Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Biotin, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Biotin impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Biotin-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Our Biotin-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Biotin Related Compounds
Stable Isotopes
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| 13-Amino-4,7,10-trioxatridecanyl-2,2’,3,3’,11,11’,12,12’-d8)... | Stable Isotopes | CS-T-66305 | 1217717-09-3 | Enquire |
| 5-[2-Biotinylamidoethyl]-dithiopropionamido]-3,7-diaza-4,6-d... | Stable Isotopes | CS-T-96422 | Not Available | Enquire |
| 6-[2-Biotinylamidoethyl]-dithiopropionamido]-4,8-diaza-5,7-d... | Stable Isotopes | CS-T-96421 | Not Available | Enquire |
| 6-[2-Biotinylamidoethyl]-dithiopropionamido]-5,9-diaza-6,8-d... | Stable Isotopes | CS-T-96420 | Not Available | Enquire |
| 6-N-Biotinylaminohexyl Isopropyl-d7 Phosphorofluoridate, Hem... | Stable Isotopes | CS-T-96419 | 1246812-28-1 | Enquire |
| Biotin 13C5 | Stable Isotopes | CS-O-34760 | 58-85-5 (Unlabeled) | Enquire |
| Biotin sulfoxide 13C5 | Stable Isotopes | CS-EK-02244 | 3376-83-8 unlabeled | Enquire |
| Biotin-2′,2′,3′,3′-d4 | Stable Isotopes | CS-BX-00918 | 1799489-82-9 | Enquire |
| Biotin-d2 | Stable Isotopes | CS-O-11977 | 1217481-41-8 | In Stock |
| Biotinyl Cystamine-d4 | Stable Isotopes | CS-T-96417 | 1322625-65-9 | Enquire |
| D-Biotin-d2 (pentanoic-2,2-d2) | Stable Isotopes | CS-C-01433 | 58-85-5 (Unlabelled) | Enquire |
| erythro-ω-Amino Sphingosine Biotinamide-d4 | Stable Isotopes | CS-T-96423 | Not Available | Enquire |
| FP-Biotin-d4 | Stable Isotopes | CS-T-76196 | 1219356-78-1 | Enquire |
| N’-(13-Iodoacetamido-4,7,10-trioxatridecanyl-2,2’,3,3’,11,11... | Stable Isotopes | CS-T-96415 | Not Available | Enquire |
| Sulfo-NHS-LC-Biotin-D10 | Stable Isotopes | CS-T-104065 | 191671-46-2(unlablled) | Enquire |
| VITAMIN B7 (BIOTIN) (3',3',4',4'-D4) | Stable Isotopes | CS-TA-30496 | 1217850-77-5 | Enquire |
API Standards
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Biotin HPDP | API Standards | CS-T-49126 | 129179-83-5 | Enquire |
| Biotin Hydrazide | API Standards | CS-T-49127 | 66640-86-6 | Enquire |
| D-Biotin | API Standards | CS-P-00358 | 58-85-5 | In Stock |
| Fluorescein Biotin | API Standards | CS-T-77664 | 134759-22-1 | Enquire |
| FP-Biotin | API Standards | CS-T-55073 | 259270-28-5 | Enquire |
| N-Biotinyl p-Aminophenyl Arsinic Acid | API Standards | CS-T-49138 | 212391-23-6 | Enquire |
| Sulfo-NHS-Biotin | API Standards | CS-T-61534 | 119616-38-5 | Enquire |
Metabolites
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Biotin Sulfoxide | Metabolites | CS-P-00736 | 23015-53-4 | Enquire |
| Biotinyl tyramide | Metabolites | CS-O-43675 | 41994-02-9 | Enquire |
| Biotinylated isoxazole | Metabolites | CS-O-43690 | 1377605-22-5 | Enquire |
| Rac-Selenobiotin | Metabolites | CS-P-00735 | 57956-29-3 | Enquire |
Impurities
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| "(+)-Biotin 4-Amidobenzoic Acid, Sodium Salt" | Impurities | CS-T-06529 | 102418-74-6 | Enquire |
| 90%)"" rel="follow" style=''> "1,17-Bisbiotinylamino-3,6,9,12,15-pentaoxaheptadecane (>90%... | Impurities | CS-T-49205 | 440680-87-5 | Enquire |
