Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Thyroxine, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Thyroxine impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Thyroxine-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Our Thyroxine-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Thyroxine Related Compounds
Stable Isotopes
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Levothyroxine-d3 | Stable Isotopes | CS-O-16186 | Not Available | In Stock |
| L-Thyroxine-[L-Tyr-d5] hydrochloride | Stable Isotopes | CS-I-00443 | 1261254-57-2 | Enquire |
| L-Thyroxine-[L-Tyr-d5] hydrochloride (Solution) | Stable Isotopes | CS-I-00554 | 1261254-57-2 | Enquire |
| N-(Trifluoroacetyl)-thyroxine-13C6 4’-O-b-D-Glucuronide Tria... | Stable Isotopes | CS-T-98391 | Not Available | Enquire |
| N-Acetyl L-Thyroxine-13C6 | Stable Isotopes | CS-T-97054 | Not Available | Enquire |
| N-Acetyl L-Thyroxine-d3 | Stable Isotopes | CS-T-97053 | Not Available | Enquire |
| Thyroxine 13C12 | Stable Isotopes | CS-C-01512 | 1262750-40-2 | Enquire |
| Thyroxine Glucuronide-13C6 Disodium Salt | Stable Isotopes | CS-T-102700 | 21462-56-6( Unlabelled) (free acid) | Enquire |
| Thyroxine Methyl Ester- 13C6 | Stable Isotopes | CS-T-99789 | Not Available | Enquire |
| Thyroxine-13C6 | Stable Isotopes | CS-O-14503 | 1217780-14-7 | In Stock |
| β-Hydroxy Thyroxine-13C6 | Stable Isotopes | CS-T-96926 | Not Available | Enquire |
| Levothyroxine- 13C6 | Stable Isotopes | CS-O-38573 | Not Available | Enquire |
| Levothyroxine- D5 | Stable Isotopes | CS-O-38575 | Not Available | Enquire |
| Levothyroxine Sodium Hydrate | Stable Isotopes | CS-SS-25628-100MG | 25416-65-3 | Enquire |
| Levothyroxine-13C9-15N | Stable Isotopes | CS-O-03203 | 1431868-11-9 | Enquire |
| L-Thyroxine 13C9,15N | Stable Isotopes | CS-EK-01194 | 1435972-68-1 | Enquire |
| L-Thyroxine sulfate 13C6 | Stable Isotopes | CS-EK-00140 | 77074-49-8 unlabeled | Enquire |
| L-Thyroxine-[L-Tyr-ring-13C6] hydrochloride (Solution) | Stable Isotopes | CS-I-00555 | 720710-30-5 | Enquire |
| N-Formyl Thyroxine-13C6 | Stable Isotopes | CS-T-76633 | 1346604-89-4 | Enquire |
| Thyroxine Carboxy,a,ß,1,2,3,4,5,6-13C9,15N | Stable Isotopes | CS-T-86223 | 720710-31-6 | Enquire |
| Thyroxine d5 | Stable Isotopes | CS-O-11342 | 1322878-34-1 | Enquire |
| Thyroxine-[L-Tyr-ring-13C6] hydrochloride | Stable Isotopes | CS-I-00424 | 720710-30-5 | Enquire |
API
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Levothyroxine | API | CS-BB-00023 | 51-48-9 | In Stock |
| Levothyroxine Sodium | API | CS-O-01770 | 55-03-8 | In Stock |
| Levothyroxine Sodium Hydrate | API | CS-O-16243 | 25416-65-3 | In Stock |
| Thyroxine Sodium | API | CS-O-02455 | 55-03-8 | In Stock |
| Dextrothyroxine Sodium | API | CS-L-00144 | 137-53-1 | Enquire |
| D-Thyroxine | API | CS-T-62056 | 51-49-0 | Enquire |
Metabolite
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Levothyroxine N-Methylamide | Metabolite | CS-O-14502 | 2088032-52-2 | In Stock |
| N-Acetyl L-Thyroxine Ethyl Ester | Metabolite | CS-T-01207 | 30804-52-5 | Enquire |
Impurity
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| *Levothyroxine | Impurity | CS-T-44338 | 32180-11-3 | In Stock |
| levothyroxine Dimer | Impurity | CS-O-45712 | 2088032-62-4 | Enquire |
| Levothyroxine Dimer 2 | Impurity | CS-O-34272 | 1425050-65-2 (Racemic) | In Stock |
| Levothyroxine dimer-1 | Impurity | CS-O-34262 | 2086257-72-7 (Racemic) | In Stock |
| Levothyroxine EP Impurity B | Impurity | CS-O-15811 | 1628720-66-0 | In Stock |
| Levothyroxine EP Impurity C | Impurity | CS-T-45488 | 51-24-1 | In Stock |
