Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Ibuprofen, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Ibuprofen impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Ibuprofen-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Our Ibuprofen-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Ibuprofen Related Compounds
Stable Isotopes
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (±)-Ibuprofen-d4 (propionic -2,3,3,3-d4) | Stable Isotopes | CS-C-01412 | 15687-27-1(unlabelled) | Enquire |
| (R)-Ibuprofen-d3 | Stable Isotopes | CS-O-10054 | 121702-86-1 | In Stock |
| Dexibuprofen-d3 | Stable Isotopes | CS-O-02887 | 1329643-44-8 | Enquire |
| Hydroxy Ibuprofen-d3 | Stable Isotopes | CS-T-101299 | Not Available | Enquire |
| Ibuprofen 13C,d3 | Stable Isotopes | CS-T-92581 | 1261394-40-4 | In Stock |
| Ibuprofen-d3 | Stable Isotopes | CS-O-10055 | 121662-14-4 | In Stock |
| Ibuprofen-d3 Acyl-β-D-glucuronide (mixture of diastereomers) | Stable Isotopes | CS-T-98445 | Not Available | Enquire |
| Ibuprofen-d3 Alcohol | Stable Isotopes | CS-T-101239 | 1794979-83-1 | Enquire |
| Ibuprofen-d4 | Stable Isotopes | CS-O-42920 | 103974-30-7 | Enquire |
| p-Butyl Ibuprofen-d3 Sodium Salt | Stable Isotopes | CS-T-100964 | Not Available | Enquire |
| rac 2-(tert-Butyldimethylsilyloxy) Ibuprofen-d6 | Stable Isotopes | CS-T-101754 | Not Available | Enquire |
| rac 2-(tert-Butyldimethylsilyloxy)-a-desmethyl Ibuprofen-d6 | Stable Isotopes | CS-T-101752 | Not Available | Enquire |
| rac 2-(tert-Butyldimethylsilyloxy)-a-desmethyl Ibuprofen-d6 ... | Stable Isotopes | CS-T-101753 | Not Available | Enquire |
| rac-Ibuprofen-13C3 | Stable Isotopes | CS-T-103701 | 15687-27-1(unlabelled) | Enquire |
| (+/-)-Ibuprofen-d3, Sodium Salt (a-methyl-d3) | Stable Isotopes | CS-C-00888 | 1219805-09-0 | Enquire |
| [U-Ring-13C6]-Ibuprofen | Stable Isotopes | CS-EK-00857 | 1216459-54-9 | Enquire |
| Ibuprofen Carboxylic Acid-d3 | Stable Isotopes | CS-T-56569 | 1216505-29-1 | Enquire |
| m-Isobutyl Ibuprofen-d3 | Stable Isotopes | CS-O-40123 | 1346598-90-0 | Enquire |
| rac 2-Hydroxy Ibuprofen-d6 | Stable Isotopes | CS-T-56077 | 1217055-71-4 | Enquire |
API
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Ibufenac | API | CS-T-29039 | 1553-60-2 | In Stock |
| Ibuprofen | API | CS-O-01647 | 15687-27-1 | In Stock |
| Ibuprofen Lysinate | API | CS-EL-00119 | 57469-77-9 | In Stock |
| Ibuprofen Sodium | API | CS-O-06340 | 31121-93-4 | In Stock |
Metabolite
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| 1-Hydroxyibuprofen | Metabolite | CS-W-00212 | 53949-53-4 | In Stock |
| 2-Hydroxyibuprofen | Metabolite | CS-W-00202 | 51146-55-5 | In Stock |
| 3-Hydroxyibuprofen | Metabolite | CS-W-00209 | Not Available | Enquire |
| Carboxyibuprofen | Metabolite | CS-W-00203 | Not Available | Enquire |
Impurity
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (R)-2-(4-Butylphenyl)propanoic Acid | Impurity | CS-O-56781 | 1263078-21-2 | Enquire |
| (R)-Ibuprofen | Impurity | CS-O-07857 | 51146-57-7 | In Stock |
| (R,R)-N-(1-Phenylethyl) Ibuprofen Amide | Impurity | CS-T-60425 | 121734-80-3 | In Stock |
| (S)-(+)-Ibuprofen Propylene Glycol Ester | Impurity | CS-EO-01027 | 95093-58-6 | In Stock |
| (S)-3-methyl-2-phenylbutanamide | Impurity | CS-O-36214 | 174290-51-8 | In Stock |
| (S)-Ibuprofen acyl-β-D-glucuronide | Impurity | CS-F-00225 | 98649-76-4 | Enquire |
| (S)-Ibuprofen Methyl Ester | Impurity | CS-O-52583 | 81576-55-8 | Enquire |
| 1-(4-(1-hydroxy-2-methylpropyl)phenyl)ethanone | Impurity | CS-O-44490 | 1314907-71-5 | In Stock |
| 1-(4-Acetylphenyl)-2-methyl-1-propanone | Impurity | CS-T-47353 | 103931-20-0 | In Stock |
