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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Piperidine, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Piperidine impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Piperidine-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Piperidine Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(2R,6R)-rel-tert-Butyl 4-(hydroxymethyl)-2,6-dimethyl-d6-pip... Stable Isotopes CS-T-101740 658076-63-2 (unlabeled) Enquire
(R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5) Stable Isotopes CS-T-94563 1395950-84-1 Enquire
(S)-1-Boc-3-hydroxypiperidine-d4 Stable Isotopes CS-T-100752 Not Available Enquire
1-(Benzyl-d5)-4-[(5-benzyloxy-6-methoxy-1-indanone)-2-yliden... Stable Isotopes CS-T-101857 1217253-68-3 Enquire
1-(Benzyl-d5)-4-[(6-benzyloxy-5-methoxy-1-indanone)-2-yliden... Stable Isotopes CS-T-101856 1185246-73-4 Enquire
1-Aminopiperidine-d10 Hydrochloride Stable Isotopes CS-T-100853 960049-22-3 Enquire
1'-Benzyl-1,4'-bipiperidine-4'-carbonitrile-d10 Stable Isotopes CS-T-101855 1329624-69-2 Enquire
1'-Benzyl-1,4'-bipiperidine-4'-carboxamide-d10 Stable Isotopes CS-T-101854 1329616-19-4 Enquire
1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-ylidene)methyl]piper... Stable Isotopes CS-T-101851 1185239-87-5 Enquire
1-Benzyl-4-methylenepiperidine-[13C,d6] Stable Isotopes CS-I-00495 Not Available Enquire
4-​Piperidine-​d9-​carboxylic Acid Stable Isotopes CS-O-44198 1219798-43-2 Enquire
4-(2-Keto-1-benzimidazolinyl)piperidine-D5 Stable Isotopes CS-O-44676 20662-53-7 (Unlabelled) Enquire
4-(Phenylamino)-1-benzyl-4-piperidinecarbonitrile-d5 Stable Isotopes CS-T-98364 Not Available Enquire
4-(Phenylamino)-1-benzyl-4-piperidinecarboxamide-d5 Stable Isotopes CS-T-98363 Not Available Enquire
4-(Phenylamino]-1-benzyl-4-piperidinecarboxylic Acid Methyl ... Stable Isotopes CS-T-98361 Not Available Enquire
4-(Phenylamino]-1-benzyl-4-piperidinecarboxylic Acid-d4 Stable Isotopes CS-T-98362 Not Available Enquire
4,4-difluoropiperidine-2,2,3,3,5,5,6,6-d8 Stable Isotopes CS-O-39530 2645416-50-6 Enquire
4-[(1-Oxopropyl)phenylamino]-1-benzyl-4-piperidinecarboxylic... Stable Isotopes CS-T-98365 Not Available Enquire
4-[(2-Methoxyphenoxy)methyl]piperidine-d3 Stable Isotopes CS-T-101139 63608-36-6(Unlabelled) Enquire
4-[4-(4-Chlorophenyl)-4-hydroxypiperidine]-4-defluorohaloper... Stable Isotopes CS-T-101678 1797008-46-8 (unlabeled) Enquire
4-Hydroxy-3,3-dimethyl-1-piperidinecarboxylic Acid 1,1-Dimet... Stable Isotopes CS-T-100211 143306-65-4(Unlabeled) Enquire
a-Methyl-2-piperidinemethanol-13C2 Stable Isotopes CS-T-100007 Not Available Enquire
Capivasertib-d4 (piperidine-2,2,6,6-d4) Stable Isotopes CS-O-60046 1143532-39-1 (Unlabeled) Enquire
D-threo-α-Phenyl-2-piperidineacetamide-d10 Stable Isotopes CS-T-102737 160707-37-9(Unlabelled) Enquire
L-threo-a-Phenyl-2-piperidineacetamide-d10 Stable Isotopes CS-T-102818 160707-38-0 (Unlabelled) Enquire
N-(3-Methylphenyl)-4-(2-pyridinyl)-1-piperidineacetamide-d7 ... Stable Isotopes CS-T-100021 Not Available Enquire
N-Nitrosopiperidine-d10(1mg/1ml Methanol) Stable Isotopes CS-O-39632 960049-21-2 In Stock
Pipendoxifene (Piperidine-D10) Stable Isotopes CS-T-103090 198480-55-6(Unlabelled) Enquire
Raloxifene-d10 (piperidine-d10) Stable Isotopes CS-C-01370 2512224-37-0 Enquire
Ritalinic-d9 Acid HCl (piperidine-d9) (mixture of stereoisom... Stable Isotopes CS-C-01256 1276197-13-7 Enquire
trans 1-Benzyl-4-(4-fluorophenyl)-3-methylsulfonatepiperidin... Stable Isotopes CS-T-102965 1217654-31-3 Enquire
trans 1-Benzyl-4-(4-fluorophenyl)-3-piperidinemethanol-d4 Stable Isotopes CS-T-102964 1217676-35-1 Enquire


