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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Trimethylsilyl, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Trimethylsilyl impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Trimethylsilyl-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Trimethylsilyl Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-[(tr... Stable Isotopes CS-T-100293 Not Available Enquire
(4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)a... Stable Isotopes CS-T-102535 Not Available Enquire
(4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)a... Stable Isotopes CS-T-100292 Not Available Enquire
1,2,3,4-Tetrahydro-5-methyl-2,4-bis[(trimethylsilyl)oxy]pyri... Stable Isotopes CS-T-99798 Not Available Enquire
11-O-Triethylsilyl-16-O-trimethylsilyl (8R,11R,12R,16RS)-Mis... Stable Isotopes CS-T-97129 Not Available Enquire
1-Pentyl-4-[2-(trimethylsilyl)ethynyl]benzene-d7 Stable Isotopes CS-T-102764 138220-08-3(Unlabelled) Enquire
2,4-Bis((trimethylsilyl)oxy)pyrimidine-13C,15N2 Stable Isotopes CS-T-100756 Not Available Enquire
2-Methyl-2-[(trimethylsilyl)oxy]propanenitrile-d6 Stable Isotopes CS-T-102537 107090-98-2 Enquire
3-(3-Pyridinylcarbonyl-D4)-1-(trimethylsilyl)-2-pyrrolidinon... Stable Isotopes CS-T-98761 Not Available Enquire
7,10-Bis[O-(triethylsilyl)]-10-deacetyl-13-O-trimethylsilyl ... Stable Isotopes CS-T-97749 Not Available Enquire
Calcitriol-dehydroxytrimethylsilyl-3,5-O-tert-butyldimethyls... Stable Isotopes CS-T-97721 Not Available Enquire
Trimethylsilyl 1-Oleo-2-linolein-d5 Stable Isotopes CS-T-102565 Not Available Enquire
1-(tert-Butyldimethylsilyloxy)-1-(2'-trimethylsilyl)ethynyl-... Stable Isotopes CS-T-50072 1246820-34-7 Enquire
2-Methyl-N-(4-nitro-3-trifluoromethylphenyl)-2-trimethylsily... Stable Isotopes CS-T-58515 223134-75-6 Enquire
rac-4-Methyl-4-[(trimethylsilyl)oxy]-1-octyne-d5 Stable Isotopes CS-T-82188 1189672-07-8 Enquire
Trimethylsilyl Cyanide-13C,15N Stable Isotopes CS-T-87749 81797-53-7 Enquire