| 2-(4-Isobutylphenyl)prop-2-enoic Acid | Impurity | CS-O-38282 | 6448-14-2 | In Stock |
| 3-Chloro-2,2-dimethylpropyl 2-(4-isobutylphenyl)propanoate | Impurity | CS-O-45691 | 89878-75-1 | Enquire |
| 4-Carboxy-α-methylbenzeneacetic Acid | Impurity | CS-T-10457 | 67381-50-4 | In Stock |
| Dexibuprofen Isopropyl Ester | Impurity | CS-O-52584 | 1114975-39-1 | In Stock |
| Ibuprofen Alcohol | Impurity | CS-T-56572 | 36039-36-8 | In Stock |
| Ibuprofen Arginine | Impurity | CS-DV-00383 | 57469-82-6 | Enquire |
| Ibuprofen EP Impurity A | Impurity | CS-O-11014 | 66622-47-7 | In Stock |
| Ibuprofen EP Impurity F | Impurity | CS-T-56786 | 65322-85-2 | In Stock |
| Ibuprofen EP Impurity K | Impurity | CS-T-54914 | 43153-07-7 | In Stock |
| Ibuprofen Ethyl Ester | Impurity | CS-MM-39791 | 41283-72-1 | In Stock |
| Ibuprofen Impurity 27 | Impurity | CS-EO-02752 | 53500-83-7 | Enquire |
| Ibuprofen Impurity D | Impurity | CS-O-31115 | 938-94-3 | In Stock |
| Ibuprofen impurity N | Impurity | CS-P-00419 | 3585-52-2 | In Stock |
| Ibuprofen Methyl Ester | Impurity | CS-T-29065 | 61566-34-5 | In Stock |
| Ibuprofen Poly(oxy-​1,​2-​ethanediyl) Ester | Impurity | CS-O-42162 | 87553-98-8 | Enquire |
| Ibuprofen Sorbitan Ester | Impurity | CS-O-42218 | ---- | In Stock |
| Ibuprofen Sorbitol Ester (Mixture of Diastereomers) | Impurity | CS-O-11260 | ---- | In Stock |
| Isopropyl 4-acetylbenzoate (Ibuprofen Impurity) | Impurity | CS-O-56508 | 220089-22-5 | Enquire |
| rac a-Hydroxy Ibuprofen | Impurity | CS-T-56078 | 60057-62-7 | In Stock |
| Tetraethyleneglycol Bisibuprofen Ester | Impurity | CS-T-86378 | 1161014-75-0 | In Stock |
| (R)-(-)-Ibuprofen (S)-(+)-Lysinate | Impurity | CS-T-56570 | 157369-85-2 | Enquire |
| (R,S)-N-(1-Phenylethyl) Ibuprofen Amide | Impurity | CS-T-60426 | 121734-79-0 | Enquire |
| (S)-(+)-Ibuprofen (S)-(+)-Lysinate | Impurity | CS-T-56571 | 113403-10-4 | Enquire |
| (S,R)-N-(1-Phenylethyl) Ibuprofen Amide | Impurity | CS-T-60427 | 81576-47-8 | Enquire |
| (S,S)-N-(1-Phenylethyl) Ibuprofen Amide | Impurity | CS-T-60428 | 81576-52-5 | Enquire |
| 1-Ethyl-4-Isobutylbenzene | Impurity | CS-P-06954 | 100319-40-2 | Enquire |
| 2-(2-Isobutylphenyl)propanoic Acid | Impurity | CS-O-41673 | 69363-33-3 | Enquire |
| 2-(4-isobutyrylphenyl)propanamide | Impurity | CS-O-38285 | 1823308-53-7 | Enquire |
| 2,3-Dihydroxypropyl 2-[4-(2-methylpropyl)phenyl]propanoate | Impurity | CS-ZG-88450 | 64622-21-5 | Enquire |
| 2-Methyl-1-[4-(1-methylethyl)phenyl]-1-propanone | Impurity | CS-O-38286 | 72846-62-9 | Enquire |
| 4-(2-Methylpropyl)benzeneethanol | Impurity | CS-T-35029 | 36039-35-7 | Enquire |
| Ibuprofen 1,2,3-Propanetriol Esters (Mixture of Regio- and S... | Impurity | CS-O-38280 | Not Available | Enquire |
| Ibuprofen 1,2-Propylene Glycol Esters (Mixture of Regio- and... | Impurity | CS-O-38281 | Not Available | Enquire |
| Ibuprofen 1,3-Butylene Glycol Esters (Mixture of Regio- and ... | Impurity | CS-O-38283 | Not Available | Enquire |
| Ibuprofen 2,3-Butylene Glycol Ester | Impurity | CS-O-38284 | 95093-59-7 | Enquire |
| Ibuprofen Ester Impurity | Impurity | CS-O-42096 | Not Available | Enquire |
| Ibuprofen impurity at RRT 1.76 | Impurity | CS-O-40458 | Not Available | Enquire |
| Ibuprofen impurity at RRT 1.93 | Impurity | CS-O-40459 | Not Available | Enquire |
| Ibuprofen Impurity G | Impurity | CS-DH-00009 | 1391054-15-1 (mixture) | Enquire |
| Ibuprofen Impurity I | Impurity | CS-DH-00042 | 2143535-26-4 | Enquire |
| Ibuprofen impurity O | Impurity | CS-P-00420 | 64451-76-9 | Enquire |
| Ibuprofen Impurity R | Impurity | CS-DH-00001 | 102120-87-6 | Enquire |
| Ibuprofen Piconol | Impurity | CS-T-94227 | 64622-45-3 | Enquire |