Metabolite

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Rupatadine piperidine 1-oxide Metabolite CS-O-48060 Not Available Enquire


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(2R,3R,5R)-2-(Hydroxymethyl)-3,5-piperidinediol Impurity CS-O-45555 1220639-18-8 Enquire
(2R,3R,5R)-2-(hydroxymethyl)piperidine-3,5-diol hydrochlorid... Impurity CS-O-47167 2781059-29-6 Enquire
(2R,3S)-2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6-methylb... Impurity CS-O-54508 1346623-11-7 Enquire
(2R,3S)-ethyl 2-(4-(cyclopentylamino)phenyl)-1-(2-fluoro-6-m... Impurity CS-O-54510 1346623-09-3 Enquire
(2R,3S,4R,5S)-3,4,5-tris(benzyloxy)-2-((benzyloxy)methyl)pip... Impurity CS-O-48216 167904-18-9 Enquire
(2R,6R)-1-(tert-butoxycarbonyl)-6-methylpiperidine-2-carboxy... Impurity CS-O-42802 2166006-41-1 Enquire
(2R.3S,4R)-2-(hydroxyethyl)piperidine-3,4-diol hydrochloride Impurity CS-O-47169 Not Available Enquire
(2S,3R,4S,5S,6R)-6-(hydroxymethyl)piperidine-2,3,4,5-tetraol Impurity CS-O-45556 108147-56-4 Enquire
(2S,3R,4S,5S,6R)-6-(hydroxymethyl)piperidine-2,3,4,5-tetraol... Impurity CS-O-47168 Not Available Enquire
(2S,3S,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic acid Impurity CS-O-45554 129797-28-0 Enquire
(2S,3S,4R,5S)-3,4,5-Trihydroxypiperidine-2-carboxylic acid h... Impurity CS-O-47165 1018064-80-6 Enquire
(3S,4R)-1-Methyl-4-phenyl-3-piperidinemethanol Impurity CS-O-59487 176022-03-0 Enquire
(3S,4R,5S,6R)-5-(benzyloxy)-6-(hydroxymethyl)piperidine-3,4-... Impurity CS-O-48215 1704372-47-3 Enquire
(R)-1-[2-[(4-Chlorophenyl)-phenyl-methoxy]ethyl]piperidine h... Impurity CS-O-52902 ---- Enquire
(R)-3-(4-Bromophenyl)piperidine Impurity CS-O-54694 1336754-69-8 Enquire
(S)-3-hydroxy-2,6-Piperidinedione Impurity CS-O-45411 118060-99-4 Enquire
1,1'-[(1,3-dihydro-2-oxo-2H-benzimidazol-1,3-diyl)-3,1-propa... Impurity CS-O-56884 ---- Enquire
1-[2-(Dimethylamino)ethyl]-3-piperidinecarboxylic acid Impurity CS-O-52656 1156272-64-8 Enquire
1-benzyl-4-((1,5,6-trimethoxy-1H-inden-2-yl)methyl)piperidin... Impurity CS-O-36060 Not Available In Stock
3-(Benzo[d][1,3]dioxol-5-yloxy)-4-(4-fluorophenyl)-1-methylp... Impurity CS-EO-03175 Not Available Enquire
3-hydroxy-2,6-Piperidinedione Impurity CS-O-45412 1824138-98-8 Enquire
4-(2,4-difluorobenzoyl)piperidine-1-carbaldehyde Impurity CS-ED-41684 84162-80-1 Enquire
Cis 2-(1,6-dimethylpiperidine-3-yl)propan-2-ol Impurity CS-O-42724 2057-26-3 Enquire
des-4-methylenepiperidine Efinaconazole (2R, 3S) epoxide imp... Impurity CS-O-32442 127000-90-2 Enquire
des-4-methylenepiperidine Efinaconazole (2S, 3R) epoxide imp... Impurity CS-O-32443 135270-07-4 Enquire
Ethyl 4-(4-fluorophenyl)-1-methyl-2,6-dioxo-3-piperidinecarb... Impurity CS-O-47969 202534-94-9 Enquire
Ibrutinib Amino Piperidine dihydrochloride Impurity Impurity CS-ED-00984 1701403-10-2 In Stock
Ibrutinib Amino Piperidine Impurity Impurity CS-O-32105 1022150-12-4 Enquire
Ibrutinib Di-piperidine impurity Impurity CS-O-36026 Not Available In Stock
Ibrutinib Piperidine impurity Impurity CS-O-51886 Not Available Enquire
Ibrutinib Piperidine N-desacryl impurity Impurity CS-O-51887 Not Available Enquire
Lasmiditan 6-bromo Desmethylpiperidine Impurity Impurity CS-O-50090 1486988-21-9 In Stock
Methyl 1-[2-(dimethylamino)ethyl]-3-piperidinecarboxylate Impurity CS-O-52655 1550060-96-2 Enquire
Methyl 4-(4-fluorophenyl)-1-methyl-2,6-dioxo-3-piperidinecar... Impurity CS-O-47970 1558726-44-5 Enquire
progesterone 3,7 dione piperidine impurity Impurity CS-O-49440 Not Available Enquire
progesterone 6-Hydroxy piperidine Impurity Impurity CS-O-49441 Not Available Enquire
rel-1-(1,1-Dimethylethyl) 3-methyl (3R,5R)-5-amino-1,3-piper... Impurity CS-O-54443 1208359-58-3 Enquire
Tert-butyl (R)-3-(4-(7-carbamoyl-2H-indazol-2-yl)phenyl)pipe... Impurity CS-O-54049 ---- Enquire


