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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Varenicline, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Varenicline impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Varenicline-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Varenicline Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
N-Nitroso Varenicline 15N d2 Stable Isotopes CS-O-49260 Not Available Enquire
N-Nitroso Varenicline Impurity 17-d4 Stable Isotopes CS-O-59610 Not Available In Stock
N-Nitroso Varenicline-15N Stable Isotopes CS-O-39982 Not Available In Stock
N-nitrosovarenicline-d12 Stable Isotopes CS-O-40725 Not Available Enquire
Varenicline 13C15N Stable Isotopes CS-O-00654 249296-44-4 Enquire
Varenicline Carbamoyl β-D-Glucuronide-d4 Stable Isotopes CS-T-101972 Not Available Enquire
Varenicline Nitroso D2 Stable Isotopes CS-EO-02978 Not Available Enquire
Varenicline Nitroso D4 Stable Isotopes CS-EO-02977 Not Available Enquire
Varenicline-d2,15N2 Dihydrochloride Stable Isotopes CS-T-101971 Not Available Enquire
Varenicline-d4 Dihydrochloride (Major) Stable Isotopes CS-T-93439 866823-63-4 (Unlabeled) Enquire
Varenicline 13C2 15N2 Stable Isotopes CS-O-31047 2140265-12-7 Enquire
Varenicline D4 Stable Isotopes CS-P-08216 2183239-01-0 Enquire
Varenicline-d4 Hydrochloride (Major) Stable Isotopes CS-T-93710 1185326-06-0 (Unlabeled) Enquire


API

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Varenicline API CS-O-14487 249296-44-4 In Stock
Varenicline citrate API CS-ED-41542 536696-70-5 Enquire
Varenicline Tartrate API CS-O-31032 375815-87-5 In Stock


Metabolite

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
N-Formyl Varenicline Metabolite CS-O-05919 796865-82-2 In Stock