| p-Isobutylstyrene | Impurity | CS-T-29680 | 63444-56-4 | Enquire |
Intermediate
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| 2-[4-(2-Methylpropenyl)phenyl]propionic Acid | Intermediate | CS-T-34757 | 75625-99-9 | In Stock |
Glucuronide
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Ibuprofen acyl-Beta-D-Glucuronide | Glucuronide | CS-O-05712 | 115075-59-7 | In Stock |
Fine Chemicals
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| 4-Acetylbenzoic Acid | Fine Chemicals | CS-M-57488 | 586-89-0 | In Stock |
| 2-(4-Isobutylphenyl)propanal | Fine Chemicals | CS-EO-01231 | 51407-46-6 | Enquire |
| 4-Isobutylbenzoic acid | Fine Chemicals | CS-MM-59587 | 38861-88-0 | Enquire |
Secondary Standards
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Ibuprofen | Secondary Standards | CS-SS-24004-1GM | 15687-27-1 | In Stock |
| Ibuprofen | Secondary Standards | CS-SS-24004 | 15687-27-1 | Enquire |
| Ibuprofen | Secondary Standards | CS-SS-24004-250MG | 15687-27-1 | Enquire |
| Ibuprofen 1,2-Propanetriol Esters | Secondary Standards | CS-SS-25051-50MG | Not Available | Enquire |
| Ibuprofen 1,2-Propylene Glycol Esters | Secondary Standards | CS-SS-25050-50MG | Not Available | Enquire |
| Ibuprofen 1,3-Butylene Glycol Esters | Secondary Standards | CS-SS-25048-100MG | Not Available | Enquire |
| Ibuprofen 2,3-Butylene Glycol Ester | Secondary Standards | CS-SS-25049-50MG | Not Available | Enquire |
| Ibuprofen EP Impurity M | Secondary Standards | CS-SS-26189-50MG | 60057-62-7 | Enquire |
| Ibuprofen Ethyl Ester | Secondary Standards | CS-SS-25045-50MG | 41283-72-1 | Enquire |
| Ibuprofen Impurity A | Secondary Standards | CS-SS-24863-20MG | 66622-47-7 | Enquire |
| Ibuprofen Impurity B | Secondary Standards | CS-SS-24864-20MG | 3585-49-7 | Enquire |
| Ibuprofen Impurity C | Secondary Standards | CS-SS-26003-50MG | 59512-17-3 | Enquire |
| Ibuprofen Impurity F | Secondary Standards | CS-SS-24892-30MG | 65322-85-2 | Enquire |
| Ibuprofen Impurity G | Secondary Standards | CS-SS-24893-50MG | 1391054-15-1 | Enquire |
| Ibuprofen Impurity H | Secondary Standards | CS-SS-24951-50MG | 2143535-25-3 | Enquire |
| Ibuprofen Impurity I | Secondary Standards | CS-SS-24910-50MG | Not Available | Enquire |
| Ibuprofen Impurity K | Secondary Standards | CS-SS-26001-50MG | 43153-07-07 | Enquire |
| IBUPROFEN IMPURITY L | Secondary Standards | CS-SS-26002-50MG | 53949-53-4 | Enquire |
| Ibuprofen Impurity N | Secondary Standards | CS-SS-24865-20MG | 3585-52-2 | Enquire |
| Ibuprofen Impurity O | Secondary Standards | CS-SS-24909-30MG | 64451-76-9 | Enquire |
| Ibuprofen Impurity R | Secondary Standards | CS-SS-24908-50MG | Not Available | Enquire |
| Ibuprofen Intermediate | Secondary Standards | CS-SS-25040-50MG | 121734-80-3 | Enquire |
| Ibuprofen Methyl Ester | Secondary Standards | CS-SS-25044-1ML | 61566-34-5 | Enquire |
| Ibuprofen Related Compound C | Secondary Standards | CS-SS-24187-500MG | 38861-78-8 | Enquire |
| Ibuprofen Related Compound J | Secondary Standards | CS-SS-24905-50MG | 65813-55-0 | Enquire |
Therapeutic
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Ibuprofen amide | Therapeutic | CS-O-05861 | 59512-17-3 | In Stock |
| Ibuprofen Related Compound C | Therapeutic | CS-O-11051 | 38861-78-8 | In Stock |
Analytical Standard
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Dexibuprofen-d3-AR Grad | Analytical Standard | CS-O-02887-10MG | 1329643-44-8 | Enquire |
Chiral
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (S)-(+)-Ibuprofen | Chiral | CS-O-01354 | 51146-56-6 | In Stock |
Pharmaceutical Stds.
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Ibuprofen Dimer | Pharmaceutical Stds. | CS-TB-72019 | 1391054-15-1 | Enquire |