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(2R)-3,4-Dihydro-5-[(4-nitrophenyl)methyl]-2-[(R)-phenyl[(tr... Impurity CS-O-52479 1818351-75-5 Enquire
(3R,4S,5R)-5-((S)-2,3-Bis((trimethylsilyl)oxy)propyl)-3,4-bi... Impurity CS-O-53676 ---- Enquire
(5α,11β)-11,21-Bis[(trimethylsilyl)oxy]pregnane-3,20-dione 3... Impurity CS-O-54331 57305-39-2 Enquire
(S)-3-((2R,5S)-5-(4-Fluorophenyl)-2-((S)-((4- fluorophenyl)a... Impurity CS-O-52481 Not Available Enquire
2,3,4,6-Tetra-O-(trimethylsilyl)-D-glucono-1,5-lactone Impurity CS-O-32367 32384-65-9 In Stock
3-ethoxy-17-hydroxy-11-methylen-17α-trimethylsilylethinyl-13... Impurity CS-O-43078 Not Available Enquire
4,4′-[(2S)-2-Pyrrolidinyl[(trimethylsilyl)oxy]methylene]bis[... Impurity CS-O-51910 1203648-36-5 Enquire
5-[1,2-bis(trimethylsilyloxy)ethyl]-3,4-bis(trimethylsilylox... Impurity CS-ED-42353 2348-31-4 Enquire
Eicos-11-Enyl Trimethylsilyl Fumarate Impurity CS-O-57257 ---- Enquire
Ezetimibe O-trimethylsilyl O-benzyl Impurity Impurity CS-O-47150 1197343-09-1 Enquire
Heptadecyl Trimethylsilyl Fumarate Impurity CS-O-57256 ---- Enquire
N-trimethylsilyl-Ritalinic acid trimethylsilyl ester Impurity CS-O-47884 Not Available Enquire
Ruxolitinib-7-(((2-(trimethylsilyl)ethoxy)methoxy)methyl)-im... Impurity CS-O-56930 ---- Enquire
(4-benzyl-3-((trimethylsilyl)ethynyl)-3,4-dihydro-2H-benzo[b... Impurity CS-EM-03607 1799616-60-6 Enquire
(Isocyanomethyl)trimethyl-silane; (Trimethylsilyl)methyl iso... Impurity CS-DV-00259 30718-17-3 Enquire
1-(Trimethylsilyl)-1-propyn-3-yl Tosylate Impurity CS-T-32688 71321-16-9 Enquire
1-(Trimethylsilyl)propyne Impurity CS-T-45734 6224-91-5 Enquire
1,1,1-trimethyl-N-((S)-2-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-tr... Impurity CS-O-40046 1135491-84-7 Enquire
1,1-Dimethyl-2-trimethylsilyloxyethylamine Impurity CS-T-53706 38421-19-1 Enquire
1-[[2-(Trimethylsilyl)ethoxy]methyl]-1H-pyrrolo[2,3-b]pyridi... Impurity CS-DJ-00912 879132-48-6 Enquire
1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[2,3-b]pyridi... Impurity CS-EM-01671 879132-46-4 Enquire
1’,2,3,4-Tetra-O-trimethylsilylepilincomycin Impurity CS-T-87048 25405-72-5 Enquire
17-O-Trimethylsilyl 6,7-Dehydro Norethindrone Impurity CS-T-62492 300542-58-9 Enquire
17-O-Trimethylsilyl Norethindrone Impurity CS-T-62495 28426-43-9 Enquire
2-(Bis(trimethylsilyl)amino)methyl-4,4,5,5-tetramethyl-1,3,2... Impurity CS-O-53824 191400-35-8 Enquire
2,3,4-Tri-O-trimethylsilyllincomycin Impurity CS-T-87949 25420-97-7 Enquire
2,3,4-Tris-O-(trimethylsilyl) 7-Epi Clindamycin Impurity CS-T-62555 25399-48-8 Enquire
2-Debenzoyl-7,10-bis[O-(triethylsilyl)]-10-deacetyl-13-O-tri... Impurity CS-T-51657 159383-94-5 Enquire
3-Methyl-6-((trimethylsilyl)ethynyl)-3H-imidazo-[4,5-b]pyrid... Impurity CS-M-24026 1138444-16-2 Enquire
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-([2-(trime... Impurity CS-DL-00635 894807-98-8 Enquire
4-Chloro-2-(trimethylsilyl)phenyl trifluoromethanesulfonate Impurity CS-ZH-13415 262373-16-0 Enquire
4-Chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3... Impurity CS-M-24043 941685-26-3 Enquire
4-cyano-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazole-2-... Impurity CS-DV-02759 854123-78-7 Enquire
4-Methyl-7-trimethylsilyloxycoumarin Impurity CS-T-35282 67909-31-3 Enquire
7,10-Bis[O-(triethylsilyl)]-10-deacetyl-13-O-trimethylsilyl ... Impurity CS-T-49439 159383-93-4 Enquire
Bis(trimethylsilyl)-5-azacytosine Impurity CS-O-41047 52523-35-0 Enquire
D-(-)-Norgestrel Trimethylsilyl Ether Impurity CS-T-59732 39942-01-3 Enquire
Methyl 3-(trimethylsilyl)-4-pentenoate Impurity CS-P-07820 185411-12-5 Enquire
N-(Methoxymethyl)-2-methyl-N-[(trimethylsilyl)-methyl]-2-pro... Impurity CS-M-53362 455954-96-8 Enquire
N-(Trimethylsilyl)-4-[(trimethylsilyl)oxy]-1,3,5-triazin-2-a... Impurity CS-O-39480 52523-35-0 Enquire
N,N-Bis(trimethylsilyl)-(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a... Impurity CS-O-37985 514820-48-5 Enquire
N,N-Diethyl(trimethylsilyl)amine Impurity CS-T-52831 996-50-9 Enquire
tert-Butyl 2-iodo-6-((trimethylsilyl)ethynyl)-pyridin-3-yl c... Impurity CS-M-24228 1142192-40-2 Enquire
tert-Butyl 5-methoxy-4-(trimethylsilyl)pyridin-3-ylcarbamate Impurity CS-M-23936 1045858-18-1 Enquire
TRIBUTYL(TRIMETHYLSILYL)STANNANE Impurity CS-DL-00674 17955-46-3 Enquire


