thyroxine Aminohexyl Ether Dihydrochloride | Impurities | CS-T-86816 | 1797130-15-4 | Enquire |
| Thyroxine Aminopropyl Ether | Impurities | CS-T-87342 | 1797884-40-2 | Enquire |
| Thyroxine sulfate | Impurities | CS-O-41678 | 77074-49-8 | Enquire |
EP Standards
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Levothyroxine for peak identification (Y0001382) | EP Standards | CS-EG-01445 | 25416-65-3 | Enquire |
Intermediates
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Boc-d-thyroxine | Intermediates | CS-ED-13996 | 89624-64-6 | Enquire |
| N-Acetyl L-Thyroxine | Intermediates | CS-T-01205 | 26041-51-0 | In Stock |
| N-Formyl Thyroxine | Intermediates | CS-T-24771 | 671235-41-9 | In Stock |
| Thyroxine 4'-O-Sulfate | Intermediates | CS-T-44340 | 77074-49-8 | Enquire |
| β-Hydroxy Thyroxine | Intermediates | CS-T-56505 | 107849-54-7 | Enquire |
Glucuronides
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Levothyroxine Mannitol Adduct | Glucuronides | CS-O-53867 | Not Available | Enquire |
| Thyroxine 4'-O-beta-D-Glucuronide | Glucuronides | CS-T-62059 | 21462-56-6 | Enquire |
| Thyroxine Acyl-beta-D-Glucuronide | Glucuronides | CS-T-62057 | 909880-81-5 | Enquire |
Building Blocks
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Fmoc-L-thyroxine | Building Blocks | CS-M-29819 | 151889-56-4 | Enquire |
| N-(tert-Butyloxy)carbonyl-L-thyroxine | Building Blocks | CS-T-09847 | 88404-22-2 | Enquire |
| N-(Trifluoroacetyl)-L-thyroxine Methyl Ester | Building Blocks | CS-T-62342 | 906325-95-9 | Enquire |