| "1-O-(4,4’-Dimethoxytrityl)-3-O-(N-biotinyl-3-aminopropyl)gl... | Impurities | CS-T-91148 | 131622-83-8 | Enquire |
| "2,7-Bis(alloxycarbonylamino)-9-(biotinylaminoethylamino)acr... | Impurities | CS-T-49186 | 1219125-65-1 | Enquire |
| "6-[4'-N-(biotinylaminopropyl-NHCOCH2-PEG2-acetyl)-aminophen... | Impurities | CS-T-49139 | 1522299-17-7 | Enquire |
| "6-N-Biotinylaminohexyl Isopropyl Phosphorofluoridate, Hemih... | Impurities | CS-T-49136 | 353754-93-5 | Enquire |
| "BNP, D-Biotin 4-nitrophenyl ester" | Impurities | CS-DL-00558 | 33755-53-2 | Enquire |
| (-)-Biotin Sulfoxide | Impurities | CS-T-49115 | 3376-83-8 | Enquire |
| (+)-Biotin (+)-Sulfoxide | Impurities | CS-T-49116 | 10406-89-0 | Enquire |
| (+)-Biotin-(PEO)4-amine | Impurities | CS-DL-00698 | 359860-27-8 | Enquire |
| (+)-Biotin-PFP-ester | Impurities | CS-DL-00795 | 120550-35-8 | Enquire |
| (+/-)-Epiallobiotin | Impurities | CS-O-33618 | 68225-55-8 | Enquire |
| 2-[2-[2-[2-[6-(Biotinylaminohexanoyl]aminoethoxy]ethoxy]etho... | Impurities | CS-T-49134 | 207971-23-1229 | Enquire |
| 3-[[2-(Biotinamido)ethyl]dithio]propionic Acid 4'-(Hydroxyme... | Impurities | CS-T-49119 | 1255087-87-6 | Enquire |
| 3-[2-N-(Biotinyl)aminoethyldithio]propanoic Acid | Impurities | CS-T-06562 | 104582-29-8 | Enquire |
| 5-Oxohexyl Biotin | Impurities | CS-T-38446 | 1160188-05-5 | Enquire |
| 6-N-Biotinylaminohexyl Isopropyl Hydrogenphosphonate | Impurities | CS-T-06572 | 224583-37-3 | Enquire |
| 9-Methyl Biotin | Impurities | CS-T-58005 | 415725-35-8 | Enquire |
| Acriflavin-Biotin Conjugate | Impurities | CS-T-47438 | 1041387-90-9 | Enquire |
| Allobiotin | Impurities | CS-ED-00357 | 5652-41-5 | Enquire |
| Biotin Diacid | Impurities | CS-T-06538 | 57671-79-1 | Enquire |
| Biotin EP Impurity C (Diamino Biotin) | Impurities | CS-T-52409 | 22342-46-7 | Enquire |
| Biotin EP Impurity C Dihydrochloride | Impurities | CS-O-59506 | 22342-46-7 (Freebase) | Enquire |
| Biotin EP Impurity E (Mixture of Isomers) | Impurities | CS-P-07294 | "76335-62-1, 57229-92-2" | Enquire |
| Biotin Impurity 1 | Impurities | CS-P-07292 | 26339-40-2 | Enquire |
| Biotin Impurity 3 | Impurities | CS-T-47790 | 111790-37-5 | Enquire |
| Biotin Impurity 4 | Impurities | CS-P-02236 | 111822-45-8 | Enquire |
| Biotin Impurity C DiHydrochloride | Impurities | CS-P-07293 | 412308-26-0 (free base) | Enquire |
| Biotin-11-dUTP | Impurities | CS-T-49123 | 1221498-88-9 | Enquire |
| Biotinamidocaproate Tobramycin Amide | Impurities | CS-T-49118 | 419573-19-6 | Enquire |
| Biotin-PEG3-Azide | Impurities | CS-DL-00629 | 875770-34-6 | Enquire |
| Biotin-Vitamin B7 | Impurities | CS-O-08437 | 58-85-5 | In Stock |
| Biotinyl Tobramycin Amide | Impurities | CS-T-49154 | 419573-18-5 | Enquire |
| D-Biotin Dimer Acid | Impurities | CS-T-49124 | 1163708-46-0 | Enquire |
| Epibiotin | Impurities | CS-O-33617 | 4375-00-2 | Enquire |
| erythro-ω-Amino Sphingosine Biotinamide | Impurities | CS-T-66201 | 752987-57-8 | Enquire |
| erythro-ω-Amino Sphingosine Biotinamide Phosphate | Impurities | CS-T-66302 | 799812-63-8 | Enquire |
| EZ-Link NHS-PEG12-Biotin | Impurities | CS-T-83381 | 365441-71-0 | Enquire |