Intermediate

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2-(Trimethylsilyl)ethoxymethyl Chloride Intermediate CS-T-62344 76513-69-4 In Stock
2-Trimethylsilylethanol Intermediate CS-M-14553 2916-68-9 In Stock
7-(trimethylsilyl)-2,6-bis((trimethylsilyl)oxy)-7H-purine Intermediate CS-O-48856 18641-05-9 In Stock
N,O-Bis(trimethylsilyl)acetamide Intermediate CS-O-10667 10416-59-8 In Stock
Trimethylsilyl Cyanide Intermediate CS-T-45717 7677-24-9 In Stock


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
1-(Trimethylsilyl)imidazole Fine Chemicals CS-M-01798 18156-74-6 In Stock
1-[2-(Trimethylsilyl)Ethoxycarbonyloxy]Pyrrolidin-2,5-Dione Fine Chemicals CS-DV-00791 78269-85-9 In Stock
3R,4S,5R)-5-((R)-2,2,7,7-tetramethyl-3,6-dioxa-2,7-disilaoct... Fine Chemicals CS-O-54872 55515-33-8 Enquire
N,N-Bis-(Trimethylsilyl)-urea Fine Chemicals CS-O-03551 18297-63-7 In Stock
N,O-Bis(trimethylsilyl)trifluoroacetamide Fine Chemicals CS-T-07309 25561-30-2 In Stock
Sodium bis(trimethylsilyl)amide Fine Chemicals CS-O-10520 1070-89-9 Enquire
Trimethylsilyl acetate Fine Chemicals CO-K-00035 2754-27-0 In Stock
Trimethylsilyl diazomethane 2.0M in Hexanes Fine Chemicals CS-DA-00608-100ML 18107-18-1 In Stock
(3R,4S,5R,6R)-3,4,5-Tris((trimethylsilyl)oxy)-6-(((trimethyl... Fine Chemicals CS-O-36899 32469-28-6 Enquire
(S)-Trimethylsilyl-3-phenyl-2((trimethylsilyl)amino)propanoa... Fine Chemicals CS-ED-01043 7364-51-4 Enquire
1-((8-oxo-7-((trimethylsilyl)amino)-2-(((trimethylsilyl)oxy)... Fine Chemicals CS-O-35746 98445-42-2 Enquire
1,2-Bis(trimethylsilyloxy)ethane Fine Chemicals CS-DA-00055 7381-30-8 Enquire
2,4-Dichloro-7-((2-(trimethylsilyl)ethoxy)-methyl)-7H-pyrrol... Fine Chemicals CS-MM-27966 442847-52-1 Enquire
2-[(Trimethylsilyl)ethynyl]pyridine Fine Chemicals CS-DJ-00779 86521-05-3 Enquire
3-(Trimethylsilyl)propiolic acid Fine Chemicals CS-MM-12209 5683-31-8 Enquire
3,3-Dibromo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[... Fine Chemicals CS-MM-11805 879132-47-5 Enquire
3,3-Dimethyl-1-(trimethylsilyl)-1-butyne Fine Chemicals CS-MM-06323 14630-42-3 Enquire
4-Nitrophenyl 2-(Trimethylsilyl)ethyl Carbonate Fine Chemicals CS-DE-01462 80149-80-0 Enquire
6-O-Methyl-2,4-bis-O-(trimethylsilyl)erythromycin9-[O-(1-eth... Fine Chemicals CS-MM-00248 119699-81-9 Enquire
Acetaldehyde, 2-[(trimethylsilyl)oxy]- Fine Chemicals CS-O-38556 Not Available Enquire
Mono-(trimethylsilyl)-phosphite Fine Chemicals CS-H-00496 91076-68-5 Enquire
N-methyl (trimethylsilyl)-N-((trimethylsilyl) methyl) methan... Fine Chemicals CS-O-37264 69320-67-8 Enquire
N-methyl-1-(trimethylsilyl)methanamine Fine Chemicals CS-ED-01038 18135-05-2 Enquire
Potassium bis(trimethylsilyl)amide Fine Chemicals CS-O-10521 40949-94-8 Enquire
Sodium bis(trimethylsilyl)amide, 1M in THF Fine Chemicals CS-BX-02607 1070-89-9 Enquire
Sodium bis(trimethylsilyl)amide, 2M in THF Fine Chemicals CS-BX-02608 1070-89-9 Enquire
tert-Butyl (Trimethylsilyl)acetate Fine Chemicals CS-T-09885 41108-81-0 Enquire
Trimethyl-(methyl-triacontyl-trimethylsilyloxysilyl)oxysilan... Fine Chemicals CS-ZH-21920 401514-97-4 Enquire
trimethylsilyl 3-(acetoxymethyl)-8-oxo-7-((trimethylsilyl)am... Fine Chemicals CS-O-35745 31461-04-8 Enquire