| Levothyroxine EP Impurity D | Impurity | CS-T-43890 | 67-30-1 | In Stock |
| Levothyroxine EP Impurity E | Impurity | CS-T-19369 | 1041-01-6 | In Stock |
| Levothyroxine EP Impurity F | Impurity | CS-T-62058 | 911661-90-0 | In Stock |
| Levothyroxine EP Impurity G Hydrochloride | Impurity | CS-O-33624 | 2230724-39-5 (Freebase) | In Stock |
| Levothyroxine EP Impurity H | Impurity | CS-T-43894 | 2055-97-2 | In Stock |
| Levothyroxine EP Impurity I | Impurity | CS-T-43892 | 2016-06-0 | In Stock |
| Levothyroxine EP Impurity K | Impurity | CS-O-14067 | 5817-39-0 | In Stock |
| Levothyroxine Ethyl Ester | Impurity | CS-T-44337 | 76353-71-4 | In Stock |
| Levothyroxine Gallic acid adduct | Impurity | CS-O-54445 | ---- | Enquire |
| Levothyroxine Glucose Adduct | Impurity | CS-P-08177 | ---- | In Stock |
| Levothyroxine Lactose Adduct | Impurity | CS-P-08082 | Not Available | In Stock |
| Levothyroxine Lactose Adduct (N-lactoside) | Impurity | CS-O-35442 | Not Available | Enquire |
| Levothyroxine Monochloro Impurity | Impurity | CS-O-16035 | 909279-46-5 | In Stock |
| Levothyroxine Related Compound 10 | Impurity | CS-P-08124 | 94345-95-6 | In Stock |
| Levothyroxine Sodium EP Impurity J | Impurity | CS-I-00089 | 70-40-6 | In Stock |
| Levothyroxine stearic acid impurity 1 | Impurity | CS-O-53552 | ---- | Enquire |
| Levothyroxine stearic acid impurity 2 | Impurity | CS-O-53553 | ---- | Enquire |
| Levothyroxine-4-Lactose Maillard Impurity | Impurity | CS-O-50307 | Not Available | Enquire |
| Levothyroxine-alpha-hydroxymethy-impurity | Impurity | CS-O-34260 | 2086257-60-3 | In Stock |
| O-(4-Hydroxy-3-iodophenyl) Levothyroxine | Impurity | CS-EO-03977 | " 2086274-34-0" | Enquire |
| 3-Bromo-L-thyroxine | Impurity | CS-T-93287 | 1798894-90-2 | Enquire |
| Levothyroxine Impurity 30 Sodium Salt | Impurity | CS-P-08125 | Not Available | Enquire |
| Levothyroxine- Impurity 5 | Impurity | CS-DN-00016 | Not Available | Enquire |
| Levothyroxine- Impurity NMP | Impurity | CS-DN-00015 | Enquire | |
| Levothyroxine Lactose Adduct (O-lactoside) | Impurity | CS-O-35443 | Not Available | Enquire |
| Levothyroxine N- formamide Impurity | Impurity | CS-DN-00017 | Not Available | Enquire |
| Thyroxine Aminohexyl Ether Dihydrochloride | Impurity | CS-T-86816 | 1797130-15-4 | Enquire |
| Thyroxine Aminopropyl Ether | Impurity | CS-T-87342 | 1797884-40-2 | Enquire |
| Thyroxine sulfate | Impurity | CS-O-41678 | 77074-49-8 | Enquire |
| β-Hydroxy Thyroxine | Impurity | CS-T-56505 | 107849-54-7 | Enquire |
Intermediate
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| N-Acetyl L-Thyroxine | Intermediate | CS-T-01205 | 26041-51-0 | In Stock |
| N-Formyl Thyroxine | Intermediate | CS-T-24771 | 671235-41-9 | In Stock |
Glucuronide
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Levothyroxine Mannitol Adduct | Glucuronide | CS-O-53867 | ---- | Enquire |
| Thyroxine 4'-O-beta-D-Glucuronide | Glucuronide | CS-T-62059 | 21462-56-6 | Enquire |
| Thyroxine Acyl-beta-D-Glucuronide | Glucuronide | CS-T-62057 | 909880-81-5 | Enquire |
Fine Chemicals
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Levothyroxine disodium salt | Fine Chemicals | CS-O-34227 | 502481-31-4 | Enquire |
Secondary Standards
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Levothyroxine | Secondary Standards | CS-SS-24584-1GM | 51-48-9 | Enquire |
Building Blocks
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Fmoc-L-thyroxine | Building Blocks | CS-M-29819 | 151889-56-4 | Enquire |
| N-(tert-Butyloxy)carbonyl-L-thyroxine | Building Blocks | CS-T-09847 | 88404-22-2 | Enquire |
| N-(Trifluoroacetyl)-L-thyroxine Methyl Ester | Building Blocks | CS-T-62342 | 906325-95-9 | Enquire |