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(1S,5R)-Varenicline Impurity 14 Impurity CS-O-59351 ---- Enquire
(6R,10R)-8-oxido-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[... Impurity CS-O-57212 ---- Enquire
(6R,10S)-Varenicline Impurity 20 Impurity CS-O-59349 ---- Enquire
(6R,10S)-Varenicline Impurity 36 Impurity CS-O-59354 ---- Enquire
(6R,10S)-Varenicline Impurity 37 Impurity CS-O-59356 ---- Enquire
(6R,10S)-Varenicline N-Oxide Impurity CS-O-37887 ---- Enquire
2,2,2-trifluoro-1-(1,2,4,5-tetrahydro-6,8-dinitro-1,5-methan... Impurity CS-O-16039 853946-18-6 In Stock
2,3,4,5-Tetrahydro-1,5- methano-1H-3-benzazepine- 7,8-diamin... Impurity CS-O-33143 950781-89-2 In Stock
2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benz... Impurity CS-T-43875 230615-69-7 Enquire
2,3,4,5-Tetrahydro-7,8- dinitro-1,5-methano-1H-3- benzazepin... Impurity CS-O-33142 230615-08-4 In Stock
4-Nitrobenzoyl Varenicline Impurity CS-T-83249 1329651-19-5 In Stock
Methyl Varenicline Impurity CS-T-82149 1333145-89-3 Enquire
N-Acetyl Varenicline Impurity CS-O-33509 1213781-59-9 In Stock
Varenicline 1-N-oxide Impurity CS-O-44780 2306217-12-7 In Stock
Varenicline Impurity 1 Impurity CS-O-14514 230615-53-9 In Stock
Varenicline Impurity 13 Hydrochloride Impurity CS-P-08621 1350219-74-7 Enquire
Varenicline Impurity 15 Impurity CS-EO-00932 2803960-64-5 In Stock
Varenicline Impurity 17 Impurity CS-EO-00931 Not Available In Stock
Varenicline Impurity 18 Impurity CS-EO-01913 2306217-15-0 In Stock
Varenicline Impurity 19 Impurity CS-O-59346 ---- Enquire
Varenicline Impurity 3 Impurity CS-O-33141 357424-12-5 Enquire
Varenicline Impurity 3 Dihydrocloride Impurity CS-O-14516 ---- Enquire
Varenicline Impurity 39 Impurity CS-EO-02156 Not Available Enquire
Varenicline Impurity 48 Impurity CS-EO-02272 Not Available Enquire
Varenicline Impurity 49 Impurity CS-EO-02271 Not Available Enquire
Varenicline Maleate Adduct Impurity CS-O-57891 2272868-54-7 Enquire
Varenicline Maltotriose impurity Impurity CS-O-48444 Not Available Enquire
Varenicline N-dioxide HCl Impurity CS-O-44860 Not Available In Stock
Varenicline N-Methyl Impurity Impurity CS-DN-00037 328055-92-1 In Stock
Varenicline N-Oxide Impurity CS-O-14513 ---- In Stock
Varenicline Tartrate Impurity C Impurity CS-O-35347 2724982-86-7 In Stock
Varenicline Tartrate Impurity-II Impurity CS-O-43821 Not Available Enquire
2,2,2-trifluoro-1-(5,6,8,9-tetrahydro-5,9-ethanoimidazo[4,5-... Impurity CS-O-34824 832089-32-4 Enquire
2,3,4,5-Tetrahydro-1,5-methano-1H-3-benzazepine-7,9-diamine Impurity CS-O-33139 950781-91-6 Enquire
2,3,4,5-Tetrahydro-1,5-methano-1H-3-benzazepine-7-amine Impurity CS-O-33137 357424-22-7 Enquire
2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benz... Impurity CS-O-33136 230615-56-2 Enquire
3-(Trifluoroacetyl)-8-nitro-2,3,4,5-Tetrahydro-1,5-methano-1... Impurity CS-O-33140 950781-89-2 Enquire
3-hydroxy-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]q... Impurity CS-O-36015 2306217-11-6 Enquire
4,5-dihydro-1H-1,5-methanobenzo[d]azepine-3,7,8(2H)-triamine Impurity CS-O-36136 Not Available Enquire
4,6,7,8,9,10-hexahydro-1H-6,10-methano-pyrazino[2,3-h][3]ben... Impurity CS-O-33133 357424-07-8 Enquire
7,8,9,10-Tetrahydro-6,10-Methano-6H-pyrazino[2,3-h][3]benzaz... Impurity CS-T-61849 1337563-47-9 Enquire
bis(6,7,9,10-tetrahydro-8H-6,10-methanoazepino[4,5-g]quinoxa... Impurity CS-O-34823 Not Available Enquire
Varenicline Impurity Impurity CS-O-34534 Not Available Enquire
Varenicline Impurity (Hydroxymethyl) Impurity CS-O-41063 Not Available Enquire
Varenicline Impurity 2 Impurity CS-O-14515 357426-10-9 Enquire
Varenicline Impurity 25 Impurity CS-EO-01089 Not Available Enquire
VARENICLINE IMPURITY 35 Impurity CS-O-41100 2306217-13-8 Enquire
VARENICLINE IMPURITY 36 Impurity CS-O-41101 2306217-14-9 Enquire
Varenicline Impurity 38 Impurity CS-EO-01924 2759288-58-7 Enquire
Varenicline Impurity 4 Impurity CS-O-14517 357424-21-6 Enquire
Varenicline Impurity 5 Impurity CS-O-14518 950781-87-0 Enquire
Varenicline Impurity 6 Impurity CS-O-14519 1026685-55-1 Enquire
Varenicline impurity, N-Hydroxy Impurity CS-DN-00032 Not Available Enquire
Varenicline Metadiamino HCl impurity Impurity CS-DN-00038 Not Available Enquire
Varenicline Metadinitro Impurity CS-O-14512 853946-18-6 Enquire
Varenicline Metadinitro Impurity Impurity CS-DN-00034 Not Available Enquire
Varenicline Monoamino Impurity Impurity CS-DN-00036 Not Available Enquire
Varenicline Mononitro Impurity/Impurity Impurity CS-DN-00035 Not Available Enquire
Varenicline N-dioxide Impurity CS-O-34679 Not Available Enquire


Intermediate

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benz... Intermediate CS-O-10563 230615-51-7 In Stock
N-trifluoroacetyl Varenicline Intermediate CS-MM-12524 230615-70-0 In Stock


Glucuronide

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Varenicline Carbamoyl-O-Beta-D-glucuronide Glucuronide CS-O-05713 535920-98-0 In Stock


Nitrosamine

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Depyrazine 6,8-Dinitro-3-nitroso Varenicline Nitrosamine CS-O-44468 Not Available Enquire
Mono Nitroso Varenicline impurity Nitrosamine CS-O-46079 Not Available In Stock
N-nitroso Depyrazine 7,8-Dinitrophenyl Varenicline Nitrosamine CS-O-36135 2803960-63-4 In Stock
N-Nitroso Varenicline Nitrosamine CS-O-36107 2755871-02-2 In Stock
N-Nitroso Varenicline 1,4-Di-N-Oxide Nitrosamine CS-O-58684 ---- Enquire
N-Nitroso Varenicline N-Oxide Nitrosamine CS-O-58683 Not Available In Stock
Varenicline Nitroso Impurity 6 Nitrosamine CS-EO-01923 Not Available Enquire


Stable Isotope Reagent

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
N-nitroso-varenicline 200μg/mL in Methanol Stable Isotope Reagent CS-O-40723 Not Available Enquire
N-nitrosovarenicline-d12 200μg/mL in Methanol Stable Isotope Reagent CS-O-40724 Not Available Enquire


Analytical Standard

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
N-nitroso-varenicline-100 PPM in Acetonitrile Analytical Standard CS-O-36107-1.5ML 2755871-02-2 Enquire
Varenicline Impurity 9(N-Nitroso varenicline) Analytical Standard CS-O-36107-10MG 2755871-02-2 Enquire