| N-(15,16-Dihydroxy-4,7,10,13-tetraoxahexadecyl-D-(+)-biotina... | Impurities | CS-T-91210 | 869354-59-6 | Enquire |
| N-(2-Aminoethyl)-N’-(2-Sulfothioacetamid)biotinamide, Sodium... | Impurities | CS-T-65633 | 1330264-29-3 | Enquire |
| N1-(4-(t-Butyl)benzoyl)-D-(+)biotin 2-Nitrophenyl Ester | Impurities | CS-T-69368 | 869354-61-0 | Enquire |
| N1-(Dimethoxytrityl)-D-(+)biotin 2-Nitrophenyl Ester | Impurities | CS-T-91456 | 869354-63-2 | Enquire |
| N2-t-Boc-N6-(biotinamido-6-N-caproylamido)lysine | Impurities | CS-T-07472 | 102910-26-9 | Enquire |
| N-Biotinyl Dopamine | Impurities | CS-T-49148 | 241142-94-9 | Enquire |
| N-Biotinyl Glycine | Impurities | CS-T-49150 | 160390-90-9 | Enquire |
| N-Biotinyl-12-aminododecanoic Acid | Impurities | CS-T-06554 | 135447-73-3 | Enquire |
| N-Biotinyl-12-aminododecanoyltobramycin Amide | Impurities | CS-T-49130 | 419573-20-9 | Enquire |
| N-Biotinylcaproic Acid | Impurities | CS-T-06586 | 72040-64-3 | Enquire |
| N-Biotinylcaproylaminocaproic Acid | Impurities | CS-T-06590 | 89889-51-0 | Enquire |
| N-Biotinylcaproylaminocaproylaminoethyl Methanethiosulfonate | Impurities | CS-T-49144 | 1038749-81-3 | Enquire |
| N-Boc-Biotinylethylenediamine | Impurities | CS-T-07475 | 225797-46-6 | Enquire |
| N-d-Biotinyl-7-amino-4-methylcoumarin | Impurities | CS-T-49137 | 191223-35-5 | Enquire |
| N-Succinimido (+)-Biotin | Impurities | CS-T-61471 | 35013-72-0 | Enquire |
| Sulfosuccinimidyl 3-[[2-(Biotinamido)ethyl] dithio]propionat... | Impurities | CS-T-61540 | 325143-98-4 | Enquire |
EP Standards
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Biotin (B1116000) | EP Standards | CS-EG-00922 | 58-85-5 | Enquire |
| Biotin for system suitability (Y0001978) | EP Standards | CS-EG-00193 | 58-85-5 | Enquire |
Intermediates
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| "1-Biotinylamino-3,6,9-trioxaundecane-11-bromide" | Intermediates | CS-T-49141 | 1041766-91-9 | Enquire |
| "N,N-Bis(ethylmethanethiosulfonate) Biotinamide" | Intermediates | CS-T-49315 | 1217607-38-9 | Enquire |
| "N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediamine" | Intermediates | CS-T-49151 | 93285-75-7 | Enquire |
| (+)-Biotin Methyl Ester | Intermediates | CS-T-49122 | 608-16-2 | Enquire |
| 10-Benzyloxyethoxyphosphinyl-N-biotinamidopentyldecanamide | Intermediates | CS-T-05992 | 1246814-51-6 | Enquire |
| 10-Ethoxyphosphinyl-N-biotinamidopentyldecanamide | Intermediates | CS-T-22415 | 1246814-63-0 | Enquire |
| 1N-Benzyl Biotin | Intermediates | CS-T-48823 | 76335-62-1 | Enquire |
| 2-[N2-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-N6-(6-biotinamido... | Intermediates | CS-ED-12055 | 1356841-73-0 | Enquire |
| 2-[N2-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-N6-(6-biotinamido... | Intermediates | CS-ED-12056 | 1356383-18-0 | Enquire |
| 2-{N2-[N6-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-6-aminocaproy... | Intermediates | CS-ED-12053 | 1217773-33-5 | Enquire |
| 2-{N2-[N6-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-6-aminocaproy... | Intermediates | CS-ED-12054 | 1356841-34-3 | Enquire |
