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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Upadacitinib, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Upadacitinib impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Upadacitinib-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Upadacitinib Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Upadacitinib D2 Stable Isotopes CS-O-41436 2768445-46-9 Enquire
Upadacitinib-D2,15N Stable Isotopes CS-T-103804 1310726-60-3(unlabelled) Enquire
Upadacitinib-d4 (major) Stable Isotopes CS-F-00244 1310726-60-3 (unlabelled) Enquire


API

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Upadacitinib API CS-T-87522 1310726-60-3 Enquire
Upadacitinib Hydrate API CS-ED-41494 2050057-56-0 Enquire


Metabolite

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Upadacitinib M11 Metabolite Metabolite CS-O-40189 Not Available Enquire


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(3R,4R)-3-Bromoacetyl-4-ethyl-N-(2,2,2-trifluoroethyl) pyrro... Impurity CS-O-58522 ---- Enquire
(3R,4S)-3-Acetyl-4-ethyl-N-(2,2,2-trifluoro ethyl)pyrrolidin... Impurity CS-O-58517 2576426-11-2 Enquire
(3R,4S)-3-Chloroacetyl-4-ethyl-N-(2,2,2-trifluoroethyl) pyrr... Impurity CS-O-58526 ---- Enquire
(3R,4S)-3-Dibromoacetyl-4-ethyl-N-(2,2,2-trifluoroethyl) pyr... Impurity CS-O-58520 ---- Enquire
(3S,4R)-3-Bromoacetyl-4-ethyl-N-(2,2,2-trifluoroethyl) pyrro... Impurity CS-O-58524 ---- Enquire
(3S,4S)-3-Bromoacetyl-4-ethyl-N-(2,2,2-trifluoroethyl) pyrro... Impurity CS-O-58523 ---- Enquire
3-Tosyl Upadacitinib impurity Impurity CS-O-45305 1428243-28-0 Enquire
Benzyl (3R,​4S)​-​3-​(2-​bromoacetyl)​-​4-​ethylpyrrolidine-... Impurity CS-O-44407 1428243-26-8 Enquire
N1-Methyl Upadacitinib impurity Impurity CS-O-45306 Not Available Enquire
N-Des-(2,2,2-trifluoroethyl) Upadacitinib Impurity CS-O-45302 Not Available Enquire
N-Methyl Upadacitinib Impurity CS-O-45308 Not Available Enquire
Tert-Butyl (5-tosyl-5H-[2,5'-bipyrrolo[2,3-b]pyrazin]-2'-yl)... Impurity CS-O-58527 ---- Enquire
Upadacitinib 1-carboxamide Impurity Impurity CS-O-58935 ---- Enquire
Upadacitinib 3-Hydroxy 4-N-oxide Impurity Impurity CS-O-58937 ---- Enquire
Upadacitinib 3-Hydroxy 6-N-oxide Impurity Impurity CS-O-58938 ---- Enquire
Upadacitinib 3-Hydroxy Impurity Impurity CS-O-58936 ---- Enquire
Upadacitinib 6-N-Oxide Impurity Impurity CS-O-58934 ---- Enquire
Upadacitinib Cyclized impurity Impurity CS-O-45312 1708997-42-5 Enquire
Upadacitinib Des tosyl impurity Impurity CS-O-45313 1708997-43-6 Enquire
Upadacitinib Di tosyl impurity Impurity CS-O-45311 Not Available Enquire
Upadacitinib di-formamyl Impurity Impurity CS-O-58939 ---- Enquire
Upadacitinib Impurity 11 Impurity CS-O-58512 ---- Enquire
Upadacitinib Impurity 12 Impurity CS-O-58514 ---- Enquire
Upadacitinib Impurity 14 Impurity CS-EO-02331 2715120-86-6 Enquire
Upadacitinib Impurity 3 Impurity CS-EO-01270 1310726-59-0 In Stock
Upadacitinib Impurity 34 Impurity CS-O-58516 ---- Enquire
Upadacitinib Impurity 35 Impurity CS-P-09216 ---- Enquire
Upadacitinib Impurity 4 Impurity CS-EO-01271 ---- Enquire
Upadacitinib Impurity 5 Impurity CS-EO-01272 ---- Enquire
Upadacitinib N-Formamyl Impurity Impurity CS-O-58940 ---- Enquire
Upadacitinib TFEA Carbamate impurity Impurity CS-O-45309 2411540-30-0 In Stock
Upadacitinib Trifluoroacetamide impurity Impurity CS-O-45310 2768445-19-6 Enquire
Upadacitinib Impurity 8 Impurity CS-EO-02054 2460133-49-5 Enquire


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
3-Bromo-5H-pyrrolo[2,3-b]pyrazine Fine Chemicals CS-MM-43762 1260665-49-3 Enquire


Nitrosamine

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
N- Nitroso Upadacitinib (Possibility 2) Nitrosamine CS-O-59951 ---- Enquire
N-Nitroso Upadacitinib Nitrosamine CS-O-46129 ---- Enquire
Upadacitinib Nitroso Impurity 4 Nitrosamine CS-O-59952 ---- Enquire