Nitrosamine

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
1,1,1-trimethyl-N-nitroso-N-(trimethylsilyl)Silanamine Nitrosamine CS-O-36909 1233340-47-0 Enquire


Polymers

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
mC1(poly(1-phenyl-2-(m-(trimethylsilyl)phenyl)acetylene) Polymers CS-O-48169 Not Available Enquire
pC1(poly(1-phenyl-2-(p-(trimethylsilyl)phenyl)acetylene) Polymers CS-O-48168 Not Available Enquire
Poly(1-trimethylsilyl-1-propyne) Polymers CS-PM-00187 Not Available Enquire
Poly(4-[N,N-di(trimethylsilyl)-aminomethyl]-styrene) Polymers CS-PM-00161 Not Available Enquire
Poly(styrene)-b-poly(4-[N,N-bis(trimethylsilyl)-aminomethyl]... Polymers CS-PM-00310 Not Available Enquire
Poly(styrene)-b-poly(dimethylsiloxane), w-trimethylsilyl-ter... Polymers CS-PM-00360 Not Available Enquire


Reagents

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Lithium bis(trimethylsilyl)amide 1.0 M in THF Reagents CS-BX-02469-100ML 4039-32-1 Enquire
Lithium bis(trimethylsilyl)amide 1.0 M in THF Reagents CS-BX-02469-1 Ltr 4039-32-1 Enquire


Solvent

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Potassium bistrimethylsilylamide 1.0 M in THF Solvent CS-O-49743 40949-94-8 In Stock


Stable Isotope Reagent

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
3-(Trimethylsilyl)-1-propane-1,1,2,2,3,3-d6-sulfonic Acid So... Stable Isotope Reagent CS-T-62497 284664-85-3 Enquire
N-Methyl-N-(trimethylsilyl)trifluoroacetamide-d9 Stable Isotope Reagent CS-T-58712 945623-67-6 Enquire


Building Blocks

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2,7-Bis(trimethylsilyl)-4,5-pyrenedione Building Blocks CS-O-48201 Not Available Enquire
3-Methoxy-2-(trimethylsilyl)phenyl trifluoromethanesulfonate Building Blocks CS-O-44698 217813-03-1 Enquire
Methyl (trimethylsilyl)propiolate Building Blocks CS-ED-41538 42201-71-8 Enquire
(3-Trimethylsilyl-2-propynyl)triphenylphosphonium Bromide Building Blocks CS-T-45736 42134-49-6 Enquire
(4-Trimethylsilyl ethynyl)phenyl-1-phenylethylene Building Blocks CS-PM-01729 2247621-55-0 Enquire
(Trimethylsilyl)methylmagnesium chloride Building Blocks CS-O-10510 13170-43-9 Enquire
2-(Trimethylsilyloxy)ethyl methacrylate Building Blocks CS-PM-01725 17407-09-9 Enquire
3-Trimethylsilylphenylboronic acid Building Blocks CS-M-53363 177171-16-3 Enquire
4-Trimethylsilylphenylboronic acid Building Blocks CS-M-53364 17865-11-1 Enquire
Trimethylsilyl trifluoroacetate Building Blocks CS-M-02851 400-53-3 Enquire
Trimethylsilyl undec-10-enoate Building Blocks CS-PM-01732 24338-09-8 Enquire


Carbohydrates

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
1,2,3,4,6-Pentakis-O-(trimethylsilyl) a-D-Galactose Carbohydrates CS-T-60253 32166-80-6 Enquire
1,2,3,4,6-Penta-trimethylsilyl Glucopyranose Carbohydrates CS-T-38986 19126-99-9 Enquire


Deuterated Reagents

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
3-(Trimethylsilyl)propionic Acid-d4 Sodium Salt Deuterated Reagents CS-T-62496 24493-21-8 In Stock