| 25-Hydroxy Vitamin D3 3,3'-Biotinylaminopropyl Ether | Intermediates | CS-T-56536 | 193278-59-0 | Enquire |
| 25-OH vitamin D3-DPEG4-Biotin | Intermediates | CS-Y-00136 | Not Available | Enquire |
| 25-OH vitamin D3-LC-Biotin | Intermediates | CS-Y-00137 | 193278-61-4 | Enquire |
| 3-(4-(N-Biotinoyl-6-aminocaproyloxy)phenyl)propionic Acid | Intermediates | CS-T-49131 | 83592-10-3 | Enquire |
| 3N-Benzyl Biotin | Intermediates | CS-T-48824 | 57229-92-2 | Enquire |
| 6-(Biotinylamino)thiocaproic Acid S-Ethyl Ester | Intermediates | CS-T-49140 | 353754-94-6 | Enquire |
| 6-[2-Biotinylamidoethyl]-dithiopropionamido]-4,8-diaza-5,7-d... | Intermediates | CS-ED-17521 | 1044220-56-5 | Enquire |
| 6-N-Biotinylaminohexyl Hydrogenphosphonate | Intermediates | CS-T-49135 | 224583-35-1 | Enquire |
| 9-Biotinylamino-4,7-dioxanonanoic acid n-hydroxysuccinimidyl... | Intermediates | CS-AC-10680 | 596820-83-6 | Enquire |
| AC-Tyr-val-lys(biotinyl)-asp-2,6-dimethylbenzoyloxymethylket... | Intermediates | CS-ED-40509 | 154719-25-2 | Enquire |
| ADIBO-NH-PEG2-Biotin | Intermediates | CS-AC-10653 | 1255942-07-4 | Enquire |
| Azido-peg11-biotin conjugate | Intermediates | CS-AC-10673 | 956494-20-5 | Enquire |
| Biotin Sulfone | Intermediates | CS-T-49117 | 40720-05-6 | Enquire |
| Biotin-[2-(2-pyridyldithio)ethylamide] | Intermediates | CS-T-49128 | 112247-65-1 | Enquire |
| Biotinamidocaproyl hydrazine | Intermediates | CS-CE-00676 | 109276-34-8 | Enquire |
| Biotin-dpeg(4)-COOH | Intermediates | CS-AC-10658 | 721431-18-1 | Enquire |
| Biotin-maleimide | Intermediates | CS-O-48400 | 116919-18-7 | Enquire |
| Biotin-peg11-amine | Intermediates | CS-AC-10664 | 604786-74-5 | Enquire |
| Biotin-PEG2-Acid | Intermediates | CS-ED-13679 | 1365655-89-5 | Enquire |
| Biotin-PEG2-Azide | Intermediates | CS-ED-13676 | 945633-30-7 | Enquire |
| Biotin-peg3-acid | Intermediates | CS-AC-10668 | 252881-76-8 | Enquire |
| Biotin-PEG3-hydrazide | Intermediates | CS-ED-13684 | 1381861-94-4 | Enquire |
| Biotin-PEG3-NHS ester | Intermediates | CS-ED-13683 | 1253286-56-4 | Enquire |
| Biotin-peg4-amine | Intermediates | CS-AC-10709 | 663171-32-2 | Enquire |
| Biotin-peg4-nhs ester | Intermediates | CS-AC-10650 | 459426-22-3 | Enquire |
| Biotin-peg6-alcohol | Intermediates | CS-AC-10702 | 906099-89-6 | Enquire |
| Biotin-PEG8-NHS ester | Intermediates | CS-ED-13689 | 2143968-03-8 | Enquire |
| Biotin-sar-oh | Intermediates | CS-ED-13691 | 154024-76-7 | Enquire |
| Biotinyl Pyridinyldithio N-Hydroxysuccinimide Alanine Ester | Intermediates | CS-T-49153 | 1356933-91-9 | Enquire |
| Biotinyl Tyramide | Intermediates | CS-T-49155 | 41994-02-9 | Enquire |
| Biotinyl-6-aminoquinoline | Intermediates | CS-CE-00679 | 91853-89-3 | Enquire |
| Biotinyl-AEEAc-AEEAc-OH | Intermediates | CS-ED-13681 | 1301706-65-9 | Enquire |
| Biotinyl-Gly-Gly-OH | Intermediates | CS-ED-13699 | 120447-60-1 | Enquire |
| Bisnorbiotin | Intermediates | CS-T-49387 | 16968-98-2 | Enquire |
| D-Desthiobiotin | Intermediates | CS-T-89060 | 533-48-2 | Enquire |
| Desthiobiotin N-Hydroxysuccinimide Ester | Intermediates | CS-T-88921 | 80750-24-9 | Enquire |
| Desthiobiotin-TEG Azide | Intermediates | CS-T-88738 | 1306615-47-3 | Enquire |