Intermediate

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(R)-1-(Boc)-5-oxopiperidine-2-carboxylic acid Intermediate CS-ED-42139 1273565-12-0 Enquire
(R)-N-methylpiperidine-3-carboxamide Intermediate CS-BL-00134 1124199-15-0 Enquire
(S)-N-methylpiperidine-3-carboxamide Intermediate CS-BL-00135 1124199-17-2 Enquire
[1,4′-Bipiperidine]-4′-carboxamide, acetate Intermediate CS-O-53104 1333467-36-9 Enquire
1,1-Dimethylethyl 3-[4-[[[3-(methoxycarbonyl)-2-nitrophenyl]... Intermediate CS-O-47076 1038915-99-9 Enquire
1,1-Dimethylethyl 3-fluoro-5-hydroxy-1-piperidinecarboxylate Intermediate CS-O-57412 2386139-89-3 Enquire
1-[(4-Methoxyphenyl)methyl]-4-piperidinemethanamine Intermediate CS-O-49625 117702-38-2 Enquire
1-[[4-[[(2-Hydroxyethyl)methylamino]carbonyl]phenyl]methyl]-... Intermediate CS-O-50111 2641256-93-9 Enquire
1-Benzyl-4-methyl-3-(methylamino)piperidine dihydrochloride Intermediate CS-BL-00174 1228879-37-5 Enquire
1-Ethyl-3-piperidinemethanol Intermediate CS-O-49662 54525-19-8 Enquire
2,5-Piperidinedione Intermediate CS-O-47552 52065-78-8 Enquire
Benzyl 2-(4-cyanophenyl)-4-oxopiperidine-1-carboxylate Intermediate CS-O-48052 1644667-45-7 Enquire
Methyl (2R)-1-Boc-5-oxopiperidine-2-carboxylate Intermediate CS-ED-42138 448963-98-2 Enquire
tert-Butyl 4-((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindoli... Intermediate CS-ED-41883 2520105-41-1 Enquire
Tert-butyl 4-(pyrrolidin-3-yl)piperidine-1-carboxylate Intermediate CS-O-53856 1314771-79-3 Enquire
Trans-1-boc-4-aminomethyl-3-hydroxypiperidine Intermediate CS-ED-41941 219975-84-5 Enquire


