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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Tadalafil, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Tadalafil impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Tadalafil-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Tadalafil Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2-Hydroxyethyl Nortadalafil-d4 Stable Isotopes CS-T-100208 Not Available Enquire
2-Hydroxypropyl-d6 Nortadalafil Stable Isotopes CS-T-101040 Not Available Enquire
Chloropretadalafil-13C2 Stable Isotopes CS-T-97688 Not Available Enquire
N-Butyl Nortadalafil-d9 Stable Isotopes CS-T-97727 Not Available Enquire
N-Desmethyl-N-cyclopentyl cis-ent-Tadalafil-D4 Stable Isotopes CS-T-100801 Not Available Enquire
N-Desmethyl-N-cyclopentyl Tadalafil-D4 Stable Isotopes CS-T-100802 Not Available Enquire
N-nitroso Tadalafil D3 Stable Isotopes CS-O-53317 ---- Enquire
N-Octyl Nortadalafil-d17 Stable Isotopes CS-T-97246 Not Available Enquire
Tadalafil-13C,d3 Stable Isotopes CS-O-15332 1261364-86-6 In Stock
Tadalafil-13C2,d3 Stable Isotopes CS-T-95023 171596-29-5(Unlabeled) Enquire
Tadalafil-d3 Stable Isotopes CS-O-02787 960226-55-5 In Stock


API

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Tadalafil API CS-O-02425 171596-29-5 In Stock
Acetaminotadalafil API CS-T-46880 1446144-71-3 Enquire


Metabolite

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2'-Oxo Tadalafil Metabolite CS-O-05922 1346602-17-2 In Stock
Tadalafil 3-methyl-4-glucuronide catechol Metabolite CS-ED-41803 378788-18-2 Enquire
Tadalafil Methyl Catchelol Metabolite CS-T-103269 378788-16-0 Enquire


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Chloropretadalafil (S,S-isomer) Impurity CS-T-96075 629652-42-2 Enquire
N-Desmethyl Tadalafil Impurity CS-O-08230 171596-36-4 In Stock
Tadalafil Acid Impurity Impurity CS-O-58128 406938-39-4 Enquire
Tadalafil Acid Impurity Hydrochloride Impurity CS-T-96146 474668-76-3 Enquire
Tadalafil chloroacetyl Impurity Impurity CS-T-96147 2058231-08-4 Enquire
Tadalafil Chloroacetyle Impurity (1S,3R-isomer) Impurity CS-T-04844 629652-40-0 Enquire
Tadalafil Dichloro Impurity Impurity CS-O-58109 1598416-08-0 Enquire
Tadalafil EP Impurity A Impurity CS-O-08227 171596-27-3 In Stock
Tadalafil EP Impurity B Impurity CS-O-08228 629652-72-8 In Stock
Tadalafil EP Impurity C Impurity CS-O-08229 171596-28-4 In Stock
Tadalafil EP Impurity C hydrochloride trihydrate Impurity CS-EO-03870 171596-28-4 (Freebase) Enquire
Tadalafil EP Impurity D Impurity CS-P-08134 Not Available Enquire
Tadalafil EP Impurity G Impurity CS-AQ-00153 2520114-46-7 In Stock
Tadalafil EP Impurity H Impurity CS-T-43082 1978322-98-3 In Stock
Tadalafil EP Impurity I Impurity CS-EO-01798 2378614-29-8 In Stock
Tadalafil EP Impurity I (Hydrate) Impurity CS-EO-03871 2378614-29-8 (Freebase) Enquire
Tadalafil Hydroxypiperidone Impurity CS-T-96067 1978322-99-4 Enquire
Tadalafil Impurity 1 Impurity CS-T-35159 171596-41-1 In Stock
Tadalafil Impurity 6 Impurity CS-P-02138 36060-94-3 Enquire
Tadalafil Impurity D (R,R)Isomer Impurity CS-O-49664 2194574-01-9 Enquire
Tadalafil Impurity D (R,S)Isomer Impurity CS-O-49666 2747990-82-3 Enquire
Tadalafil Impurity E Impurity CS-AQ-00151 2520114-41-2 In Stock
Tadalafil Open Ring Acid Impurity CS-O-60261 2058231-15-3 Enquire
Tadalafil Related Compound 2 Impurity CS-O-43415 2169996-11-4 Enquire
(1S,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrid... Impurity CS-T-48663 171596-43-3 Enquire
1,3-Benzodioxole-5-glycolic Acid Impurity CS-O-41174 27738-46-1 Enquire
Amino Tadalafil Impurity CS-T-48087 385769-84-6 Enquire
N-Ethyl tadalafil Impurity CS-ED-42076 1609405-34-6 Enquire
Tadalafil EP Impurity F Impurity CS-AQ-00152 2747958-44-5 Enquire
Tadalafil EP Impurity I Impurity CS-AQ-00154 Not Available Enquire
Tadalafil Impurity 3 Impurity CS-EO-01176 2520114-84-3 Enquire
Tadalafil Impurity 37 Impurity CS-P-08600 Not Available Enquire
Tadalafil Impurity 4 Impurity CS-EO-01177 Not Available Enquire
Tadalafil Impurity 5 Impurity CS-EO-01178 1797099-86-5 Enquire
Tadalafil Impurity 7 Impurity CS-T-48664 171596-42-2 Enquire
Tadalafil Ketolactam Impurity CS-T-86883 1346605-38-6 Enquire


Intermediate

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2,3-(Methylenedioxy)benzaldehyde Intermediate CS-AC-01617 7797-83-3 In Stock
D-Tryptophan Methyl Ester Hydrochloride Intermediate CS-M-57693 14907-27-8 In Stock


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Tetrahydropiperine Fine Chemicals CS-E-05229 23434-88-0 Enquire


Nitrosamine

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2,9-dinitroso Tadalafil Impurity Nitrosamine CS-O-44943 Not Available Enquire
2-nitroso Tadalafil Impurity Nitrosamine CS-O-44944 Not Available Enquire
9-nitroso Tadalafil Impurity Nitrosamine CS-O-44945 Not Available Enquire
N-Nitroso Chloropretadalafil Nitrosamine CS-O-44942 Not Available Enquire
N-nitroso Tadalafil Nitrosamine CS-O-39020 ---- Discontinued
N-Nitroso Tadalafil - Impurity A Nitrosamine CS-O-51671 Not Available Enquire
N-Nitroso Tadalafil Chloroacetyl acid Impurity Nitrosamine CS-O-54708 ---- Enquire
N-Nitroso Tadalafil EP Impurity B Nitrosamine CS-O-51672 Not Available Enquire
N-Nitroso Tadalafil Impurity 13 Nitrosamine CS-O-52924 ---- Enquire
N-Nitroso TADALAFIL IMPURITY C Nitrosamine CS-O-51669 Not Available Enquire
N-Nitroso Tadalafil Open Ring Acid Nitrosamine CS-O-60237 ---- Enquire


Therapeutic

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Tadalafil Desmethylene Impurity Therapeutic CS-O-08226 171489-03-5 In Stock