| Fmoc-L-Lys(Biotinyl)-OH | Intermediates | CS-BH-00011 | 146987-10-2 | Enquire |
| Methyl N-Biotinyl-6-amino-2-naphthonate | Intermediates | CS-T-58006 | 1041143-49-0 | Enquire |
| N-(3-Azidopropyl)biotinamide | Intermediates | CS-ED-11980 | 908007-17-0 | Enquire |
| N-[2-[2-(2-Aminoethoxy)ethoxy]ethyl] biotinamide | Intermediates | CS-AC-10688 | 138529-46-1 | Enquire |
| N2-t-Boc-N6-(biotinamido-6-N-caproylamido)lysine N-Hydroxysu... | Intermediates | CS-T-49490 | 102910-27-0 | Enquire |
| N-Biotinylaminoethyl Methanethiosulfonate | Intermediates | CS-T-49132 | 162758-04-5 | Enquire |
| N-Biotinylcaproylaminoethyl Methanethiosulfonate | Intermediates | CS-T-49146 | 353754-95-7 | Enquire |
| N-Biotinyl-n'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-dia... | Intermediates | CS-AC-10657 | 305372-39-8 | Enquire |
| N-Biotinyl-N-cysteinyl Ethylenediamine | Intermediates | CS-T-49147 | 288144-42-3 | Enquire |
| N-Biotinyl-N'-maleimido-ethylenediamine | Intermediates | CS-T-49152 | 139554-72-6 | Enquire |
| NHS β Biotin | Intermediates | CS-T-59241 | 142439-92-7 | Enquire |
| Norbiotin | Intermediates | CS-O-49613 | 669-72-7 | Enquire |
| Photobiotin Acetate Salt | Intermediates | CS-T-84380 | 96087-38-6 | Enquire |
| Pyrimethamine Biotin | Intermediates | CS-O-13016 | 1219358-20-9 | Enquire |
| Succinimidyl-6-(biotinamido) Hexanoate | Intermediates | CS-T-61477 | 72040-63-2 | Enquire |
| Succinimidyl-6-[6-(biotinamido)caproyl]caproylate | Intermediates | CS-T-61478 | 89889-52-1 | Enquire |
| Sulfo-N-succinimidyl 6-(biotinamido) hexanoate Sodium Salt | Intermediates | CS-T-61541 | 191671-46-2 | Enquire |
| Sulphosuccinimido biotin | Intermediates | CS-CE-00671 | 194041-65-1 | Enquire |
| Sulphosuccinimidyl-2-(biotinamido)ethyl-1,3-dithiopropionate | Intermediates | CS-CE-00674 | 858128-64-0 | Enquire |
| Sulphosuccinimidyl-6-(biotinamido)hexanoate | Intermediates | CS-CE-00672 | 127062-22-0 | Enquire |
Fine Chemicals
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| 5-(Biotinamido)pentylamine | Fine Chemicals | CS-T-49120 | 115416-38-1 | Enquire |
| 6-N-Biotinylaminohexanol | Fine Chemicals | CS-T-49133 | 106451-92-7 | Enquire |
| ATP-polyamine-biotin | Fine Chemicals | CS-ZE-01916 | 1800401-93-7 | Enquire |
| Biotin 5-Bromopentylamide | Fine Chemicals | CS-T-49121 | 1217605-72-5 | Enquire |
| Biotin-4-Fluorescein | Fine Chemicals | CS-T-49125 | 1032732-74-3 | Enquire |
| Diethyl Malonate | Fine Chemicals | CS-T-18198 | 105-53-3 | In Stock |
| DL-Biotin | Fine Chemicals | CS-O-33616 | 22377-59-9 | Enquire |
| N-Biotinyl-1,6-hexanediamine | Fine Chemicals | CS-T-49149 | 65953-56-2 | Enquire |
Building Blocks
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| "N-Biotinyl-N-Boc-1,6-hexanediamine" | Building Blocks | CS-T-49142 | 153162-70-0 | Enquire |
| 2-[Na-Benzoylbenzoicamido-N6-(6-biotinamidocaproyl)-L-lysiny... | Building Blocks | CS-T-48718 | 910036-44-1 | Enquire |
| Ibrutinib-biotin | Building Blocks | CS-ZB-30717 | 1599432-18-4 | Enquire |
| N-Biotinyl-N-(N-Boc-S-trityl)cysteinyl Ethylenediamine | Building Blocks | CS-T-49143 | 508234-94-4 | Enquire |
| N-Fmoc-N\\-Biotinyl-D-lysine | Building Blocks | CS-DV-03655 | 110990-09-5 | Enquire |