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
1-((9H-Fluoren-9-yl)methyl)piperidine Fine Chemicals CS-O-58688 35661-58-6 Enquire
1-[2-(2-Hydroxyethoxy)Ethyl]Piperidine Fine Chemicals CS-O-16452 3603-43-8 In Stock
1-Methylpiperidine-4-carbonyl chloride hydrochloride Fine Chemicals CS-O-59936 7462-84-2 Enquire
2-(Methoxymethyl)piperidine hydrochloride Fine Chemicals CS-O-54251 688809-98-5 Enquire
4-((tert-Butoxycarbonyl)amino)piperidine-4-carboxylic acid Fine Chemicals CS-O-59013 252720-31-3 Enquire
4-(4-Chlorophenyl)piperidine hydrochloride Fine Chemicals CS-ED-41877 6652-06-8 Enquire
4-Bromomethylpiperidine Fine Chemicals CS-O-49950 69719-84-2 Enquire
N-Ethylpiperidine Fine Chemicals CS-O-57203 766-09-6 Enquire
Tert-butyl (2R)-3-cyano-2-methyl-4-oxopiperidine-1-carboxyla... Fine Chemicals CS-O-58997 3008218-44-5 Enquire
Tert-Butyl 3-((chlorosulfonyl)methyl)piperidine-1-carboxylat... Fine Chemicals CS-BL-00137 1260663-21-5 Enquire


Nitrosamine

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
1′-Nitroso-1,4′-bipiperidine (Mixture of E/Z Isomers) Nitrosamine CS-O-50451 2639422-25-4 In Stock
1-Nitroso-2,2,6,6-Tetramethylpiperidine Nitrosamine CS-ED-01786 6130-93-4 In Stock
1-Nitroso-4-piperidinecarboxamide Nitrosamine CS-O-51894 1254360-38-7 In Stock
1-nitroso-alpha-phenyl-2-piperidine acetamide Nitrosamine CS-O-48179 Not Available Enquire
1-Nitroso-Pyrrolopiperidine Nitrosamine CS-O-58967 ---- Enquire
3-Hydroxy-N-Nitrosopiperidine (Mixture of Isomers) Nitrosamine CS-O-40186 55556-85-9 In Stock
4-Chloro-N-nitrosopiperidine Nitrosamine CS-EO-02602 65445-61-6 Enquire
Alogliptin piperidine Nitroso Impurity Nitrosamine CS-O-57444 ---- Enquire
Di-Nitroso- Pyrrolopiperidine ( Mix of isomers ) Nitrosamine CS-O-44046 Not Available In Stock
Ethyl 1-nitrosopiperidine-4-carboxylate Nitrosamine CS-O-54886 160114-74-9 Enquire
NITROSOISONIPECOTICACID Nitrosamine CS-O-45553 6238-69-3 In Stock
N-Nitroso 4-(p-toluidino)piperidine Nitrosamine CS-O-52833 Not Available In Stock
N-Nitroso Ibrutinib Amino piperidine Impurity Nitrosamine CS-O-50034 Not Available In Stock
N-nitroso piperidine -4-one impurity Nitrosamine CS-T-95834 55556-91-7 In Stock
N-Nitroso-3-aminopiperidine (Mixture of Isomers) Nitrosamine CS-T-94050 2819242-71-0 In Stock
N-Nitroso-3-aminopiperidine 1mg/mL in methanol Nitrosamine CS-O-43406 2819242-71-0 Enquire
N-Nitroso-4-hydroxypiperidine Nitrosamine CS-O-50291 55556-93-9 In Stock
N-nitroso-piperidine-4-amine Nitrosamine CS-O-58132 ---- Enquire


Stable Isotope Reagent

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(R)-3-Amino(piperidine-3-d1 )-2,6-dione HCl Stable Isotope Reagent CS-C-01662 2708341-27-7 Enquire
1-Piperidine-d10 -carbonyl Chloride Stable Isotope Reagent CS-C-02046 1219803-31-2 Enquire
2,2,6,6-Tetramethylpiperidine-d8 -1-oxyl Stable Isotope Reagent CS-C-01690 205679-68-1 Enquire
4-Amino-2,2,6,6-tetramethylpiperidine-d17 ;1-15 N-1-oxyl Stable Isotope Reagent CS-C-01666 97461-87-5 Enquire
4-Hydroxy-2,2,6,6-tetramethylpiperidine-d17-1-15N-1-oxyl Stable Isotope Reagent CS-C-02017 90429-66-6 Enquire
4-Hydroxy-2,2,6,6-tetramethylpiperidine-d17-1-oxyl Stable Isotope Reagent CS-C-02016 100326-46-3 Enquire
4-Hydroxypiperidine-3,3,4,5,5-d5 Stable Isotope Reagent CS-C-02011 1219799-35-5 Enquire
4-Hydroxypiperidine-3,3,4,5,5-d5-N-t-BOC Stable Isotope Reagent CS-C-02012 1523606-18-9 Enquire
4-Hydroxypiperidine-D4 Stable Isotope Reagent CS-O-46058 1014695-51-2 Enquire
4-Oxo-2,2,6,6-tetramethylpiperidine-d16-1-oxyl Stable Isotope Reagent CS-C-01653 36763-53-8 Enquire
4-Oxo-2,2,6,6-tetramethylpiperidine-d17 Stable Isotope Reagent CS-C-01652 52168-48-6 Enquire
4-Piperidine-d9- carboxamide Stable Isotope Reagent CS-C-02047 1219803-20-9 Enquire
Methyl 4-Piperidine-3,3,5,5-d4-acetate HCl Stable Isotope Reagent CS-C-02122 Not Available Enquire
tert-butyl 4-aminopiperidine-1-carboxylate-2,2,3,3,4,5,5,6,6... Stable Isotope Reagent CS-O-57466 2891512-50-6 Enquire
tert-Butyl 4-aminopiperidine-1-carboxylate-3,3,4,5,5-d5 Stable Isotope Reagent CS-O-57467 1340546-55-5 Enquire


Fluorinated Compounds

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
4-(Trifluoromethyl)piperidine Fluorinated Compounds CS-O-58077 657-36-3 Enquire


Building Blocks

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol Building Blocks CS-O-47524 126663-71-6 Enquire
1-[2-[5-Methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-4... Building Blocks CS-O-46528 1003319-95-6 Enquire
4-(3,4-dichlorophenyl)-2,6-dioxopiperidine-3,5-dicarbonitril... Building Blocks CS-BX-02585 958809-52-4 Enquire
4-Hydroxy-1-(2-hydroxyethyl)-2,2,6,6-tetramethylpiperidine Building Blocks CS-DE-01593 52722-86-8 Enquire
cis-3,5-Dimethylpiperidine Building Blocks CS-T-95991 14446-75-4 Enquire
Ethyl 1-benzylpiperidine-2-carboxylate Building Blocks CS-O-55355 77034-34-5 Enquire
Ethyl 4-(4-methyl-1-piperazinyl)-1-piperidinecarboxylate Building Blocks CS-O-57333 415968-25-1 Enquire
N-(4-Nitrophenyl)-1-piperidinecarboxamide Building Blocks CS-O-58351 2589-20-0 Enquire
Phenylmethyl (2R,5R)-5-amino-2-methyl-1-piperidinecarboxylat... Building Blocks CS-O-55632 1207853-72-2 Enquire
Phenylmethyl (2R,5S)-5-amino-2-methyl-1-piperidinecarboxylat... Building Blocks CS-O-55628 1290191-65-9 Enquire
Phenylmethyl (2S,5S)-5-amino-2-methyl-1-piperidinecarboxylat... Building Blocks CS-O-55634 1290191-79-5 Enquire
tert-Butyl 4-(3-hydroxypropyl)piperidine-1-carboxylate Building Blocks CS-EC-00091 156185-63-6 Enquire


Deuterated Reagents

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Piperidine-2,2,6,6-d4 Deuterated Reagents CS-T-94279 1001337-60-5 Enquire